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한국 중년여성에서 내장지방 축적이 당질 대사에 미치는 영향
허갑범 ( Heo Gab Beom ),안광진 ( An Gwang Jin ),이현철 ( Lee Hyeon Cheol ),임승길 ( Im Seung Gil ),이영해 ( Lee Yeong Hae ),이종호 ( Lee Jong Ho ),김명중 ( Kim Myeong Jung ),백인경 ( Baeg In Gyeong ),박유경 ( Park Yu Gyeong ),이 대한내과학회 1993 대한내과학회지 Vol.44 No.5
연구배경 : 한국인에서는 비만의 정도가 서구인에서 보다 아직은 낮을지라도 지방분포 측면으로 볼 때 중심성 비만을 보일지라도 컴퓨터 단층촬영상 내장형 비만일 경우 대사질환과 더 밀접한 관련이 있을 것이다. 본 연구는 건강한 55예의 중년여성들의 자발적인 참여로 한국중년여성에서 비만의 형태가 당질대상 미치는 영향을 연구하였다. 방법 : 비만의 지표로 허리와 엉덩이 둘레비율, 체질량지수(BMI), 표준체중백분율(PIBW)과 컴퓨터 단층촬영을 통한 내장지방 면적, 피하지방 면적 등을 측정하였다. 혈압, 식품섭취량과 하루 필요열량을 조사하였으며 내당능 검사를 시행하여 포도당, 인슐린, C-petide, 유리지방산 농도를 분석하였다. 또한 중성지방 LDL, HDL, total cholesterol도 분석하였다. 결과 : 비만의 지표들 중 내장지방 면적이 혈압, 혈청지질과 당부하 검사치들과 가장 많은 상관성을 보여주었다. 내장지방 면적이 10000㎜² 이상인 20예의 내장형 비만군에서 7400㎜² 이하인 18예의 피하형 비만형 비만군과 비교하여 나이, 체중, PIBW, BMI, % body fat이 비슷한데도 불구하고 혈청 중성지방, 공복 및 당부하시기 유리지방산, 당, 인슐린, C-peptide의 농도들이 보여졌으며 필요열량보다 과다한 열량을 섭취하는 것으로 나타났다. 내장형 비만인들이라도 당질대사의 이상을 보여주는 경우 당질대사가 정산인 경우와 비교하여 내장지방 면적은 비슷하면서 체중과 피하지방 면적의 감소, 당부하시 유리지방산과 당 면적의 증가와 인슐린과 C-peptide 면적의 감소를 보여주었으며 열량섭취와 필요열량의 비율이 많은 것으로 나타났다. 결론 : 이상의 결과들은 내장형 비만인에서 인슐린 분비능의 경미한 감소는 심한 인슐린 저항으로 인해 당뇨병을 유발할 수 있다는 것을 보여주었다. 또한 1일 필요열량과 비교하여 과잉된 열량의 섭취가 내장형 비만의 부분적인 이유라는 것을 알 수 있었다. Backgrounds: Although Koreans are generally leaner than people in America, they have a tendency to central adipose tissue distribution. Central obesity with visceral fat accumulation, measured by computed tomography, can cause metabolic complications. We determined the relation between obesity and glucose metabolism in 55 Korean middle-aged women. Methods: Anthropometric parameters and visceral and subcutaneous fat areas at the umbilical level were determined as indices of obesity. Nutrient intake, serum levles of lipids and response areas of glucose, C-peptide, insulin, and free fatty acid (FFA) during oral glucose tolerance test were determineds. Results: Visceral fat area correlated the most significantly with biochemical parameters among obese indices. The triglyceride level and the response area of FFA, glucose, insulin and C-peptide were all higher in the group of visceral-type obesity (n=20, visceral fat area>10000 mm²), than in the group of subcutaneous-type obesity (n=18, visceral fat area<7400 mm²), though percent ideal body weight was not different between two groups. Thirty five percents in the group of visceral-type obesity showed impaired glucose tolerance (IGT) and non-insulin-dependent diabeyts mellitus (NIDDM). Body weight, subcutaneous fat area and the response areas of insulin and C-peptide were lower and the response areas of FFA and glucose were higher in visceral-type obese patients with IGT and NIDDM thatn in visceral-type obese subjects with normal glucose tolerance. Conclusions: Our results indicate that increased visceral fat area can be associated with the development of NIDDM because of the severe insulin resistance, even when small amonunt of insulin secretion in decreased. Increased calorie intake and decrease physical activity could partly explain visceral fat accumulation in the intraabdominal cabity.
