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Calcaneal quantitative ultrasound analysis in korean and japanese elite female athletes
송홍선,민석기,Hideaki Ishigami,이기혁,Harlisa Rozikin,Koichi Nakazato 국민체육진흥공단 한국스포츠정책과학원 2017 International Journal of Applied Sports Sciences Vol.29 No.2
The relationships between bone properties and cumulative mechanical impact were examined in elite female athletes (N=70) and age, gender matched non-athlete controls (N=64). The athletes were divided into 3 groups, namely, high-impact (HI: body weight bearing with high mechanical loading, N=18), medium-impact (MI: body weight bearing with medium load, N=36), and low-impact (LI: body weight bearing with low load, N=16). Effects of mechanical impact on quantitative ultrasonography (QUS) parameters, including speed of sound (SOS), broadband ultrasound attenuation (BUA), and stiffness index (SI), were assessed using a multiple linear regression model adjusted for age, body weight, height, body mass index, and impact. We found that BUA was positively influenced by MI (P < 0.05). SOS was negatively influenced by LI (P < 0.05). SI was positively influenced by MI (P < 0.05). In conclusion, the bone qualities in elite female athletes differ depending on their cumulative impacts.
( Kenichiro Okimoto ),( Makoto Arai ),( Hideaki Ishigami ),( Keiko Saito ),( Shoko Minemura ),( Daisuke Maruoka ),( Tomoaki Matsumura ),( Tomoo Nakagawa ),( Tatsuro Katsuno ),( Masaki Suzuki ),( Yukio 대한간학회 2018 Gut and Liver Vol.12 No.1
Background/Aims: Eosinophilic esophagitis (EoE) is often erroneously diagnosed as gastroesophageal reflux disease (GERD). The aim of this study is to investigate the prevalence of EoE and the expression of tight junction (TJ) proteins in patients with GERD symptoms. Methods: One hundred patients with GERD symptoms and 10 healthy controls were prospectively studied. Sixty-two patients had symptoms refractory to proton pump inhibitors (PPI). All patients underwent esophageal biopsy. Patients were diagnosed with EoE if the number of eosinophil granulocytes per high-power field was ≥15. Immunohistochemical analysis of TJ proteins (claudin-1, claudin-4, occludin, and zonula occludin-1 [ZO-1]) was performed. Results: EoE was diagnosed in six of 100 patients (6%) with GERD symptoms and in six patients (9.7%) of 62 patients with PPI-refractory GERD. Only one had typical EoE endoscopic findings. The proportion of ZO-1-positive cells was significantly lower in the lower than in the middle esophagus (56.0%±14.0% vs 66.0%±11.5%, p<0.05). There were no significant correlations between TJ protein expression and GERD symptoms. Conclusions: The prevalence of EoE among patients with PPI-refractory GERD is approximately 10%. Regardless of endoscopic findings, esophageal biopsy is crucial in diagnosing EoE. The disruption of ZO-1 expression in the lower esophagus is significantly associated with GERD symptoms. (Gut Liver 2018;12:30-37)