http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Development and Evaluation of a Novel Inclusion Seeding Methodology for Ti-6Al-4V Castings
( Paul L. Ret ),( Jerald R. Brevick ),( Yong K. Park ) 대한금속재료학회 ( 구 대한금속학회 ) 2007 METALS AND MATERIALS International Vol.13 No.4
Hard alpha inclusions in titanium (Ti) investment castings are generally known to have detrimental effects on the mechanical properties of these castings. However, actual inclusions are infrequent and occur in random locations in castings. As a result, it is difficult to obtain tensile or fatigue test specimens of titanium castings with inclusions in the gage section. Quantifying the adverse influence of inclusions on the mechanical properties of castings is, therefore, extremely challenging. To address this problem, a novel artificial inclusion seeding methodology was developed to emulate actual Ti investment casting inclusions. Prefabricated inclusions were seeded into machined holes in cast Ti-6Al-4V plates, the holes were back-filled with plugs of the same Ti alloy and were then electron-beam (EB) welded closed. Hot isostatic pressing (HIP) was utilized to incorporate the inclusions fully into the cast titanium material. Finally, the plates were machined to create mechanical test specimens with inclusions centered in the gage region. Test specimens created by means of this novel artificial seeding methodology were evaluated and found to be equivalent to Ti casting specimens containing actual cast-in inclusions.
홍은경,김해리 ( Eun Kyung Hong,Har Ret Kim ) 생화학분자생물학회 1984 BMB Reports Vol.17 No.4
It was reported that the opiate peptides function as a neurotransmitter of neuromodulator. They may be involved in a natural pain suppression system (analgesia) or possibly also in other behavioral and emotional functions and food intake regulation. In the present study, the changes of opiate receptor binding in the whole brain, cortex, cerebellum, hypothalamus, midbrain, medulla oblongata, striatum, pylorus and ileum, from the 18th day of gestation to adulthood in both sexes were investigated. We observed that the developmental pattern of the opiate receptar binding is independent of both total protein content and protein concentration. The level of ³H-naloxone binding in brain regions, pylorus and ileum was divided into 3 groups according to the developmental pattern of ³H-naloxone binding. The cortex and midbrain belong to high binding group. The hypothalamus, striatum, and medulla oblongata belong to moderate binding group. ³H-Naloxone binding was low in the cerebellum, pylorus and ileum. Distinct differences between male and female rats were observable in the brain regions. The pattern of opiate receptor binding in the pylorus and ileum is more like that in the cerebellum than in any other brain regions.
외부 물질의 주입에 의해 발생한 이물 육아종의 임상 및 병리조직학적 고찰
심우행 ( Woo Haing Shim ),좌승욱 ( Seung Wook Jwa ),송마가렛 ( Mar Ga Ret Song ),김훈수 ( Hoon Soo Kim ),고현창 ( Hyun Chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon Bum Kim ) 대한피부과학회 2011 大韓皮膚科學會誌 Vol.49 No.9
Background: Various foreign materials injected into the skin can cause foreign body granuloma, which can cause severe disfigurement. Objective: To describe the clinicopathological characteristics of injection-induced foreign body granuloma. Methods: We did a retrospective study of 27 cases of injection-induced foreign body granuloma. Factors investigated included sex, age, injected material, purpose of injection, operator who gave the injection, number of injections, onset time of the granuloma after the injection, affected parts of the body, cutaneous manifestations, associated symptoms, histopathologic findings, treatment modalities and clinical course. Results: The male-female ratio was 2 to 25. Twenty five patients received injection for cosmetic improvement and 2 patients for treatment of musculoskeletal disease. Twenty patients were treated by unlicensed practitioners. The injected materials were unknown in 14 cases, whereas silicone (n=5) was most common among known injected materials. On average, foreign body granuloma occurred 131.3±136.3 months after injection. The face was the most frequently affected site and usually presented as skin-colored or erythematous plaques. The histopathologic exam revealed variable infiltration of inflammatory cells, including lymphocytes, histiocytes, multinucleated giant cells, plasma cells, neutrophils, and eosinophils. A swiss cheese appearance was observed in 19 cases. Complete response was achieved in four patients: those who had been treated with surgical excision (n=2) and those treated with systemic corticosteroids with antibiotics (n=2). Conclusion: Foreign body granuloma can arise from injection of various foreign materials. Dermatologists should be aware of the clinical manifestations of injection-related foreign body granuloma to make an appropriate diagnosis and to provide proper treatment. Moreover, there should be great social concern about injection-related foreign body granuloma, because many cases are caused by unlicenced practitioners. (Korean J Dermatol 2011;49(9):801~808)
특징적인 Dermoscopy 소견을 보이며 국소 Tacalcitol 치료에 의해 호전된 천공성 광택태선
심우행 ( Woo Haing Shim ),좌승욱 ( Seung Wook Jwa ),송마가렛 ( Mar Ga Ret Song ),김훈수 ( Hoon Soo Kim ),고현창 ( Hyun Chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon Bum Kim ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.12
