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Hwang, Hun-Gyu,Lee, Ho-Sung,Choi, Jae-Sung,Seo, Ki-Hyun,Kim, Yong-Hoon,Na, Ju-Ock The Korean Academy of Tuberculosis and Respiratory 2013 Tuberculosis and Respiratory Diseases Vol.74 No.3
Background: Hemoptysis due to pulmonary tuberculosis (TB) frequently develops in Korea where the prevalence of TB is intermediate. The effect of bronchial artery embolization (BAE) on the control of massive hemoptysis has been well known. This study is designed to identify the risk factors contributing to rebleeding after BAE in patients with TB. Methods: We retrospectively evaluated risk factors and the time for rebleeding after BAE in 72 patients presenting with hemoptysis. Results: The overall immediate success rate of BAE was 93.1% (67 of 72 patients). Of the 29 patients (40.3%) who showed rebleeding after BAE, 13 patients experienced rebleeding within 1 month, and 14 patients between 1 month to 1 year. The existence of a shunt in angiographic finding, aspergilloma, and diabetes mellitus were risk factors of rebleeding after BAE in multivariate analysis. Conclusion: BAE was very effective for obtaining immediate bleeding control in hemoptysis associated with active TB or post-TB sequelae. It is important to observe whether or not rebleeding occurs up to 1 year of BAE especially in TB patients with aspergilloma, DM, or a shunt. Even rebleeding can be managed well by second BAE.
ISO 19848 데이터 채널 표현과 선박 기관장비 고장·유지보수 유형 관리를 위한 코드화 기법
Hwang, Hun-Gyu,Woo, Yun-Tae,Kim, Bae-Sung,Shin, Il-Sik,Lee, Jang-Se 한국정보통신학회 2020 한국정보통신학회논문지 Vol.24 No.1
Recently, there are emphasized to support the maintenance and management system of vessels using acquired data from engine part equipment. But, there are limitations for data exchange and management. To solve the problem, the ISO published ISO 19847 and 19848. In this paper, we analyze the ISO 19848 requirements related to identify data channel ID for ship equipment, and propose the examples for applying encoding techniques. In addition, we suggest the proposed technique for applying of managing the failure and maintenance type of the ship's engine part facilities by examples. If this method is applied, the vessel's equipment can exchange data through the sharing of the code table, and express what response is needed or acted, including where the failure occurred.
Respiratory Review of 2013: Pulmonary Thromboembolism
Hwang, Hun Gyu,Schulman, Sam The Korean Academy of Tuberculosis and Respiratory 2013 Tuberculosis and Respiratory Diseases Vol.75 No.3
Pulmonary embolism (PE), which can originate as a consequence of deep vein thrombosis (DVT), is the most frequent and potentially fatal venous thromboembolic event. Despite the fact that the incidence of venous thromboembolism (VTE) in Asians is lower than that in the Western populations, a recent epidemiologic study demonstrates an increasing incidence of VTE in the Korean population. Anticoagulants, including low molecular weight heparin (LMWH) and vitamin K antagonist (VKAs), have been the main treatments for PE, however, recently new oral anticoagulants (NOACs) were introduced. We will review how well patients with PE can be managed with the existing anticoagulants and NOACs along with the time span of treatment, which still pose some challenges for clinicians.
( Hun-gyu Hwang ),( Soo-mee Bang ),( Ju Hyun Lee ),( Sang-a Kim ),( Yang-ki Kim ),( Ho-young Yhim ),( Junshik Hong ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-
Background and aim The rate of venous thromboembolism (VTE) has gradually increased within the Korean population. This third nationwide population-based epidemiologic study aims to evaluate the annual age- and sex- and sex-adjusted rates (ASR) of VTE and anticoagulation trend between 2014 and 2018. Methods Using the Korean Health Insurance Review and Assessment Service database, we retrospectively identified VTE patients between 2014 and 2018 by using both diagnostic and medication anticoagulant codes assigned within six months of the initial index event. Patterns of anticoagulants were classified as follows: DOAC-based regimen; UFH and/or LMWH regimen; warfarin-based regimen; and mixed anticoagulation regimen. Results We identified 95,205 individuals with VTE (54,085 female, 56.8%). The ASR for VTE per 100,000 person-years increased from 32.8 in 2014 to 53.7 cases in 2018 (relative risk of 1.63; 95% CI, 1.6 to 1.67; p-value < 0.0001) (Figure 1). The VTE incidence rates are 25 times higher in the 80 or older group than the 30s group. The VTE in females occurred 1.29 times more often than males. The proportion of DOAC-based prescription increased from 40.5% to 72.8%, whereas warfarin-based prescription from 27% to 5.6% in 2014 and 2018. Conclusion In Korea, ASRs of VTE continued to increase since 2014, but the rate of increase has slowed in 2018. The VTE incidence rate are higher in elderly group than the middle-aged group. The VTE in females occurred more often than males. Five years after DOACs were introduced in 2013, they account for 73% of all anticoagulants used to treat VTE.
