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면역글로불린 M 의 증가가 동반된 면역글로불린 결핍증 1 예
임종섭(Jong Seob Lim),류수현(Su Heon Ryu),유대성(Dae Seong Yu),류인열(In Yeol Ryu),윤성준(Seng Joon Yun),이지현(Ji Hyun Lee),신원혁(Won Hyeog Sin),황순철(Soon Chul Hwang) 대한내과학회 1997 대한내과학회지 Vol.52 No.1
N/A Immunoglobulin deficiency with increased IgM, as defined by World Health Organization classification of primary immunodeficiency, is characterized by normal or increased concentrations of serum IgM and, in some cases, IgD, but decreased or absent IgG, IgA, and IgE. Patients with these disorders have a high incidence of recurrent pyogenic infections, including otitis media, pneumonia, and septisemia. We recently experienced a case of immunoglobulin deficiency with increased IgM in a 25-year old man. He had been suffered from recurrent pyogenic infections-pneumonia, otitis media-since about 6 months of his age. He was admitted due to pneumonia, and Haemophilus influenza was isolated from the sputum culture. Also chest X-ray showed bronchiectasis. His serum immunoglobulin levels revealed increased concentration of IgM and decreased IgG and IgA. He was successfully treated with antibiotics, and now he is being followed-up. So we present this case with the review of literature.