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간질환에서의 (肝疾患) Free Cholesterol 과 지방산 (脂肪酸) 종류에 따른 각종 Cholesterol Ester 함량
허정욱(Jung Wook Hur),김정철(Jung Chul Kim),전영준(Young Joon Jeon),박승국(Seong Kook Park),서준수(Joon Soo Suh),정태호(Tae Ho Chung) 대한소화기학회 1985 대한소화기학회지 Vol.17 No.1
N/A Abnormalities of cholesterol metabolism has been often suspected in patients with liver diseases. Hence we determined the free and esterified cholesterol in patients with liver diseases including acute and chronic hepatitis, hepatic cirrhosis, hepatoma, and obstructive jaundice comparing with healthy subjects. The method in this study has tried to extract the free and esterified cholesterol by organic solvent, n-Octane, the total cholesterol was extracted by hexane after hydrolysis of the esterified cholesterol by ethanolic KOH. Free, esterified and total cholesterol were measured by high pressure liquid chromatography. Patients with liver diseases have higher level of unesterified cholesterol than healthy subjects. Cholesteryl linoleate per cholesteryl oleate ratio in hepatic cirrhosis and acute hepatitis patients were significantly lower than those of healthy subjects. Levels of cholesteryl arachidonate in hepatic cirrhosis and obstructive jaundice patients were significantly lower than healthy subjects.
各種 癌患者에 對한 X-線照射時 Tubercin-3 投與가 血淸蛋白의 電氣泳動像에 미치는 效果(第1報) : 特히 子宮頸部癌 25例에 對한 觀察
徐俊洙,崔漢鏞,羅雨淵,鄭泰浩 慶北大學校 醫科大學 1976 慶北醫大誌 Vol.17 No.1
1975年 6月부터 1976年 5月까지 約 1年間에 本大學附屬病院 放射線學敎室에서 放射線療法을 實施한 25例의 子宮頸部患者을 X-線만으로 治療한 14例와 X-線照射治療와 Tubercin-3治療 兩者를 同時에 實施한 11例의 두 群으로 나누어 治療前後의 血淸의 電氣泳動像을 검토하여 본 結果 放射線療法을 實施한 25例의 期間中 血球 및 血小板의 檢査는 正常範圍에 있었고 血淸蛋白量은 異常値를 보이지 않았다. 放射線療法만을 實施한 14例中 좋은 豫後를 取한 10例의 血淸蛋白電氣泳動像과 放射線療法과 Tubercin-3療法을 同時에 實施한 11例의 血淸蛋白 電氣泳動像은 正常人의 泳動像과 別差異을 보이지 않았다. 放射線療法만을 實施하였으나 不良한 豫後를 取하여 放射線 治療後 早期에 死亡한 4例의 電氣泳動像은 正常과는 달리 α-glubulin 分劃과 γ-globulin 分劃에 異常을 認知할 수 있었다. From June, 1975, to May, 1976,the electrophoretic patterns of serum protein among the 25 cases of cervical cancer during the treatment with X-irradiation have been studied. To observe the effect of Tubercin-3 on patterns of serum electrophoresis the patients were divided into 2 groups; X-irradiation and X-irradiation with Tubercin-3 treatment. The hematological analysis were also carried out before and after X-irradiation. The serum total protein and routine hematological analysis of all these 25 case showed within normal limit during experimental period of the time. The serum electrophoretic patterns of 10 cases of good prognosis and Tubercin-3 treated 11 cases were un-remarkable. Abnormal raises of α-and γ-globulin fractions were observed in the 4 cases of poor prognosis.