Review : Respiratory Review of 2013; Pulmonary Thromboembolism
( Hun Gyu Hwang ),( Sam Schul Man ) 대한결핵 및 호흡기학회 2013 Tuberculosis and Respiratory Diseases Vol.75 No.3
Pulmonary embolism (PE), which can originate as a consequence of deep vein thrombosis (DVT), is the most frequent and potentially fatal venous thromboembolic event. Despite the fact that the incidence of venous thromboembolism (VTE) in Asians is lower than that in the Western populations, a recent epidemiologic study demonstrates an increasing incidence of VTE in the Korean population. Anticoagulants, including low molecular weight heparin (LMWH) and vitamin K antagonist (VKAs), have been the main treatments for PE, however, recently new oral anticoagulants (NOACs) were introduced. We will review how well patients with PE can be managed with the existing anticoagulants and NOACs along with the time span of treatment, which still pose some challenges for clinicians.
Incidence and Risk Factors of Recurrent Venous Thromboembolism after Pulmonary Embolism
Hwang, Hun-Gyu,Choi, Won-Il,Lee, Bora,Lee, Choong Won The Korean Academy of Tuberculosis and Respiratory 2019 Tuberculosis and Respiratory Diseases Vol.82 No.4
Background: Information about the epidemiology of venous thromboembolism (VTE) recurrence in Korea is lacking. The purpose of this study was to investigate VTE cumulative recurrence rates and identify risk factors for VTE recurrence among Korean adults. Methods: A retrospective cohort study was conducted on adult patients (${\geq}18years$) admitted to a university teaching hospital for pulmonary embolism (PE) from 2005 to 2013. The main outcome of interest was a recurrence of VTE. We used Cox proportional hazard regression analyses to calculate the relative risk of VTE recurrence. Results: Five-year cumulative incidence of recurrent VTE events was 21.5% (95% confidence interval [CI], 17.7-25.4) in all cases of PE; 17% after provoked and 27% after unprovoked PE. Multivariate analysis showed that body mass index (BMI) of ${\geq}25$ (hazard ratio [HR], 2.02; 95% CI, 1.17-3.46; p=0.01) and longer anticoagulation therapy duration (HR, 0.90; 95% CI, 0.84-0.96; p<0.01) were independently associated with risk of VTE recurrence. Risk factors not found to be statistically significant at the <0.05 level included history of VTE (HR, 1.81; 95% CI, 0.84-3.88; p=0.12), unprovoked PE (HR, 1.70; 95% CI, 0.89-3.25; p=0.10), symptomatic deep vein thrombosis (HR, 1.62; 95% CI, 0.89-2.94; p=0.10), and female sex (HR, 1.42; 95% CI, 0.78-2.55; p=0.24). We found that age, history of cancer, and other co-morbidities did not significantly affect the risk of VTE recurrence. Conclusion: Recurrence of VTE after PE is high. Patients with BMI ${\geq}25$ or reduced anticoagulation therapy duration have a higher risk of recurrent VTE.
Incidence and Risk Factors of Recurrent Venous Thromboembolism after Pulmonary Embolism
( Hun-gyu Hwang ),( Won-il Choi ),( Bora Lee ),( Choong Won Lee ) 대한결핵 및 호흡기학회 2019 Tuberculosis and Respiratory Diseases Vol.82 No.4
Background: Information about the epidemiology of venous thromboembolism (VTE) recurrence in Korea is lacking. The purpose of this study was to investigate VTE cumulative recurrence rates and identify risk factors for VTE recurrence among Korean adults. Methods: A retrospective cohort study was conducted on adult patients (≥18 years) admitted to a university teaching hospital for pulmonary embolism (PE) from 2005 to 2013. The main outcome of interest was a recurrence of VTE. We used Cox proportional hazard regression analyses to calculate the relative risk of VTE recurrence. Results: Five-year cumulative incidence of recurrent VTE events was 21.5% (95% confidence interval [CI], 17.7-25.4) in all cases of PE; 17% after provoked and 27% after unprovoked PE. Multivariate analysis showed that body mass index (BMI) of ≥25 (hazard ratio [HR], 2.02; 95% CI, 1.17-3.46; p=0.01) and longer anticoagulation therapy duration (HR, 0.90; 95% CI, 0.84-0.96; p<0.01) were independently associated with risk of VTE recurrence. Risk factors not found to be statistically significant at the <0.05 level included history of VTE (HR, 1.81; 95% CI, 0.84-3.88; p=0.12), unprovoked PE (HR, 1.70; 95% CI, 0.89-3.25; p=0.10), symptomatic deep vein thrombosis (HR, 1.62; 95% CI, 0.89-2.94; p=0.10), and female sex (HR, 1.42; 95% CI, 0.78-2.55; p=0.24). We found that age, history of cancer, and other co-morbidities did not significantly affect the risk of VTE recurrence. Conclusion: Recurrence of VTE after PE is high. Patients with BMI ≥25 or reduced anticoagulation therapy duration have a higher risk of recurrent VTE.