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      • KCI등재후보

        The Severity of Cleft Lip and Palate and Postsurgical Outcome in Non-syndromic Complete Unilateral Cleft Lip and Palate: A Pilot Study Based on Surgeon’s Perception

        Pollyana Marques de Moura(Pollyana Marques de Moura),James Seaward(Seaward James),Alex Kane(Alex Kane),Yong Jong Park(Yong Jong Park) 대한구순구개열학회 2023 대한구순구개열학회지 Vol.26 No.1

        Objective: The aim of this study was to assess the pre-operative and post-operative aesthetic outcome of patients following primary lip repair to investigate the association of the severity of the cleft deformity after NAM therapy and final surgical outcome. Materials and Methods: To assess the correlation between severity of the cleft and the primary surgery outcome, four pediatric craniofacial surgeons from the affiliated teaching hospital were asked to independently rate 156 randomized sets of photographs from 39 case of non-syndromic patients with complete unilateral cleft lip and palate who received NAM treatment.by mean of visual analogue scale. The photographs were acquired in four different time points: (T1) Pre NAM therapy, (T2) Post NAM therapy, (T3) Immediate post-operative, (T4) Late post-operative. Results: The mean of VAS score for lip and nose improved significantly after NAM therapy. There was significant correlation between NAM treatment (T2) outcome and immediate post-operative outcome (T3) for nose. There was no significant correlation between NAM treatment outcome (T2) and immediate postoperative outcome (T3) or late postoperative outcome for lip. Conclusion: Cleft deformity improved significantly after NAM therapy and this improvement led to better nasal esthetics immediate post operatively.

      • KCI등재
      • SCIESCOPUSKCI등재

        PERFORMANCE OF SMALL SCALE LIVESTOCK/CROP DEMONSTRATION-CUM-TRAINING FARMS IN SRI LANKA

        de Jong, R.,Kuruppu, L.G.,Jayawardena, Q.W.,Ibrahim, M.N.M. Asian Australasian Association of Animal Productio 1994 Animal Bioscience Vol.7 No.4

        Three livestock/crop demonstration-cum-training farms have been established on plots of half, one and two acres, typical of the "Kandyan Forest Garden System" Vegetables, bananas, pepper, coffee, coconut and fruit trees are widely spaced, for intercropping with grass, and have been surrounded with live fences that also provide fodder for livestock to increase the family income. Each unit is operated by a selected employee and his family under a monthly incentive scheme based upon the gross margin. On these farms the technical parameters in dairying are better than elsewhere in the Mid-Country. Economic performance over 1985-1992 showed that dairying contributed most to the total gross margin of the half, one and two acre units, i.e. 31, 63 and 69%, respectively. Next came crops (29%, 37% and 19%), poultry (22%, 0% and 9%), and goats (18%, 0% and 3%). In the three farms the cash income per Sri Lankan Rupee spent was 1.5, 4.6 and 2.1, respectively. The overall ratio was 3.2 for dairying, 1.1 for poultry, 4.5 for goats and 9.9 for crops. Actual family labour in the three farms was 548, 548 and 639 days, compared to the 270, 330 and 440 days anticipated in the initial feasibility study. The average incentive payments, which were 20% (half acre), 61% (one acre) and 133% (two acres) of the parastatal salary of the employee, were only insufficient for the extra labour applied in the half acre unit. Dairying and goats proved to be attractive cash earners with a domestic fuel were important benefits. Poultry did little to improve farm income.

