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증례 : 하시모토 갑상선염에서 갑상선 유두암과 여포암이 동시 발견된 1예
홍진헌 ( Jin Hon Hong ),남수민 ( Soo Min Nam ),이미영 ( Mi Young Lee ),고장현 ( Jang Hyun Koh ),신장열 ( Jang Yeol Shin ),정춘희 ( Choon Hee Chung ),조미연 ( Mee Yon Cho ) 대한내과학회 2007 대한내과학회지 Vol.72 No.5
저자들은 하시모토 갑상선염 환자에서 갑상선 유두암과 여포암이 동반되어 발생한 드문 예를 경험하여 보고하는 바이며 하시모토 갑상선염 환자에서 갑상선 결절에 대한 적절한 추적과 감시가 갑상선 암의 조기 발견과 치료에 도움이 될 수 있을 것으로 생각한다. We report here on a rare case of papillary and follicular carcinoma of the thyroid gland that developed in a 31 years old woman who was previously diagnosed with Hashimoto`s thyroiditis. Her chief complaint was a palpable neck mass. The antimicrosomal and antithyroglobulin antibody levels were elevated. Ultrasonography of the left thyroid gland revealed a 2.5×2.0 cm sized thyroid nodule. Fine needle aspiration biopsy of the thyroid nodule was done and this was diagnosed as Hashimoto`s thyroiditis. There was no evidence of thyroid cancer. After 1 year, thyroid ultrasonography and biopsy were repeated for examining an enlarged thyroid nodule. Total thyroidectomy was then performed. The histopathologic examination revealed that the right and left thyroid glands were in accordance with the diagnosis of papillary and follicular cancer, respectively. Until now, no known case of simultaneous papillary and follicular carcinoma in Hashimoto`s thyroiditis has been reported. This case suggests that adequate follow up for Hashimoto`s thyroiditis patients with thyroid nodule may help the early detection and management of thyroid cancer. (Korean J Med 72:558-562, 2007)