Biotin 표지법에 의한 질트리코모나스의 표면 항원 분리

우남식(Nam-Sick Woo),민득영(Duk-Young Min),임미혜(Mi-Hyea Leem),최영길(Yong-Keel Choi) 대한기생충학열대의학회 1993 The Korean Journal of Parasitology Vol.31 No.1

경피적 Scopolamine 부착제제가 경막외 Morphine 사용후 동반되는 구역과 구토에 미치는 효과

우남식(Nam Sick Woo) 대한통증학회 1989 The Korean Journal of Pain Vol.2 No.2

N/A Epidural morphine provides excellent analgesia for the management of postoperative pain, but nausea and vomiting are a commonly reported side effect. Scopolamine, a belladona alkaloid, is an effective antiemetic when nausea is induced by morphine. Transdermal scopolamine patches have the advantage of delivering a constant low dosage of the drug over a prolonged period. To evaluate the efficacy of prophylacitic transdermal scopolamine in reducing nausea or vomiting associated with postoperative epidural morphine analgesia, I studied 60 healthy adult patients. The patients were divided into 3 groups, each group consisting of 20 patients. Group 1; no scopolamine for control Group 2; transdermal scopolamine placebo patch Group 3; transdermal scopolamine patch All patients were anesthetized by epidural injection of 2% lidocaine 15 ml and 0.5% bupivacaine 10 ml with morphine 4 mg. A Comparison with the control group, the placebo group, and Group 3, indicated, that the transder- mal scopolamine reduced the incidence of nausea or vomiting associated with postoperative epidural morphine analgesia (group 1; 35%, group 2; 25%, group 3; 10%). However there were no statisfically significant differences between groups at a level of p>0.05.

체열촬영술을 이용한 성상신경절 차단의 평가

박영주(Young Joo Park),우남식(Nam Sick Woo),이예철 대한통증학회 1994 The Korean Journal of Pain Vol.7 No.2

Thermography is a non-invasive, comfortable, diagnostic technique to monitor successful sympathetic block. We observed abnormal thermal distribution during disease state and then followed with thermography on the process of treatment with stellate ganglion block.

암성 상복부 통증 환자의 내장신경 차단시 관찰한 체열촬영 소견

이상훈(Sang Hun Lee),우남식(Nam Sick Woo),이예철(Y 대한통증학회 1994 The Korean Journal of Pain Vol.7 No.1

N/A Splanchnic nerve block is effective in relief of upper abdominal cancer pain. But we often get confused at the unexpected complaints of pain accompanying a metastatic of referred ori- gin i#n spite of the precise block under image intensifier. We could found aut a thermographic change from the diffuse hyperemission state of abdo- men before the block to the localized state after the block. Itay be helpful in differentiating objectively the accuracy of the block at the unexpected complaints of pain by using thermography before and after the block.

기관내 삽관시 Nitroglycerin Patch 부착과 Fentanyl 투여에 의한 혈압 및 심박동수의 변화

우남식,이진경,이규창,이예철,김혜순 건국대학교 의과학연구소 1991 건국의과학학술지 Vol.1 No.-

The effects of nitroglycerin patch(NG patch) and fentanyl on arterial pressure and heart rate during laryngoscopy and intubation were studied in 40 adult hypertensive patients. Two groups of 20 patients were observed. Patients were randomly assigned to thiopental 5㎎/Kg alone(control group) or NG patch and fentanyl 2 ㎍/Kg with thiopental 5㎎/Kg(study group) for induction of anesthesia. The changes of blood pressure(BP) and heart rate(HR) were measured during the preinduction period, after induction, immediately after intubation and 1, 3 and 5 minutes after intubation. In each group, the values were compared with preinduction period values between two groups. The results were as follows. The control group showed a significant increase of BP and HR, BP was returned to preinduction value within 5 minutes, but HR was not returned to preinduction value within 5 minutes. The study group showed a significant increase of BP and HR, and they returned to preinduction values within one to three minutes. The increase of the magnitude of BP and HR in control group was greater than that of study group and all parameters, except systolic pressure after induction, were significantly different between two groups. It is suggested from the above results that application of NG patch and fentanyl 2㎍/Kg reduces the magnitude and duration of BP and HR elevation following intubation.

상복부수술을 위한 흉부경막외 마취

우남식,최령,조돈행 대한마취과학회 1987 Korean Journal of Anesthesiology Vol.20 No.6

Patients with advanced pulmonary tuberculosis suffer from chronic obstrutive pulmonary disease, making them poor risks for anesthesia. Also, general anesthesia for patients with active hepatitis or arteriosclerotic cardiovascular disease complicates the intraoperative and postoperative course. Inhalation anesthetics, along with the assissted ventilation used in general anesthesia, further complicate the intraoperative and postoperative course. Although regional anesthetic techiques have been used extensively for pelvic and limbic surgery to avoid the complications of general anesthesia, thoracic epidural anesthesia has not been common for upper abdominal surgery because of the fear of damage to the spinal cord. But compared with the lumbar. approach, the danger of accidental damage to the spinal cord has been exaggerated. Thoracic epidural anesthesia has been employed in a number of cases of upper abdominal surgery at Y.U.W.M.C wish remarkable success. We have in describe the use of thoracic epidural anesthesia for upper abdominal surgery.

