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Dilantin Sodium 投與로 因한 口腔粘膜 肥大症의 臨床 및 實驗的 硏究
文東先 최신의학사 1970 最新醫學 Vol.13 No.2
After subcutaneous injections of 100mg/kg body weight of dilantin sodium to rats, the author observed following results. 1) Keratinization of oral mucous epithelium was highly increased. 2) Connective tissue of oral mucosa showed elevated fibroblastic activity with pronounced collagen fiber formation. 3) Histochemical staining reactions suggested a substitution of glycoproteins for mucopolysaccharides staining material in the connective tissue was noted. 4) Increase in the glycoproteins and mucopolysaccharides staining material in the connective tissue was noted.