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마이크로 프로세서를 사용한 전동기의 속도제어에 관한 연구
김명중 忠州大學校 1982 한국교통대학교 논문집 Vol.15 No.1
The writer studied a way of speed control on DC motor using the microprocessor. The main control system consists of encoder for speed detection, MC 6802 microprocessor and D/A converter to processor erros correction. To attain required speed, the writer compared measured speed with set speed, and controlled armature voltage of motor through D/A converter and servo amplifier. Microprocessor based speed control was supported by soft ware programs and programmed speed control could easily be performed by changing required input data. As the result of speed control, the writer was able to reduced the steady state to less than 0.5% of set speed.
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Microprocessor 를 使用한 波形 發生回路의 設計
金明中 忠州大學校 1983 한국교통대학교 논문집 Vol.16 No.2
This paper, microprocessor are used to design a waveform generator. I can be used in the field of electronic measurement and automatic control system. This waveform generator produce a waveform which we want and adjust easily initial and terminal point. Frequency range which can be generate waveforms are about 1 KHz by the program control and are about 10 KHz by the DMA method. Expecially this waveform generator are useful to generate a various waveform in the low-frequency range.
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MSI(TTL)를 이용한 교육용 마이크로프로세서의 설계
김명중 忠州大學校 1984 한국교통대학교 논문집 Vol.17 No.2
A microprocessor can be accumulated in a LSI and the accumulation is improving rapidly with the development of semi-conductor techniques. In the case of students who didn't get used to LSI, however, they may have difficulties in understanding the structure and the operation of microprocessor in proportion to improving the accmulation. Another reason for students not to understand the microprocessor is that they may get used to wired logic through the general digital circuit, but not program logic. Accordingly this paper tried to present a method of designing the microprocessor by wired logic for the practical education. For our purpose the writer set up a small model to handle 4 bits data and designed it using MSI. The writer confirmed the operation through experiments.
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光 多變色 迷路裝置에 의한 초파리의 光鮮好性 差異에 관한 遺傳學的 硏究
金明仲,朴殷圭,崔五木 圓光大學校 基礎自然科學硏究所 1989 基礎科學硏究誌 Vol.8 No.2
The present experiments for positive and negative walking behavior were carried out with the popula-tions of Drosophila melanogaster, collected from eight localities of the Korean peninsula. The behavior was examined by means of photo-varicolored ladyrinth apparatus. The realized heritabi-lity for males on difference in photo-preference was estimated to the about 3.4∼9.4% for the positivewalking behavior, and that for negative behavior was about 4.2~8.6% . The heritability for femaleswas estimated to be about 1.0∼12.6% for the positive walking behavior, and that for negative behaviorwas about 2.4∼9.5%. Walking score for males and females in inland was estimated to be about 2,00~3,00 for the positivewalking behavior, and that for negative behavior was about 1,00∼1.25. Walking score for males and females on the coast was estimated to be about 2.25~2.90 for the positivewalking behavior, and that for negative behavior was about 1.16∼1.50. In conclusion, the walking behavior of photo-varicolored preference showed that it prefered bluelight color best, second; yellow, third; red, and last; dark. It seems resonable to assume that thewalking behavior is possibly controlled by a major gene.
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