      • KCI등재

        Male Attitudes towards Infertility: Results from a Global Questionnaire

        De Jonge Christopher J.,Gellatly Steven A.,Vazquez-Levin Mónica H.,Barratt Christopher L.R.,Rautakallio-Hokkanen Satu 대한남성과학회 2023 The World Journal of Men's Health Vol.41 No.1

        Purpose: In general, men are less likely to seek health care than women. Infertility is a global disease that afflicts approxi-mately 15% of reproductive age couples and the male contributes to 40% of the diagnosable cause. Remarkably, no large or multi-national population data exist regarding men’s perceptions about their infertility. The purpose of this study was to advance our knowledge about the infertile male’s social experience regarding: (1) how they feel about their infertility, (2) what motivated them to seek health care, (3) how likely are they to talk with others about their infertility, (4) their awareness of male infertility support groups, and (5) what their primary source for information is regarding male infertility? Based on the results from this study, these simple questions now have clearer definition. Materials and Methods: An Institutional Review Board-approved, male-directed, anonymous questionnaire translated into 20 languages was made globally available through the Fertility Europe website (https://fertilityeurope.eu). Males (n=1,171) age 20–49 years were invited to complete the online survey after informed consent. Results: Most respondents were European (86%). Of European men, <15.8% were self-motivated to seek medical help. Fur-ther, their physician was not the primary source of information regarding their infertility. While most men (59%) viewed their infertility positively, a large majority were not very likely (73%) to talk about it. Most respondents indicated a lack of aware-ness or absence of male infertility support groups. Conclusions: These are the first multi-national population data revealing men’s feelings about their infertility, what motivates them to seek help and their awareness of resources for peer support and information. These findings also serve to highlight significant gaps that exist in the provision of male reproductive health care and in supportive resources for men suffering from infertility. We offer recommendations on how to address the problem(s).

      • Round robin study to evaluate the reconstructed human epidermis (RhE) model as an in vitro skin irritation test for detection of irritant activity in medical device extracts

        De Jong, Wim H.,Hoffmann, Sebastian,Lee, Michelle,Kandá,rová,, Helena,Pellevoisin, Christian,Haishima, Yuji,Rollins, Beau,Zdawczyk, Austin,Willoughby, Jamin,Bachelor, Michael,Schatz, Timot Elsevier 2018 Toxicology in vitro Vol.50 No.-

        <P><B>Highlights</B></P> <P> <UL> <LI> Alternative in vitro testing of medical device extracts for irritation is possible. </LI> <LI> Reconstructed human epidermis (RhE) model detects presence of irritant in extracts. </LI> <LI> High predictivity RhE model for presence of strong irritants in material extracts. </LI> <LI> Predictivity in saline or sesame oil extract depends on hydrophilicity of irritant. </LI> <LI> Four positive polymer test materials containing a known irritant were evaluated. </LI> </UL> </P>

      • SCIESCOPUSKCI등재
      • KCI등재

        공개키 공격에 안전한 비대칭 워터마킹

        이덕(De Li),김종원(Jong-Weon Kim),최종욱(Jong-Uk Choi) 한국컴퓨터정보학회 2008 韓國컴퓨터情報學會論文誌 Vol.13 No.7

        본 논문에서는 공개키 공격에 안전한 비대칭 워터마킹 시스템을 구성하기 위하여 효과적인 공개 키 및 개인 키 생성 알고리즘을 제안한다. 공개 키와 개인 키의 생성은 특수행렬을 이용한 선형변환 방식에 기초하였으며 높은 상관도 검출이 가능하도록 구성되었다 또 공개 키 공격에 대한검증과 검출을 위한 공개 키를 추가로 생성하여 분배하는 방안을 제안하여 특정된 환경에서 공개 키 공격에 효과적으로 대응하도록 하였다. 실험결과 워터마크가 삼입된 영상에서 공개 키 및 개인 키를 이용하여 효과적으로 높은 상관도 검출을 할 수 있었으며 공개 키 공격을 받은 영상에서 추가로 발급된 검증용 공개 키를 이용하여 효과적으로 상관도 검출을 할 수 있음을 확인하였다. In this paper, we proposed an algorithm for an effective public key and private key generation to implement a secure asymmetric watermarking system against the public key attack. The public key and private key generation is based on the linear transformation using a special matrix and the keys are designed to be able to have high correlation value. We also proposed a counter plan of public key attack. This method uses a multiple public key generation and distribution. As the results, the correlation value between the public key and the private key is high in the watermarked image. After the public key attack. this can detect the correlation by using other public key.

