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      • Clinical characteristics of females with chronic obstructive pulmonary disease in Korea

        ( Shinyoung Kim ),( Hyoungkyu Yoon ),( Chinkook Rhee ),( Yong Hyun Kim ),( Jin Hwa Lee ),( Ki Uk Kim ),( Ki Suck Jung ),( Kwang Ha Yoo ) 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-

        Tobacco smoking is established as a major risk factor of COPD. Over the years COPD has been considered as disease in men, however, the number of female COPD is increasing, especially in developing countries. The clinical characteristics of female COPD patients are not well known, particularly in Asia. We investigated the clinical characteristics of female COPD patients with large Korean COPD cohort. We analyzed the data from the Korea COPD Subgroup Study Cohort Study, whichis a multicenter observational study that includes 1662 patients who were enrolled from 45 tertiary and university-affiliated hospitals from December 2011 to October 2014. A total of 1662 patients were included in this study, 146 (8.8%) were females and 1516 (91.2%) were males. Females were less likely to be smoker, and shown to have more exposure to passive smoking and more exposure to biomass. Bronchiectasis and respiratory infection in childhood also appeared significantly higher infemale COPD, indicating that these also affected female COPD occurrence. Depression was significantly more common in female COPD. Although it was not statistically significant, severe exacerbations occurred frequently in female COPD patients, and the rate of lung function decline also tended to be faster in female COPD.The mMRC score, SGRQ-C score and CAT score of females were significantly higher than males respectively. Female COPD patients were more likely to report activity limitations, sleep disturbances and energy shortages. Female COPD patients were shown to higher FEV1% pred. and FEV1/FVC % than in male patients. Passive smoking, exposure to biomass, bronchiectasis and respiratory infection in childhood are judged to be important causative factors in female COPD patients. Severe exacerbations and rate of decline tended to higher in female COPD. In addition, the incidence of depression were high on female COPD and respiratory symptoms were more severe in female COPD.

      • KCI등재

        항공기엔진용 1단계 터빈블레이드에 대한 파손 연구

        윤영웅(Youngwoung Yoon),박형규(Hyoungkyu Park),김정(Jeong Kim) 한국항공우주학회 2018 韓國航空宇宙學會誌 Vol.46 No.10

        항공기 엔진을 구성하는 부품 중 하나인 블레이드의 파손에 대해 분석하였다. 블레이드의 파손원인과 그 거동은 다양하지만 크게 일시파단과 피로파손의 두가지 형태로 나뉘어진다. 이 논문에서는 전체 거동은 일시파단으로 진행되고 일부 피로 파손된 블레이드에 대해 기술하였고, 특히 고온에서의 블레이드 손상거동을 분석하므로써 사례의 하나로 제하고자 한다. 분석한 블레이드는 니켈기 초내열 합금으로 외관, 재질, 미세조직, 고온 크리프 특성, 파단면 형상을 각각의 분석장비를 활용하여 손상원인과 거동을 확인하였고, 원재질에서 재현되었다. 고온에서 니켈 합금은 γ형상이 변형되고 조직변형과(Alloy Depletion)구간이 관찰되며 재질의 기계적 성질, 물성치 등이 저하되고 연화되어 장시간 운용 시 파손될 수 있다. 니켈합금은 고온특성이 좋으나 함유되는 미량원소에 따라 그 물성치가 다양하므로 니켈합금이라 하여도 그 목적에 맞는 세분화된 소재를 사용해야한다. The fracture of a turbine blade of aerospace engine is presented. Although there are a lot of causes and failure modes in blades, the main failure modes are two ways that fracture and fatigue. Degradation of blade material affects most failure modes. Total Propagation of failure in this study specifies failure of fracture type. Some section appears fatigue mode. Especially since this study describes analysis of failure for blade in high temperature, it can be a case in point. Analysed blade is Ni super alloy. Investigations of blade are visual inspection, material, microstructure, high temperature stress rupture creep test, analysis and fracture surface, etc. The root cause for fracture was stress rupture due to abnormal thermal environment. Thermal property of Ni super alloy is excellent but of each chemical composition of alloys are different due to change mechanical properties, selection of material is very important.

      • CT interpretation based strategy for asbestos related lung cancer

        ( Jun-pyo Myong ),( Jungim Jung ),( Hyoungkyu Yoon ) 대한결핵 및 호흡기학회 2018 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.126 No.-

        The asbestos can result in various health outcomes such as asbestosis, malignant mesothelioma, lung cancer, and etc. However, the numbers of asbestos related health outcomes may be underestimated in Korea. The aim of this study is to establish a surveillance program for hidden asbestos related lung cancer (ARLC) and evaluate the effect of surveillance program. A total of 7 hospitals joined to find a hidden ARLC in this active surveillance program. The reading sheet of chest CT scan among incident lung cancer in all hospitals were collected for retrospective evaluation (2015.07-2017.06) and a prospective evaluation have been performed for 6 months (2017.07-2017.12). The searching keywords in the reading sheet of chest CT scan for asbestos exposure were ‘plaque’, ‘asbestos’, ‘asbestosis’. A total of 5,389 (No of CT scan=17,503) those who eligible subjects diagnosed as incident lung cancer in retrospective evaluation and 2,030 (No of CT scan=2,976) those diagnosed as incident lung cancer in prospective evaluation were enrolled. The numbers of those subjects with lung cancer who are estimated the exposure of asbestos were 29 cases (7.2 cases per 6 months) in retrospective evaluation and 12 cases per 6 months in prospective evaluation, respectively. Overall increase of finding ARLC (0.54% → 0.98%) after informing process for radiologist was shown. This study result shows that the national statistics of ARLC may be underestimated. In addition, a hospital-based surveillance program focused on radiologists will make the numbers of reporting the ARLC increase.

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