肝損傷, 自家移植 및 同種移植이 肝核酸量 및 Transaminase Activity에 미치는 影響

朴浩根 中央醫學社 1964 中央醫學 Vol.6 No.1

One hundred and ten rabbits were divided into 5 groups as follows : Group 1 : Control (Sham operated) Group 2 : Resected at 1/3 portion of left lobe of the liver. Group 3 : Resected at 1/3 portion of left lobe of the liver and autotranplanted in right inguinal region. Group 4 : Ligated at 1/3 portion of left lobe of the liver. Group 5 : Sham operated and homotransplanted in right inguinal region. Fourteen out of 22 rabbits of each group were killed at 24 hours after operation, 8 out of them of each group were killed at 48 hours after operation. Immediately after operation, all animals were given 301gc of Pat intraperitoneally. After killing the animals, middle lobe of the liver were taken out to determine nucleic acid content, P32 incorporation rate into liver nucleic acid and transaminase activity. The results of this experiment were as follows; (1) A. RNA-P content of the liver at 24 hours after operation was 35.3 mg-p/100 gm tissue in the 1st group, 45.2(125.2%) in the 2nd group, 43.6 in the 3rd group, 40.9 in the 4th group and 32.4 in the 5th group. The quantitative order was 2nd group> 3rd group> 4th ,:Youp>1st group> 5th group. B. RNA-P content of the liver at 48 hours after operation was 34. lmg--p/100 gm tissue in the 1st group,41.8(122.2%) in the 2nd group,40.5 in the 3rd group,41.1 in the 4th group and 28.1 in the 5th group. The quantitative order was 2nd gr.> 4th gr.> 3rd gr. 1st gr.> 5th gr. (1l) A. DNA-P content of the 'liver at 24 hours after operation:was z19;1:fng-P/100 gmm tissue in the 1st group, :30.5(159.7%) in the 2nd group, 28.5 in the 3rd group,26.7 in the 4th group and 16.5 in the 5th group The `quantitative order was 2nd ,gr.> 3rd gr.> 4th gr.) 1st gr.> 5th gr. B. DNA-.P content of the liver at 48 hours after operation was 20.5 mg P/100 gm tissue In the 1st group, 28.2(137.6%) in the 2nd group, 28.5 in the 3rd group, 26.8 in the 4th group .and 18.3 in the 5th group. The quantitative order was 3rd -gr.) 2nd gr. )-4th gr.> 1st gr.> 5th gr.. (1f) A. GPT activity of the liver at 24 hours after operation was?36.900 units/gm tissue in the 1st group, 44.550(120.7%) in the 2nd group, 43.080 in the 3rd group, 43.900 in the 4th group and 37.800 in the 5th group. The quantitative order was 2nd gr. )4th gr. ) 3rd gr.) 5th gr.) 1st gr. B. GPT activity of the liver at 48 hours after operation was 45.370 units/gm tissue in the 1st group, 62.850 in the 2nd group, 59.000 in the 3rd group, 84.450(186.4%) in the 4th group and 48.600 in the 5th group. The quantitative order was 4th gr. 2nd gr.) 3rdgr.) 5th gr.> 1st gr. (If) A. GOT activity of the liver at 24 hours after operation was 102.350 units/gm tissue in the 1st group, 129,990 in the 2nd group, 153,450(149.9%) in the 3rd group, 107.200 in the 4th group and 106.500 in the 5th group. The quantitative order was 3rd gr.> 2nd gr. ) 4th gr.) 5th gr.> 1st gr. B. GOT activity of the liver at 48 hours after operation was 128.000 units/gm tissue in the 1st group, 151.350 in the 2nd group, 139.500 in the 3rd group, 186.900(146%) in the 4th group and 136.900 in the 5th group. The quantitative order was 4th gr.> 2nd gr.> 3rd gr.> 5th gr. )1st gr. (V) A. The specific activity of P32 incorporation rate into RNA fraction of the liver at 24 hours alter operation was 3154.8 epm/mg-.P in the 1st group, 5677.4(180%) in the 2nd group, 5526.6 in the 3rd group, 5674.3 in the 4th group and 2972.8 in the 5th group. The quantitative order was 2nd gr.>4th gr.) 3rd gr.> 1st gr.> 5th gr. B. The specific activity of P32 incorporation rate into RNA fracticn of the liver at 48hours after operation was 2187.0 cpm/mg-P in the 1st group, 4609.2(210.8%) in the 2nd group, 3919.4 in the 3rd group, 3122.7 in the 4th group and 2710.3 in the 5th group. The quantitative order was 2nd gr.) 3rd gr.) 4th gr.> 5th gr.) 1st gr. (II) A. The specific activity of P32 incorporation rate into DNA fraction of the liver . at 24 hours after operation was 1570.7 cpm/mg-P in the 1st group, 2645.9(168.5%) in the 2nd group, 2549.6 in the 3rd group, 2065.5 in the 4th group and 1512.1 in the 5th group. The quantitative order was 2nd gr.) 3rd gr.> 4th gr.) 1st gr.> 5th gr. 13. The specific activity of P32 incorporation rate into DNA fraction of the liver at 48 hours after operation was 1458.5 cpm/mg-P in the 1st group, 2806.7(192.4%) in the 2nd group, 2247.4 in the 3rd group, 2065.3 in the 4th group. and 1278.6 in the 5th group. The quantitative order was 2nd gr.> 3rd gr.> 4th gr.> 1st gr.> 5th gr. From the results thus obtained, it may be concluded that the liver injury causes prompt increase of liver nucleic acid content and tranaminase activity, and that transplanted liver tissue inhibits this regenerative reaction. It may be also suggested that increased activity of serum transaminase of liver injured animals resulted from compensatory increase in enzyme production by healthy liver tissue and the source of increased enzyme is healthy, not necrotic, tissue.

