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만성 C형 간염 환자에서 발생한 Pegylated 인터페론 알파2a에 의한 지방층염
백유상 ( Yoo Sang Baek ),김종엽 ( Jong Yeob Kim ),최재은 ( Jae Eun Choi ),안효현 ( Hyo Hyun Ahn ),계영철 ( Young Chul Kye ),서수홍 ( Soo Hong Seo ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.7
Interferon (IFN) α is commonly used for the treatment of chronic hepatits C with a combination of ribavirin. There are numerous dermatologic adverse events of IFN, such as xerosis, pruritus, alopecia, and injection site reaction. Panniculitis is one of the rare cutaneous side effects of IFN treatment, which may have a significant reduction on patient`s quality of life and may lead to discontinuation of the treatment. Although there have been several reports of panniculitis induced by IFN-β, IFN-α induced panniculitis are rarely reported in the literature. Herein, we report a case of panniculitis caused by pegylated IFN α2a injection in a patient with chronic hepatitis C. (Korean J Dermatol 2012;50(7):640∼643)
백유상 ( Yoo Sang Baek ),신원웅 ( Won Ung Shin ),오태석 ( Tae Seok Oh ),손수빈 ( Soo-Bin Son ),송해준 ( Hae Jun Song ),오칠환 ( Chil Hwan Oh ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.1
Vitamin K1 dermatitis is a cutaneous adverse reaction to vitamin K1, and this malady presents as an erythematous eczematoid patch or pseudoscleroderma. At first, liver disease was thought to be related to vitamin K1 dermatitis. However, it is no longer considered as being related to liver disease due to the increasing case reports of patients with vitamin K1 dermatitis and who are without liver disease. Type IV hypersensitivity reaction was suspected to be the cause of this reaction. This disease can be easily ignored because of its low incidence. We hereby report on a case of vitamin K1 dermatitis that was confirmed by a skin test. (Korean J Dermatol 2011;49(1):58~61)
백유상 ( Yoo Sang Baek ),신원웅 ( Won Ung Shin ),오태석 ( Tae Seok Oh ),손수빈 ( Soo Bin Son ),송해준 ( Hae Jun Song ),오칠환 ( Chil Hwan Oh ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.7
Kaposi`s sarcoma (KS) is a multifocal proliferative vascular tumor involving cutaneous and extra-cutaneous tissues. KS has been reported in patients treated with immunosuppressive agents for autoimmune diseases. However, KS has rarely been reported in patients with iatrogenic Cushing`s syndrome. A 77-year-old woman was evaluated with multiple asymptomatic violaceous nodules and plaques on both lower legs. She had been diagnosed with iatrogenic Cushing`s syndrome and had been treated with low-dose corticosteroid replacement therapy for >10 years. A histopathologic study showed extensive vascular proliferation in the dermis with spindle-shaped cells. Immunohistochemical staining for CD31, CD34, human herpesvirus (HHV)-8, and D2-40 was positive. We hereby report a case of KS in a patient with iatrogenic Cushing`s syndrome.
백유상 ( Yoo Sang Baek ),이정우 ( Jung Woo Lee ),안재우 ( Jae Woo Ahn ),김주하 ( Joo Ha Kim ),전지현 ( Jiehyun Jeon ),송해준 ( Hae Jun Song ),오칠환 ( Chil Hwan Oh ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.5
Squamous cell carcinoma (SCC) of the maxillary sinus is the most common malignant neoplasm of the paranasal cavity. The most frequent initial symptoms are swelling of the cheek, nasal obstruction, epistaxis, and nasal discharge. Herein, we report the case of a 62-year-old Korean male who initially presented with a whitish irregular depressed plaque with an indurated border in his left cheek. After a several-week delay in diagnosis, he was eventually diagnosed with maxillary sinus carcinoma. (Korean J Dermatol 2014;52(5):349∼352)
발바닥에 발생한 항Ro 및 항La 항체 양성과 연관된 윤상 홍반
백유상 ( Yoo Sang Baek ),김주하 ( Joo Ha Kim ),신원웅 ( Won Ung Shin ),김재환 ( Jae Hwan Kim ),송해준 ( Hae Jun Song ),오칠환 ( Chil Hwan Oh ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.4
Recurrent annular erythema associated with anti-Ro/La antibody is a diagnostic term for annular erythemas that usually occurs in the face and the upper extremities of patients with positive anti-Ro/La antibodies. They have been reported in patients with Sjogren`s syndrome, lupus erythematosus, or Sjogren`s syndrome/systemic lupus erythematosus syndrome. Recently, there have been cases without any underlying autoimmune diseases. We, hereby, report an annular erythema, associated with anti-Ro/La antibody occurring in both soles, which is an unusual location for this disease. (Korean J Dermatol 2012;50(4):350∼353)