Atracurium 투여에 의한 기관내삽관의 임상적 평가

우남식,이예철 대한마취과학회 1989 Korean Journal of Anesthesiology Vol.22 No.3

The usefulness of nondepolarizing muscle relaxants for intubation is limited by a relatively slow onset of neuromuscular block compared to that achived with succinylcholine. But, authors have reported that larger doses of nondepolarizing muscle relaxants produce a more rapid onset of maximal neuromuscular block and conditions conductive to endotracheal intubation and recent reports support the use of the $quot;priming principle in the clinical practice of anesthesiology. This phenomenon may apply to all nondepolarizing relaxants: it is reported to facilitated neuromuscular blockade and tracheal intubation when used with atracurium, vecurouium, alcuronium or pancuronium. In this study, administering a small subclinical dose of atracurium (75μg/kg) Smin. prior to the remainder of an intubating doae of atracurium (250μg/kg) had no different on grade of block for intubation compared to single IV bolus of atracurium (500μg/kg).

다발성 늑골골절 환자에서 경막외강내 Narcotics 를 이용한 치료 : 1예 보고

우남식,이예철 대한마취과학회 1988 Korean Journal of Anesthesiology Vol.21 No.6

Pain relief becomes a major concern when treating patients with rib fractures so adequate ventila-tion must be maintained. Many thniques have been described for the management of frectured ribs, including systemic analgesics, intercostal nerve blockade, intrathecal morphine, epidural bupivacaine and epidural morphine. This case report illustrates the successful use of epidural narcotics in a patient with multiple fractured ribs.

마취기의 일방향성 밸브의 결손이 호기 및 흡기의 가스 농도에 미치는 영향

우남식 건국대학교 의과학연구소 1995 건국의과학학술지 Vol.5 No.-

Recent advances in technology have made it possible to measure all of the respired gases of interest during the administration of an inhaled anesthetic. The results of respiratory gas analysis can provide information about the function of the andsthesia delivery system(machine, vaporizer, circuit, valve, etc.) as well as the patient's respiratory, cardiovascular and metabolic status. The semi-closed circle absorber anesthesia system employs individual inhalation and exhalation unidirectional check valves to guide the flow of gas within the circuit and prevent CO₂rebreathing. The most common malfunction in these unidirectional check valves is one in which the valve disc fails to close. The present investigation was designed to study effect of incompetent unidirectional valves on the changes of the partial pressure of inhaled and exhaled CO₂, the fraction of inhaled and exhaled O₂,arterial O₂saturation, blood pressure and heart rate. An DAMECA anaesthesia machine(Denmark) with a semi-closed circle absorber system was used for the study. All patients were anesthetized with the enflurane or isoflurane combined with nitrous oxide(2 liters/minute) and oxygen(2 liters/minute), and paralized with vecuronium(6-8㎎). Ventilation was controlled with DAMECA ventilator, using a constant tidal volume of 10㎖/㎏ of body weight. Ventilatory rate was adjusted 10-12 times/minutes to maintained the end tidal CO₂of 25~30㎜Hg. After a clinical steady state was achived, measurements were obtained till the partial pressure of expiratory CO₂would reach 50㎜Hg, under two condition: 1) removal of inhalation valve disc: 2) removal of exhalation valve disc. The results were as follows: The removal of exhalation valve shows significant increase of ??(regression equation is Y=1.46×X+26.11) and ??(regression equation is Y=1.15×X+4.59). The removal of exhalation valve shows significant decrease of ??(regression equation is Y= -0.31×X+46.66) and ??(regression equation is Y=-0.22×X+49.29), but these were no clinically significant changes. The removal of inhalation valve shows significant increase of ??(regression equation is Y=0.50×X+27.13) and ??(regression equation is Y=0.11×X+1.14). The removal of inhalation valve shows no significant changes in ?? and ??. There were no significant changes in arterial oxygen saturation, systolic and diastolic blood pressure, and heart rate.

악성고열증후군 1예 보고

우남식,이예철 대한마취과학회 1988 Korean Journal of Anesthesiology Vol.21 No.6

The popular term malignant hyperthermia syndrome (MHS) refers to a clinical syndrome classically observed during general anesthesia. It is characterized by a rapidly increasing.temperature and a high mortality rate. A case of MHS was experienced which developed 60 minutes after induction of general anesthesia with thiopental sodium, succinylcholine, halothane, N₂O and O₂. High fever, muscle rigidity and cyanosis developed and were followed by arrythmia and unstable blood pressure. Anesthesia was terminated and vigorous emergency treatment was attempted. The patient died about 6 hours after induction of anesthesia.