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전이성 대장암 환자에서 동시성 및 이시성 간전이 종양의 Cyclooxygenase (COX)-1과 Cyclooxygenase (COX)-2 및 E-cadherin 발현의 의의
주선형(Sun Hyung Joo),김범수(Bum Soo Kim),최성일(Sung Il Choi),송정윤(Jeong Yoon Song),이길연(Kil Yeon Lee),김윤화(Yun Wha Kim),김교영(Gyo Young Kim),이석환(Suk Hwan Lee),이상목(Sang Mok Lee),홍성화(Sung Wha Hong) 대한외과학회 2010 Annals of Surgical Treatment and Research(ASRT) Vol.78 No.3
Purpose: Recent studies have shown that cyclooxygenase (COX)-2 may be involved in colorectal carcinogenesis. In this study, we evaluate the differences of COX-2 expression in patients with synchronous and metachronous hepatic metastasis of colorectal cancer. In addition, the expression of COX-1 and E-cadherin were also evaluated. Methods: Paraffin embedded blocks were obtained from 41 patients who underwent surgery for colorectal cancer with hepatic metastasis. Samples from primary colorectal cancer, synchronous and metachronous hepatic lesions were stained by immunohistochemistry for monoclonal antibody against COX-1, COX-2, and E-cadherin. Results: In colonic COX-1 expression, there was no significant difference in the degree of COX-1 expression between primary colorectal cancer with synchronous hepatic metastasis and that of metachronous hepatic metastasis (P=0.507). In colonic COX-2 and E-cadherin expression, the degree of COX-2 expression was not different between the two groups. But, the patient survival rate in the positive group of COX-1 and COX-2 expression was lower than in the negative group, respectively (P=0.023, P=0.006). Conclusion: The degree of colonic COX-1 and COX-2 expression has an impact on prognosis in synchronous and metachronous hepatic metastasis. Further large-scale study is necessary to determine the meaning of COX-2 expression in colorectal cancer.
티타늄이 증착된 유리를 사용한 FTO-less 염료감응형 태양전지에 관한 연구
박송이(Songyi Park),서현웅(Hyunwoong Seo),손민규(Min-Kyu Son),김수경(Soo-Kyoung Kim),홍나영(Na-Yeong Hong),송정윤(Jeong-Yun Song),프라바카르(Kandasamy Prabakar),김희제(Hee-Je Kim) 대한전기학회 2013 전기학회논문지 Vol.62 No.2
Dye-sensitized solar cells (DSCs) have taken much attention due to their low cost and easy fabrication method compare to silicon solar cells. But research on cost effective DSC is prerequisite for commercialization. Fluorine doped tin oxide (FTO) which have been commonly used for electrode substrate as electron collector occupied most percentage of manufacturing cost. Therefore we studied FTO-less DSC using sputtered Ti deposited glass as photoelectrode instead of FTO to reduce manufacturing cost. Ti films sputtered on the glass for different time, 5 to 20 minutes with decreasing sheet resistance as deposition time increases. A light source illuminated to counter electrode in order to overcome opaque Ti films. The efficiency of DSC (Ti20) made Ti sputtered glass for 20 min as photoelectrode was 5.87%. There are no significant difference with conventional cell despite lower manufacturing cost.