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      • KCI등재후보

        Aeromonas 균혈증에 대한 임상적 고찰

        현상(Hyun Sang Won),우석(U Seouk Ahn),이규춘(Ku Chun Lee),이원욱(Weon Uk Lee),김기중(Ki Jung Kim),성낙천(Nak Cheon Seong),김구엽(Koo Yup Kim),서환조(Hwan Jo Suh) 대한내과학회 1997 대한내과학회지 Vol.52 No.3

        N/A Objectives: Aeromonas species is a gram-negative, facultative anaerobe of the family Vibrionaceae. The organism has been recognized as a pathogen associated with illness in human, such as acute gastroenteritis, cellulitis, septicemia, and other rare diseases. Methods: To evaluate the clinical significance of Aeromonas bacteremia in Korea and it's susceptibility of antibiotics, we evaluated the 17patients with Aeromonas bacteremia. Identification was done by use of API 20E system and antibiotic susceptibility was tested with disk diffusion method. Results: Male to female ratio was 11:6, and mean age was 54.1years(8-85years) old. Liver cirrhosis was the most common underlying disease(10cases of 17patients, 58.8%a). Other underlying diseases were as follows: gallstone in 2cases, cholangiocarcinoma in 2cases, and aplastic anemia in 1case, cerebral infarction in 1case. But one had no underlying disease. So Aeromonas bacteremia were occurred in 14immunocompromised patients(82.3%), and in 10patients with hepatobiliary diseases, A. hydrophila was most commonly isolated(13cases, 764%), and the A sobria(4cases, 23.5%) was infrequently isolated. The overall fatality was 47%, and there had no significant difference in fatality between A. hydrophila and A sobria All Aeromonas species had resistance to ampicillin and carbenicillin. Conclusion: Because Aeromonas bacteremia may occur through water-borne route, especially in immunocompromised host. We should pay attention to immunocompromised patients, espacially having hepatobiliary disease.

      • DC Bias 특성을 고려한 플라이백 변압기 손실 최적화에 대한 연구

        안현상(Hyun-Sang Ahn),한병철(Byeongcheol Han) 대한전기학회 2021 대한전기학회 학술대회 논문집 Vol.2021 No.10

        변압기는 플라이백 컨버터의 대부분의 손실을 차지하고 있다. 일반적으로 변압기 철손 계산 시 Steinmetz Equation을 이용하는데, 이 식은 변압기의 DC Bias 특성을 고려하지 않고 있다. 따라서 실제 변압기 설계 시 철손에 의한 손실 오차가 발생하여 최소 손실을 가지는 변압기 설계가 어려 울 수 있다. 그리고 철손 증가 시 변압기의 코어 사양 대비 손실 증가로 발열 상승에 따른 자속 포화 현상도 발생할 수 있다. 본 연구에서는 DC Bias 특성을 고려한 플라이백 컨버터 변압기 설계 방법을 제안하고 이를 통해 최소 손실을 가지는 변압기를 설계한다. 에어컨 실내기용 10W급 플라이백 컨버터를 설계하여 실제 변압기 손실 비교 분석하여 제안된 변압기 설계 방법을 검증하도록 한다.

      • KCI등재후보

        Stenotrophomonas maltophilia 감염의 임상 양상

        이원욱(Won Uk Lee),김병준(Byoung Joon Kim),우석(U . Seouk Ahn),현상(Hyun Sang Won),김기중(Ki Joong Kim),성낙천(Nak Cheon Seong),김구엽(Gu Yeup Kim),서환조(Hwan Jo Suh) 대한내과학회 1997 대한내과학회지 Vol.53 No.3

        N/A Objective: Stenotrophomonas maltophilia has been emerging as an important nosocomial pathogen in recent years in patients with impaired host- defense mechanism or who has been exposed to large amount of inocula. This organism is usually resistant to multiple (commonly used) antimicrobial agents, particularly to those of the beta-lactam class. To evaluate the clinical feature of Stenotrophomonas maltophilia infection and in vitro anti- microbial susceptibility, we performed a retrospective study. Methods: We analyzed the result of in vitro antimicrobial susceptibility test for 200 isolates of S. maltophilia and the annual isolation rate during the period between January 1990 and December 1994 in our institution, and performed a retrospective study for the available records of 165 cases among them. The data were obtained with only the first isolation of the organism for each patients. Results : Total of 165 initial isolates, the isolates were from wounds in 50(30.3%), urine in 47(28.5%), the respiratory tract in 37(22.4%), blood in 9(5.5%), bile in 6(3.6%), and miscellaneous sources in 16(9.7%). The 84.2% of isolates were hospital-acquired isolate and 58.3% of these patients had received antecedent antibiotic therapy: polymicrobial growth was demonstrated in 61.9% of the cases. In vitro antimicrobial susceptibiiity test, ofloxacin was active against the isolates in 89.2%, moxalactam in 85.9%, ciprofloxacin in 83.9%, TMP-SMX(trimethoprim-sulfamethoxazole) in 64.2%, As expected, S. maltophilia isolates were, in general, not susceptible to cephalosporins, penicillins. The annual isolation rate at Kyung Hee University hospital was not increased significantly from 1990 to 1994, 19.53 per 10,000 patients dismissals in 1990, 13.56 in 1994. The major underlying diseases of patients were malignancy(17.6%), cerebrovascular disorder(17%), diabetic mellitus(13.3%). Mortality rate is 10.3%. Conclusion: S. maltophilia has been emerging as an important nosocomial pathogen in immunocompromised patients, especially those receiving broad-spectrum antimicrobial therapy. And this organism is resistant to multiple antimicrobial agents, particularly to those of the beta-lactam class. When antimicrobial treatment is necessary, the clinician should be guided by results of in vitro susceptibility testing because of the notable in vitro resistance of S. maltophilia to commonly used antibiotics. And when S. maltophilia has been recovered from a patient, wound and contact isolation is warranted.

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