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정신건강의학과 외래에서의 벤조디아제핀계 향정신성의약품 처방간격 관련요인 분석
심재환(Jae-hwan Sim),한지연(Ji Yeon Han),전진용(Jin-yong Jun),전명욱(Myong-Wuk Chon) 한국중독정신의학회 2021 중독정신의학 Vol.25 No.1
Objective : This study investigated the factors affecting the prescription interval of benzodiazepines and related psychotropics. Methods : The prescription intervals were extracted from all patients (n=1873) who visited the outpatient department of a single psychiatric hospital for one month in June 2019, and the potential factors related to longer psychotropic prescription were explored. Logistic regression analysis was performed to assess the relationship between the potential risk factors and the length of psychotropic medication prescription in days. Results : Two cutoff values (30 days and 35 days) were used for the appropriate prescription interval. Older age [cutoff 30 days, Exp(B)= 1.014, p=0.001 ; cutoff 35 days, Exp(B)=1.014, p=0.001], fewer number of admissions [30 days, Exp(B)=0.459, p<0.001; 35 days, Exp(B)=0.438, p<0.001], fewer number of treatment sessions [30 days, Exp(B)=0.894, p<0.001; 35 days, Exp(B)=0.899, p<0.001], and longer duration of treatment [30 days, Exp(B)=1.022, p= 0.004 ; 35 days, Exp(B)=1.024, p=0.001] were related to a longer prescription interval of psychotropics. Longer duration of illness [30 days, Exp(B)=1.017, p=0.017] was related to a longer prescription term and on-site reception compared to reservation [35 days, Exp(B)=0.585, p=0.022] with a shorter prescription term. Conclusion : Our results suggest that the elderly and patients with a longer duration of illness need closer monitoring for long-interval prescription of benzodiazepines and related psychotropics.
배연미,이미경,윤일순,이영미,주수만,송보완,김종우,홍남두 한국병원약사회 1992 병원약사회지 Vol.9 No.2
The purpose of this study is to assist the management of psychotropic drugs and inspection of the prescription on preparing a medicine. The range of investigation is the data of 6,445(29%) prescriptions involving the psychotropic drugs among the total 22,233 prescriptions of outpatients from August 1st to August 31th, 1991. In analyzing method we classified the number of prescriptions, distribution of sex, age, clinical department, disease, kinds of prescribed drugs, and prescribing frequency through these 6,445 prescriptions. The result of study were as follows : The sex distribution showed 59% and 41% in female and male. The age distribution were most in 50'age. The distribution by clinical department listed the internal medicine(51.9%), neuropsychiatry(17.8%) and neurosurgery(12.8%) in descending oryder. The rated of each disease were 33%, 17%, 15% and 10% for circulatory disease, mental disorder, digestive disease and nervous disease. The prescribing frequency of psychotropic drugs listed the diazepam(26.8%), lorazepam(15.6%), phenobarbital(11.6%) and clobazam(9.6%) in descending order. The above results showed that the most frequency in Psychotropic drugs were benzodiazepines(21%), Therefore the usage of a vast range in psychotropic drugs Suggests possibility of iatrogenic drug abuse. Also this serious problems must be considered of that a uniform prescribing tendency of partial benzodiazepines and preferring tendency of specific drugs in specific department showed.