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신현우(HY Shin),박정근(JK Park),김태선(TS Kim),송인문(IM Song) 대한산부인과학회 1976 Obstetrics & Gynecology Science Vol.19 No.7
A case of large pedunculated submucous myoma of the uterus has been reported with a brief review of literature on uterine myoma was made. This tumor was approximately child head sized.
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박정근(JK Park),신현우(HY Shin),박호형(HH Park),김태선(TS Kim) 대한산부인과학회 1975 Obstetrics & Gynecology Science Vol.18 No.10
1. The mean age was 31.9 and 27.1% of total were between 31 and 35 year of age. 2. frequency of ecoptic pregnancy showed decreasing tendency in inverse proportion to the NO. of parity and induced aboriton. 3. 44.5% had history of artificial abortion. It was suspected to be an important factor in developing ectopic pregnancy. 4. Lower abdominal pain was in 93.9% amenorrea in 64.0% vaginal bleeding in 77.3% nausea nad vomiting in 66.0% hypovolemic shock in 27.1% danforth sign in 23.0% and palpable adnexal mass in 45.3%. 5. As far as the time of onset of symtoms is concerned , they were developed initially within 6 weeks after L.M.P in 58.8% and within 8 weeks in 79.0%. 6. Culdocentesis was accuarate in 91.1% of total negative in 4.9% and failed in 4.0%. 7. Of tubal pregnancies the right side of the tube was involved in 53.2% left tube in 46.8% among whivh 80.8% were in the ampulla 12.2% in the isthmus, 3.7% in the interstital portion.
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박인사(IS Park),탁혜정(HJ Tack),신현우(HY Shin),박호영(HY Park) 대한산부인과학회 1974 Obstetrics & Gynecology Science Vol.17 No.10
좌측난소갑상선종 1예를 보고하고 그 문헌적 고찰을 하였다. A case of struma ovarii was reported with brief review of literatures. The tissue fragments of tumor were composed of thyroid tissue exclusively and no other dermoid element could be seen. Pre-and post-op I uptake were within normal limit.
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체외수정 배양액에 대한 제대혈청 및 단백질 첨가의 난자성숙 및 난구 세포 분산에 미치는 영향
신현우,이여일,박현정 대한산부인과학회 1995 Obstetrics & Gynecology Science Vol.38 No.7
본병원 체외수정 시술후 임신된 배양액군과 임신에 실패한 배양액군에서 각각 Ham`s F-10 기본 배양액 및 소혈청단백 또는 태아제대혈청 첨가 배양액하에서 생쥐의 난자-난구 복합체 를 22시간 동안 배양하고 난자의 성숙도와 난구세포 분산정도를 비교분석한 결과 다음과 같은 성적을 얻었다. 1. 난자성숙의 진행정도는 Ham`s F-10 기본배양액과 소혈청단백 및 태아제대혈청첨가 배양 액 사이에 유의한 차이가 없어 두가지 첨가물 모두 난자 성숙에는 별로 영향을 주지않는 것으로 보인다. 2. 난구세포 분산에 있어서는 태아제대혈청 첨가배양액 만이 저명한 발현을 보여 이 혈청내 난구세포 분산 자극물질의 존재를 시사하였다. 3. 난자성숙과 난구세포 분산 공히 기본 배양액과 첨가 배양액에서 임신군과 비임신군 간에 유의한 차이가 없어 체외수정 성공여부와는 무관한 결과를 나타냈었으나, 생쥐 난자-난구 복합체 배양은 종전의 배아 배양 정도관리시 파악할 수 없었던 수정전 및 수정시기의 배양 조건의 질적평가에 새로운 시야를 제공하였다. OBJECTIVE : To investigate of effect of human cord serum(HCS) and bovine serum albumin(BSA) supplementation on oocyte maturation and cumulus cell expansion in vitro culture media. DESIGN : Random sampling of 6 conceptional media from 7 patients and 8 nonconceptional media from 14 patients resulted from our in vitro fertilization and embryo transfer(IVF-ET) program. Each medium was divided to three groups : Ham`s F-10(unsupplemented), Ham`s F-10 supplemented with 0.4% BSA and Ham`s F-10 supplemented with 10% HCS. Setting, Patients : In vitro fertilization (IVF) program and patients at the IVF clinic of Chonman University Hospital Kwangju. Korea. Interventions : oocyte cumulus cell(OCC) complexes were collected from removed ovaries of pregnant mare serum gonadotropin(PMSG) primed mice, and cultured in three different media. Main outcome Measures : The oocyte maturities were measured by the presence of germinal vesicle breakdown and polar body, and the cumulus cell expansions were analyzed by the degree of cellular dispersion. Results : Oocyte maturity was not significantly different among the three types of media. cumulus cell expansion was significantly increased only by HCS-supplemented media. Comparison of oocyte maturity and cumulus cell expansion among groups showed no significant differences between conceptional and nonconceptional media. Conclusions : The supplementions with HCS or BSA are not able to augment mouse oocyte maturation. The great cumulus expansion in HCS supplemented media suggest the presence of stimulatory in OCC complex. The OCC complex culture provides new insight into qualitative information on prefertilization and perifertilization events.
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