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RISS 인기검색어
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- 저자 : 서일국 ( Il Kook Seo ) (검색결과 2 건)
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서일국 ( Il Kook Seo,),최인선 ( In Seon S. Choi ),김상훈 ( Sang Hoon Kim ),한의령 ( Eui Ryoung Han ) 대한천식알레르기학회 2011 천식 및 알레르기 Vol.31 No.1
Background: Anti-asthma treatments correct impaired dyspneaperception. Objective: To investigate whether dyspnea perception in asthmatics vary whenever they are hospitalized. Method: We retrospectively analyzed the medical records of 64 patients (32 men and 32 women) with acute asthma who were hospitalized at least twice and assessed using the Borg scale-based dyspnea perception score while breathing through an inspiratory muscle trainer at each admission. Poor perceiver was defined as a Borg score of ≤5 at the highest resistive load (HR) and HR-induced ΔBorg score of ≤3. Result: Between the first and econd admissions, the relationship of forced expiratory volume in 1 s (r=0.773, P <0.001) and the concordance of severity of asthma attack (κ=0.503, P<0.001) were significant, but the relationship of HR-induced ΔBorg score and the concordance of poor perceivers were not. During the first admission, as lung function increased gradually, the HR-induced ΔBorg score became higher in poor perceivers (1.83±0.39→3.42±0.57→4.00±0.67, P=0.048). Conclusion: Although asthmatic patients who suffered from a severe asthma attack tended to have a severe attack again at the following admission, dyspnea perception differs among the admissions. Impaired dyspnea perception during acute asthmatic attack would be correctable with anti-asthma treatments. (Korean J Asthma Allergy Clin Immunol 2011;31:20-26)
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말기 암 환자의 생존기간 예측: 혈액학 검사와 PPI에 대한 전향적 연구
손효림 ( Hyo Rim Son ),김대은 ( Dae Eun Kim ),강현욱 ( Hyun Wook Kang ),김하나 ( Ha Na Kim ),서일국 ( Il Kook Seo ),윤주영 ( Ju Young Yoon ),황준일 ( Jun Eul Hwang ),심현정 ( Hyun Jeong Shim ),조상희 ( Sang Hee Cho ),정익주 ( Ik J 대한내과학회 2011 대한내과학회지 Vol.81 No.3
Background/Aims: The palliative prognostic index (PPI) was designed to predict life expectancy based on clinical symptoms. In this study, a PPI was constructed and used with other biological parameters to predict 3-week survival in patients with advanced cancer. Methods: The study included 222 patients. The PPI was constructed with five variables (performance status, oral intake, edema, dyspnea at rest, and delirium). PPI scores were grouped as follows: 4 (group 1); > 4 and ≤ 6 (group 2); and > 6 (group 3). At admission, seven biological variables (white blood cell count, lymphocyte, C-reactive protein [CRP], bilirubin, albumin, creatinine, and lactate dehydrogenase) were measured. Results: The overall survival duration was 50 days in group 1, 22 days in group 2, and 14 days in groups 3. Using the PPI, a survival of < 3 weeks in group 3 was predicted with a sensitivity of 76.5% and a specificity of 65.4%. The important factors significantly affecting the 3-week survival rate were a PPI score > 6 and increases in serum bilirubin and CRP levels. Furthermore, the 3-week survival rate in patients with hepatopancreatobiliary cancer was more accurately predicted using a combination of the PPI, CRP, and serum bilirubin levels. Conclusions: Although a PPI has limitations, it can be quickly applied to determine survival duration in patients admitted to hospice and accurately predicts 3-week survival. Furthermore, bilirubin and CRP are useful factors for predicting 3-week survival in patients with gastrointestinal cancer, including hepatopancreatobiliary cancer. (Korean J Med 2011;81:359-365)
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