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증례 : Sildenafil 치료로 성공적으로 출산한 문맥성 폐동맥고혈압(Portopulmonary Hypertension) 1예
민희석 ( Hee Suk Min ),장혁재 ( Hyuk Jae Chang ),조영석 ( Yong Seok Cho ),연태진 ( Tae Jin Youn ),정우영 ( Woo Young Chung ),채인호 ( In Ho Chae ),최동주 ( Dong Ju Choi ) 대한내과학회 2007 대한내과학회지 Vol.73 No.2
저자들은 문맥성 폐동맥고혈압을 가진 임산부에서 Phosphodiesterase V 억제제인 sildenafil 치료로 성공적인 출산을 한 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. The mortality of pulmonary hypertension that complicates pregnancy is very high. The increased pulmonary vascular resistance combined with the normal physiological changes of pregnancy and delivery is difficult to manage. We describe here the case of a pregnant woman who presented with severe portopulmonary hypertension. A 30-yr-old woman presented with dyspnea at 8 weeks of pregnancy. The mean pulmonary artery pressures (PAP), as measured from a pulmonary artery catheter at 20 weeks gestation, were 71 mmHg. Sildenafil was used to reduce the PAP for 4 months. She responded to sildenafil therapy and successfully completed her pregnancy.(Korean J Med 73:200-205, 2007)
급성 A형 간염 환자에서 발생한 간질성 신염과 IgA 신병증의 병발에 의한 급성 신부전 : 1예 보고
한승석 ( Seung Seok Han ),김민경 ( Min Kyung Kim ),최병용 ( Byoung Yong Choi ),민희석 ( Hee Suk Min ),김학령 ( Hack Lyoung Kim ),정용진 ( Chun Soo Lim ),임춘수 ( Chun Soo Lim ),이현주 ( Hyun Ju Lee ),문경철 ( Kyung Chul Moon ) 대한신장학회 2007 Kidney Research and Clinical Practice Vol.26 No.6
윤효은 ( Yoon Hyo Eun ),황보주 ( Hwang Bo Ju ),석웅 ( Seng Woong ),민희석 ( Min Hee Suk ) 국군의무사령부 2010 대한군진의학학술지 Vol.41 No.1
Objective: Yellow fever, a mosquito-borne viral hemorrhagic fever, is one of the most lethal diseases. Recently Korea raise nation's states to a higher level by hosting G20 SEOUL SUMMIT 2010. And Korea sends troops overseas such as Peace keeping operation(PKO) to contribute to world peace. Therefore, we carried out this study to provide Overseas dispatch soldiers information about Yellow Fever Vaccine(YFV). Method: This study was conducted at the OO clinic between June 7 to June 24, 2010, for the evaluation of adverse events of YFV. Eighty-three healthy adults were vaccinated YFV(17-DD) and were prospectively monitored for adverse events through questionnaire to July 23, 2010, after YFV vaccination. Results: Adverse events were observed in 41(49.4%) of 83 adults who were vaccinated YFV. Sixty-four of the adults(77.1%) were males. The mean age was 38.2±8.2 years. The common adverse events were myalgia in 28(33.7%), Chilling sense in 25(30.1%), Headache in 21(25.3%). There were no differences of adverse events according to gender or age. Most adverse events were developed between 4~9days after YFV injection. Conclusion: This study showed that adverse events by YFV have a higher incidence and delayed onset time than Influenza Vaccine. Studies are ongoing to clarify the cause and risk factors for rare adverse events.