Perforating lichen nitidus is an unusual variant of lichen nitidus. It is clinically characterized by umbilicated papules and histopathologically characterized by transepidermal elimination of inflammatory debris from granulomatous infiltrates. Most cases of perforating lichen nitidus are treated with topical corticosteroids, but long-term use of topical corticosteroids could provoke several side effects. Herein, we report a case of perforating lichen nitidus treated effectively and safely with topical tacalcitol ointment. We performed a dermoscopic examination for the perforating lichen nitidus lesion and found the characteristic frogspawn dermoscopic feature. (Korean J Dermatol 2011;49(12):1083~1086)
Yamaoka, Yasuyo,Achard, Dorine,Jang, Sunghoon,Legé,ret, Bertrand,Kamisuki, Shogo,Ko, Donghwi,Schulz‐,Raffelt, Miriam,Kim, Yeongho,Song, Won‐,Yong,Nishida, Ikuo,Li‐,Beisson, Yon BLACKWELL 2016 PLANT BIOTECHNOLOGY JOURNAL Vol.14 No.11
<P><B>Summary</B></P><P>Despite a strong interest in microalgal oil production, our understanding of the biosynthetic pathways that produce algal lipids and the genes involved in the biosynthetic processes remains incomplete. Here, we report that <I>Chlamydomonas reinhardtii Cre09.g398289</I> encodes a plastid‐targeted 2‐lysophosphatidic acid acyltransferase (CrLPAAT1) that acylates the <I>sn</I>‐2 position of a 2‐lysophosphatidic acid to form phosphatidic acid, the first common precursor of membrane and storage lipids. <I>In vitro</I> enzyme assays showed that CrLPAAT1 prefers 16:0‐CoA to 18:1‐CoA as an acyl donor. Fluorescent protein‐tagged CrLPAAT1 was localized to the plastid membrane in <I>C. reinhardtii</I> cells. Furthermore, expression of CrLPAAT1 in plastids led to a > 20% increase in oil content under nitrogen‐deficient conditions. Taken together, these results demonstrate that CrLPAAT1 is an authentic plastid‐targeted LPAAT in <I>C. reinhardtii</I>, and that it may be used as a molecular tool to genetically increase oil content in microalgae.</P>
손발톱주위 사마귀에 대한 Bleomycin 병변내 주사요법 후 발생한 손발톱위축증 5예
김태욱 ( Tae Wook Kim ),좌승욱 ( Seung Wook Jwa ),송마가렛 ( Mar Ga Ret Song ),김훈수 ( Hoon Soo Kim ),고현창 ( Hyun Chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon Bum Kim ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.3
Onychatrophy is the processes in which the nail has initially formed satisfactorily and then shows total or partial regression. The causes of onychatrophy with pterygium include lichen planus, acrosclerosis, Stevens-Johnson syndrome, and cicatrical pemphigoid, and those without pterygium include severe paronychia, Stevens-Johnson syndrome, epidermolysis bullosa, and drugs. Bleomycin is an antitumor, antibacterial, and antiviral agent used in many dermatologic diseases such as warts, vascular anomalies, hemangioma, and cutaneous malignancies. Cutaneous adverse effects of bleomycin strongly depend on the route of administration and dosage. Bleomycin intralesional injection for periungual warts could result in permanent Raynaud phenomenon, nail dystrophy, and nail loss. We report five cases of onychatrophy following bleomycin intralesional injections for periungual warts. We remind that if bleomycin intralesional injection near the nail matrix is inevitable in recalcitrant periungual warts, the performer must manipulate precisely to avoid adverse effects. (Korean J Dermatol 2012;50(3):262~265)
유향석 ( Hyang Suk You ),문제호 ( Je Ho Mun ),좌승욱 ( Seung Wook Jwa ),송마가렛 ( Mar Ga Ret Song ),김훈수 ( Hoon Soo Kim ),고현창 ( Hyun Chang Ko ),김문범 ( Moon Bum Kim ),김병수 ( Byung Soo Kim ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.7
Various modalities have been used for the treatment of psoriasis, including phototherapy. The choice of psoriasis treatment is based on the characteristics of the lesions, locations and amount of involved body surface area. Narrowband ultraviolet (UV) B therapy is a widely used and highly efficient method for psoriasis. But, large areas of unaffected skin may be irradiated along with the psoriatic lesions during phototherapy. The 308-nm excimer laser is a further development of narrowband UVB and was reported to be an effective and safe treatment for localized psoriasis. We experienced an excellent effect without significant adverse reactions of 308-nm excimer laser in a 9-year-old patient with palmoplantar psoriasis who was recalcitrant to oral cyclosporine and topical calcipotriol/ betamethasone treatment. (Korean J Dermatol 2013;51(7):527∼530)
스파르가눔증 스파르가눔증 진단에서 초음파 검사의 유용성
진현주 ( Hyun Ju Jin ),문제호 ( Je Ho Mun ),좌승욱 ( Seung Wook Jwa ),송마가렛 ( Mar Ga Ret Song ),고현창 ( Hyun Chang Ko ),김병수 ( Byung Soo Kim ),김문범 ( Moon Bum Kim ),김훈수 ( Hoon Soo Kim ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.12
Sparganosis is a kind of parasitic skin disease caused by sparganum, the plerocercoid larvae of the taper worm of the genus Spirometra. Sparganosis usually manifests as migrating or fixed subcutaneous nodules; therefore, it should be differentiated from lipoma, cysts, and cutaneous malignancies. Although the final diagnosis of sparganosis in humans depends on the identification of the worm in an infected tissue, suspicion for the presence of the parasite and careful history taking are important before making the diagnosis. However, it might be difficult for a clinician to suspect the existence of sparganosis because the incidence of this disease is extremely low. Therefore, an effective method for differentiating sparganosis from other skin disorders is needed. We suggest that ultrasonography could be an answer to this problem, on the basis of our experience of a case of cutaneous sparganosis in a 65-yearold woman showing very characteristic ultrasonographic findings. (Korean J Dermatol 2014;52(12):907∼910)