      • KCI등재

        Apparent partial loss 40Ar/39Ar age spectra of hornblende from the Palaeoproterozoic Lapland-Kola orogen (arctic European Russia): insights from numerical modelling and multi-method in-situ micro-sampling geochronology

        Koen de Jong 한국지질과학협의회 2009 Geosciences Journal Vol.13 No.3

        40Ar/39Ar age spectra with progressively increasing step ages are well known for metamorphic hornblende and have been classically interpreted by partial loss of radiogenic argon by diffusion processes during younger thermo-tectonic reworking. Application of a number of numerical modelling tools based on diffusion theory and that assume thermally activated loss of radiogenic 40Ar by solid-state volume diffusion suggests that staircaseshaped age spectra of Neoarchaean tschermakitic hornblende from the Lapland-Kola Orogen are due to argon losses of 40–50% during reheating to 450 ± 25 oC in Palaeoproterozoic time. However, in hornblende samples that yielded staircase-type age spectra, biotite occurs in the matrix, as well as intimately and abundantly intergrown with the amphibole along grain boundaries, cleavages, fractures and other defects. Drilling of 1.5 mm diameter discs from carefully selected hornblende grains in petrographic thin sections permitted to minimise the effects of contaminant biotite inclusions and/or compositional zoning of the amphibole. 40Ar/39Ar laser probe step-heating of drilled biotite-free hornblende discs yielded flat age spectra, suggesting absence of thermally activated radiogenic 40Ar loss. This would imply unrealistically contrasting temperature histories for neighbouring grains. Apparent-loss age spectra, thus, result from differential gas release of hornblende and an included, earlier degassing minor contamination of much younger biotite, which had apparently not been completely eliminated from the amphibole separate, despite careful handpicking. This is confirmed by the Ca/K ratio spectra − a proxy for 37ArCa/39ArK − of hornblende that are flat for drilled biotite-free hornblende grains, but initially low for hornblende separates. A drilled disc and a separate of hornblende from a biotite-free amphibolite did not yield apparent loss spectra, but flat age and Ca/K ratio spectra, confirming the interpretation of the role of biotite. 40Ar/39Ar age spectra with progressively increasing step ages are well known for metamorphic hornblende and have been classically interpreted by partial loss of radiogenic argon by diffusion processes during younger thermo-tectonic reworking. Application of a number of numerical modelling tools based on diffusion theory and that assume thermally activated loss of radiogenic 40Ar by solid-state volume diffusion suggests that staircaseshaped age spectra of Neoarchaean tschermakitic hornblende from the Lapland-Kola Orogen are due to argon losses of 40–50% during reheating to 450 ± 25 oC in Palaeoproterozoic time. However, in hornblende samples that yielded staircase-type age spectra, biotite occurs in the matrix, as well as intimately and abundantly intergrown with the amphibole along grain boundaries, cleavages, fractures and other defects. Drilling of 1.5 mm diameter discs from carefully selected hornblende grains in petrographic thin sections permitted to minimise the effects of contaminant biotite inclusions and/or compositional zoning of the amphibole. 40Ar/39Ar laser probe step-heating of drilled biotite-free hornblende discs yielded flat age spectra, suggesting absence of thermally activated radiogenic 40Ar loss. This would imply unrealistically contrasting temperature histories for neighbouring grains. Apparent-loss age spectra, thus, result from differential gas release of hornblende and an included, earlier degassing minor contamination of much younger biotite, which had apparently not been completely eliminated from the amphibole separate, despite careful handpicking. This is confirmed by the Ca/K ratio spectra − a proxy for 37ArCa/39ArK − of hornblende that are flat for drilled biotite-free hornblende grains, but initially low for hornblende separates. A drilled disc and a separate of hornblende from a biotite-free amphibolite did not yield apparent loss spectra, but flat age and Ca/K ratio spectra, confirming the interpretation of the role of biotite.

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