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면역기능이 정상인 환자에서 저용량 스테로이드를 복용 후 발생한 폐 효모균증 1례
장나은 ( Na Eun Jang ),신아리 ( A Ri Shin ),김혁 ( Hyuck Kim ),이정훈 ( Jung Hoon Lee ),조주희 ( Joo Hee Cho ),고원진 ( Weon Jin Ko ),김태영 ( Tae Young Kim ),김이형 ( Ee Hyung Kim ),유지홍 ( Jee Hong Yoo ),박명재 ( Myung Jae Par 전북대학교 의과학연구소 2012 全北醫大論文集 Vol.36 No.2
Cryptococcus neoformans is an organism that mainly causes opportunistic infection in immunocompromised patients. It can also cause various infections in immunocompetent patients including pulmonary cryptococcosis, but it is rare. Steroids are used in clinical practice for treatment of a wide array of disease, because of their anti-inflammatory or immunosuppressive action. But, steroids use predisposes patients to a variety of infection by interfering with host defense mechanism. Infections associated with steroids are dependent on the route of administration, dose, and duration of therapy. Generally, the rate of infection is not increased in patients receiving low dose and limiting periods administration. We presented a case of pulmonary cryptococcosis obscured by cryptogenic organizing pneumonia (COP) in 68-year old female with an immunocompetent patient after low dose and short duration of steroid therapy and review all published casese.