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      저자 : 박혜영 ( Seung-ick Cha ) (검색결과 1 건)
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      • Clinical impact of chronic respiratory disease on clinical features and prognosis of Korean patients with pulmonary thromboembolism

        박혜영 ( Seung-ick Cha ),( Seung-soo Yoo ),( Shin-yup Lee ),( Jaehee Lee ),( Chang-ho Kim ),( Jae-yong Park ) 대한결핵 및 호흡기학회 2018 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.126 No.-

        Background: Data regarding clinical and radiological features of patients with pulmonary thromboembolism (PTE) and concomitant chronic respiratory disease (CRD) are limited. The aim of the present study was to investigate the clinical relevance of CRD in PTE patients. Methods: Retrospectively, PTE patients were classified into PTE patients with CRD and without CRD, and clinical characteristics, blood biomarkers, and computed tomography (CT) findings were compared between the two groups. Results: Overall 1207 PTE patients were included, and CRD was detected in 128 PTE patients (11%). The most common CRD was chronic obstructive pulmonary disease (41 [32%]), followed by bronchial anthracofibrosis (32 [25%]). In multivariate analysis, unprovoked PTE, Pulmonary Embolism Severity Index (PESI) class IV-V, pulmonary artery enlargement, in-situ pulmonary artery thrombosis, and respiratory tract infection were found to be independent clinical factors related with CRD in PTE patients. CRD was an independent predictors of PTE-related in-hospital death. Conclusions: Patients with PTE and concomitant CRD are associated with a lower incidence of unprovoked PTE and higher incidences of PESI class IV-V, pulmonary artery enlargement, in-situ pulmonary artery thrombosis, and respiratory tract infection. PTE patients with CRD had a significantly higher PTE-related in-hospital mortality than those without CRD.

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