Experimental and Theoretical Investigation on Flexural Behavior of Corroded Steel Beams Strengthened by CFRP Plate

Zong-Xing Zhang,Shan-Hua Xu,Lin Mu,Sheng-Yuan Peng 대한토목학회 2020 KSCE JOURNAL OF CIVIL ENGINEERING Vol.24 No.7

To investigate the flexural behavior of corroded steel beams strengthened by carbon fiber reinforced polymer (CFRP) plate, flexural test of five steel beams were carried out. The effects of corrosion and prestressing force levels on the flexural capacity, failure modes and interfacial stress were investigated. Meanwhile, considering the corrosion surface the calculation method of flexural capacity of corroded beams strengthened by CFRP plate was also established. The results showed that failure modes of corroded beams were the fracture of the CFRP plate after the shear failure of interface on the mid-span and fracture location of CFRP plate was mostly at the loading point. The rough surface of the corroded steel can enhance the efficiency of stress transfer at the interface, thereby improving the effective bond length of the interface. The shear stress was mainly concentrated on the CFRP plate end, and peak value appeared at the loading point. Compared the reference beam, the ultimate flexural capacity of the corroded beam strengthened by CFRP plate with 15% prestress level increased at a ratio of 21%, and utilization ratio of the CFRP plates was up to 71.59%.

White Matter Microstructural Similarity and Diversity of Functional Constipation and Constipation-predominant Irritable Bowel Syndrome

( Jiaofen Nan ),( Liangliang Zhang ),( Qiqiang Chen ),( Nannan Zong ),( Peiyong Zhang ),( Xing Ji ),( Shaohui Ma ),( Yuchen Zhang ),( Wei Huang ),( Zhongzhou Du ),( Yongquan Xia ),( Ming Zhang ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2018 Journal of Neurogastroenterology and Motility (JNM Vol.24 No.1

Background/Aims The Rome III criteria separated chronic constipation into functional constipation (FC) and constipation-predominant irritable bowel syndrome (IBS-C), but some researchers questioned the partitioning and treated both as distinct parts of a continuum. The study aims to explore the similarity and diversity of brain white matter between FC and IBS-C. Methods The voxel-wise analysis of the diffusion parameters was used to quantify the white matter changes of female brains in 18 FC patients and 20 IBS-C patients compared with a comparison group with 19 healthy controls by tract-based spatial statistics. The correlations between diffusive parameters and clinical symptoms were evaluated using a Pearson’s correlation. Results In comparison to healthy controls, FC patients showed a decrease of fractional anisotropy (FA) and an increase of radial diffusivity (RD) in multiple major fibers encompassing the corpus callosum (CC, P = 0.001 at peak), external capsule (P = 0.002 at peak), corona radiata (CR, P = 0.001 at peak), and superior longitudinal fasciculus (SLF, P = 0.002 at peak). In contrast, IBS-C patients showed FA and RD aberrations in the CC (P = 0.048 at peak). Moreover, the direct comparison between FC and IBS-C showed only RD differences in the CR and SLF. In addition, FA and RD in the CC were significantly associated with abdominal pain for all patients, whereas FA in CR (P = 0.016) and SLF (P = 0.040) were significantly associated with the length of time per attempt and incomplete evacuation separately for FC patients. Conclusion These results may improve our understanding of the pathophysiological mechanisms underlying different types of constipation. (J Neurogastroenterol Motil 2018;24:107-118)

On Generating Fuzzy Systems based on Pareto Multi-objective Cooperative Coevolutionary Algorithm

Zong-Yi Xing,Yong Zhang,Yuan-Long Hou,Li-Min Jia 대한전기학회 2007 International Journal of Control, Automation, and Vol.5 No.4

An approach to construct multiple interpretable and precise fuzzy systems based on the Pareto Multi-objective Cooperative Coevolutionary Algorithm (PMOCCA) is proposed in this paper. First, a modified fuzzy clustering algorithm is used to construct antecedents of fuzzy system, and consequents are identified separately to reduce computational burden. Then, the PMOCCA and the interpretability-driven simplification techniques are executed to optimize the initial fuzzy system with three objectives: the precision performance, the number of fuzzy rules and the number of fuzzy sets; thus both the precision and the interpretability of the fuzzy systems are improved. In order to select the best individuals from each species, we generalize the NSGA-Ⅱ algorithm from one species to multi-species, and propose a new non-dominated sorting technique and collaboration mechanism for cooperative coevolutionary algorithm. Finally, the proposed approach is applied to two benchmark problems, and the results show its validity.

