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현준원(June Won Hyun),윤미영(Mi Young Yun),안상민(S. M. An),노승정(S. J. Noh),허영덕(Young-Duk Huh),박헌용(Heonyong Park),송예신(Y. S. Song),피재호(Jaeho Pyee),김경례(K. R. Kim),김성훈(H. S. Kim) 한국표면공학회 2004 한국표면공학회지 Vol.37 No.2
Nickel chloride coated protein chip plate was developed by using a spin coating method. The ability of histidine tagged protein adsorption was investigated at various solvents. The surface of plate has a large aggregated nickel complex with high density in water. However, the surface of plate has a very small size of aggregated nickel complex with low density in isopropanol. The ability of protein adsorption decreased as increasing the size of alkyl chain in various alcohol solvents. The mechanism on the ability of protein adsorption at the plate surface is discussed.