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RISS 인기검색어
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- 저자 : 백승철 ( Seung Churl Baek ) (검색결과 3 건)
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스트레스 관련 피부질환 환자의 혈장내 β - endorphin의 변화
백승철 ( Seung Churl Baek ),김정원 ( Chung Won Kim ) 대한피부과학회 1995 대한피부과학회지 Vol.33 No.5
Background : Stress has long been known to play a role in many dermatologic disorders ard can affect the onset and course of the disorder in some patients. Stress-induced exacerbation or onset of symptoms has been reported in chronic urticaria, alopecia areata, berpes simplex, herps zoster, and psoriasis vulgris, and these diseases can be classified as stress-associated dermatoses. Beta p-endorphin is one if the most important mediators of stress, which is known to be generat ed upon stimulation of t.he pituitary adrenal axis, and its secretion increases during periods of stress. Objective : In order t,o see wheather p-endorphin might be related to the onset or recurrence of stress-associated dermatses, we compared the plasma concentration of p-endorphin in patients with stress associated dematoses with those of healthy subjects. Methods : The concentation of p-endorphin in sera was quantified by radioimmunoassay, usirg the INCSTAR 'IRIA Kit for plasma p-endorphin. Each patient was asked to indicate if they be lieved that their skin proilem began after an important stressful event in their lives. Results : There was no significant difference in plasma p-endorphin levels between patient,s with chronic urticaria, alopeciareata, herpes simplex, and herpes zoster and healthy subjects(p>0.05), whereas in patients witi psoriasis vulgaris, plasma level of p-endorphin was significantly in creased(p<0.001). There was no relationship between the stressful events and plasma pendorphin concentrations. Conclusions : The plasma p-endorphin level is not correlated with the onset or recurrence of stress-associated dermatuses such as chronic urticaria, alopecia areata, herpes simplex, and herp.s zoster. The increase in p-endorphin in psoriasis vulgaris is more likely that this peptide is generted by the lymphocyte irliltrate in the skin and/or by lymphocytes when they recirculate rath:.r than by the activation of the pituitary-adrenal axis by stress. (Kor J Dermatol 1995;33(5): 841-846)
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최태진 ( Tae Jin Choi ),백승철 ( Seung Churl Baek ),김정원 ( Chung Won Kim ),한지환 ( Ji Hwan Han ) 대한피부과학회 1996 대한피부과학회지 Vol.34 No.1
Congenital onychodysplasia of the index fingers(COIF) is a rare condition of the nails, characterized by the following : (1) congenital occurrence, (2) unilateral or bilateral index finger involvement, (3) variability in nail appearance such as anonychia, micronychia, and polyonychia, (4) possible hereditary involvement, and (5) frequently associated bone anomalies. A 7-week-old male baby with an atrial septal defect presented with micronychia of the left index finger. Roentgenogram of both hands revealed a bone defect of the left 2nd distal phalanx. To our knowledge, distal phalangeal bone defect has not been previously described in this disease. We report a case of COIF with atrial septal defect. (Kor J Dermatol 1996;34(l): 132-135)
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김태윤 ( Tae Yoon Kim ),권윤희 ( Yoon Hee Kwon ),이동원 ( Dong Won Lee ),백승철 ( Seung Churl Baek ),조백기 ( Baik Kee Cho ) 대한피부과학회 1996 대한피부과학회지 Vol.34 No.6
Acrodermatitis enteropathica is a rare autosomal recessive disorder characterized by alopecia, a ral and periorificial derma.titis and gastro-intestinal disturbances such as diarrhea. This syndrome is caused by malab, orption of zinc. The mean serum zinc level is usually low in untreated patients and the oral administration of zinc sulfate can clear the skin lesions and other symptoms. We report a three-month-ol:~3 female baby with acrodermatitis enteropathica showing a normal serum zinc level in whom diapnosis was confirmed by typical skin lesions, clinical symptoms and response to oral zinc therapy. (Kor J Dermatol 1996;34(5): 984 987)
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