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- 저자 : ( Osung Kown ) (검색결과 2 건)
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A case of follicular B cell lymphoma
( Hyungrok Kim ),( Osung Kown ),( Hyunjung Kwon ),( Youngil Kim ),( Kyungduck Park ),( Hyun Chung ),( Joonsoo Park ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
Follicular lymphoma is the most common indolent form of B cell lymphoma, accounting for approximately 20 percent to 30 percent of all non-Hodgkin lymphomas. Less than 5 percent of the patients have skin involvement at the time of diagnosis. A 55-year-old woman presented with multiple erythematous pruritic papules and plaques on her face and scalp for 1 year. She had no family history of skin diseases. She applied topical steroid agent but the lesion showed poor clinical outcome. The biopsy specimen on her scalp showed tumor cells composed of small to medium-sized cleaved cells (centrocytes) and large non-cleaved cells (centroblasts). In immunohistochemical analysis, the tumor cells were positive for CD 20, CD10, Bcl-2, Bcl-6 and negative for CD3. Computed tomography imaging of the neck and chest showed an increased density in the supraclavicular lymph node. Based on these clinical, histophatological and radiological findings, the patient was diagnosed of disseminated follicular lymphoma. Herein, we report a case of follicular lymphoma diagnosed in skin biopsy, in which cutaneous lesion was the first sign of internal malignancy.
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A case of verrucous carcinoma masquerading as verruca
( Hyungrok Kim ),( Osung Kown ),( Hyunjung Kwon ),( Youngil Kim ),( Kyungduck Park ),( Hyun Chung ),( Joonsoo Park ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
Verrucous carcinoma is a rare variant type of well differentiated squamous cell carcinoma with low-grade malignancy, slow growth, and little metastatic potential. These lesions are mostly found in the oral mucosa. The special feature of verrucous carcinoma is that it appears macroscopically malignant but histologically more benign. A 59-year-old man presented with a whitish, 1 cm sized plaque on left lower lip. He had no medical history, and there was no family history of skin diseases. The biopsy specimen of his left lower lip showed hyperkeratosis, endophytic acanthosis of epidermis and diffuse infiltration of lymphocytes on upper dermis. The initial diagnosis was verruca and we performed cryotherapy for 3 times. However, 3 months later, his lesion was bigger in size and characteristic of a bleeding ulcer. We performed biopsy again, and diagnosed as verrucous carcinoma. The lesion was excised and the exposed area was skin grafted. Herein, we report a case of verrucous carcinoma masquerading as verruca. Wider recognition of the condition is needed among the dermatologists to prevent delayed diagnosis.
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