‘한국교육정치학회의 발전 과정’에 대한 토론 2

박호근 한국교육정치학회 2004 한국교육정치학회 학술대회논문집 Vol.2004 No.1

지방의회 내 정당 간 관계의 정치학

박호근 한국교육정치학회 2016 한국교육정치학회 학술대회논문집 Vol.40 No.-

이번 한국교육정치학회 2016년 춘계학술대회의 대주제명이 「지방교육행정의 정치 학」이다. 이 중에서 필자가 주제발표를 맡은 부분은 `지방의회 내 정당 간 관계의 정 치학”이다. 이 주제를 본인에게 맡긴 이유는 필자가 현재 서울특별시의원으로서 활동하 기 때문에 그동안의 경험을 바탕으로 그 실태를 발표를 하라는 취지로 이해하고 있다. 이에 지난 2년 여 동안 필자가 보고 느낀 바를 보다 객관적인 입장에서 기술하 고자 한다. 본 발표문의 연구 범위는 서울특별시의회를 중심으로 한다.

국방·군사시설사업 산업재해 발생요인에 대한 발주자 관점에서의 프로젝트 참여자 인식도 차이 파악

박호근,주문부,장재호,김주형,이경태 대한건축학회 2023 대한건축학회논문집 Vol.39 No.11

The enactment of the Serious Accident Punishment Act has increased the importance of safety management for clients. Nevertheless, indefense and military facility projects, the existing safety management system has not experienced significant changes due to challenges relatedto access control, hazardous conditions, and limited expertise. Consequently, this situation has resulted in industrial accidents stemming fromdiffering safety management perspectives among stakeholders. Moreover, safety management primarily concentrates on accidents during theconstruction phase, overlooking clients' dual roles as supervisors. This study aims to improve safety management led by clients by analyzingperspectives from clients, contractors, and supervisors regarding factors contributing to client-induced industrial accidents. A comprehensiverisk management framework was developed reviewing literature and conducting Focus Group Interviews. Data on stakeholders' perceptions ofimportance and performance were gathered through questionnaires and significant perception differences were identified using statisticalanalysis. Importance-performance Analysis further assessed the significance of various factors. These findings revealed disparities in theimportance of four factors and the performance of twelve out of twenty factors. Addressing these differences necessitates appropriate levels ofsupervision and additional training or personnel for on-site oversight. Perception-based variations should be resolved throughconsensus-building processes led by the owner. This research offers valuable insights and a structured framework for optimizing safetymanagement in owner-led scenarios, particularly in high-risk defense and military facility projects.

5·16 군사정부의 교육정책과 결정유형

박호근 한국교육정치학회 2005 敎育政治學硏究 Vol.12 No.2

출하일령 10일 단축방안

박호근,Park, Ho-Geun 대한양돈협회 1991 養豚 Vol.13 No.6

밤나무 주요품종의 실용적 형질 및 수양성에 관한 연구

박호근 忠北大學 1976 論文集 - 忠北大學校 Vol.10 No.S

-본문참고-

파이프 돈사가 성성숙을 촉진시킨다

박호근,Park, Ho-Geun 대한양돈협회 1988 養豚 Vol.10 No.11

사학에서 교원 임면권의 주체, 과연 누가 되어야 하는가

박호근 대한사립학교장회(구 대한사립중고등학교장회) 2004 私學 Vol.109 No.-

교육자치 구현을 위한 사학의 위상과 역할

박호근 대한사립학교장회(구 대한사립중고등학교장회) 2003 私學 Vol.105 No.-