Evaluation of Several Screening Approaches for Detection of Cervical Lesions in Rural Shandong, China

Zong, Li-Ju,Zhang, You-Zhong,Yang, Xing-sheng,Jiang, Jie,Cui, Bao-Xia,Qiao, Yun-Bo,Li, Li,Jiang, Kan,Zhang, Wen-Jing,Kong, Bei-Hua,Shen, Keng Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.5

Purpose: The study was designed to: (1) investigate the prevalence of high-risk human papillomavirus (HR-HPV) infection and cervical neoplasia; and (2) evaluate clinical performance of visual inspection with acetic acid/ Lugol's iodine (VIA /VILI), Pap smear, high-risk human papillomavirus (HR-HPV) DNA test for detecting cervical intraepithelial neoplasia grade 2 or worse (CIN2+) and (3) explore appropriate screening approach in rural areas of Shandong Province. Materials and Methods: A total of 3,763 eligible women from Yiyuan County in Yimeng mountainous areas of rural Shandong, China, were enrolled and underwent Pap smear, HR-HPV DNA testing by Hybrid Capture 2 (HC2), and VIA /VILI tests. Women positive in any test were referred to colposcopy and biopsy as indicated. Results: The prevalence of HR-HPV infection among all enrolled women was 11.1% and that in healthy women was 9.9%. In total 33 cases of CIN1, 16 cases of CIN2, 6 cases of CIN3 but none of cervical cancer were detected and the crude prevalence of CIN2+ was 0.58%. For detecting CIN2+, the sensitivity of HR-HPV DNA testing, VIA/VILI, Pap smear was 90.9%, 77.3%, 81.8%, respectively. Pap smear had the best specificity of 98.2%, followed by HR-HPV DNA testing with specificity of 89.4%, VIA/VILI had the lowest specificity of 81.2%. Colposcopy referral rate of HR-HPV DNA testing, VIA/VILI, Pap smear was 11.1%, 18.5%, 2.3%, respectively. Conclusions: Our results suggest that HR-HPV DNA testing alone might be appropriate for primary cervical cancer screening in rural low-resource areas of Shandong Province, China.

A Hierarchical Genetic Algorithm based RBF Neural Network Approach for Modelling of Electrohydraulic System

Xing Zong-yi,Zhang Yuan,Qin Yong,Jia Li-min,Wu Ying-ying 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8

The paper presents an approach to model the electrohydraulic system of a certain mine-sweeping weapon using the Radial Basis Function (RBF) neural networks. In order to obtain accurate and simple RBF neural networks efficiently, a hierarchical genetic algorithm (HGA) is used to train the neural networks, in which the number of hidden units and the parameters of centers are optimized by the HGA simultaneously. The spread factors and the weights of the neural networks are calculated by the linear algebra methods for relieving computational burden. The proposed algorithm is applied to the modelling of the electrohydraulic system, and the results clearly indicate that the obtained RBF neural network can model the hydraulic system satisfactorily. The comparison results also show that the proposed algorithm performs better than the traditional methods.

PU.1 Is Identified as a Novel Metastasis Suppressor in Hepatocellular Carcinoma Regulating the miR-615-5p/IGF2 Axis

Song, Li-Jie,Zhang, Wei-Jie,Chang, Zhi-Wei,Pan, Yan-Feng,Zong, Hong,Fan, Qing-Xia,Wang, Liu-Xing Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9

Invasion and metastasis is the major cause of tumor recurrence, difficulty for cure and low survival rate. Excavating key transcription factors, which can regulate tumor invasion and metastasis, are crucial to the development of therapeutic strategies for cancers. PU.1 is a master hematopoietic transcription factor and a vital regulator in life. Here, we report that, compared to adjacent non-cancerous tissues, expression of PU.1 mRNA in metastatic hepatocellular carcinoma (HCC), but not primary HCC, was significantly down-regulated. In addition, levels of PU.1 mRNA in metastatic hepatoma cell lines MHCC97L and MHCC97H were much lower than in non-metastatic Hep3B cells. Transwell invasion assays after PU.1 siRNA transfection showed that the invasion of hepatoma cell lines was increased markedly by PU.1 knockdown. Oppositely, overexpression of PU.1 suppressed the invasion of these cells. However, knockdown and overexpression of PU.1 did not influence proliferation. Finally, we tried to explore the potential mechanism of PU.1 suppressing hepatoma cell invasion. ChIP-qPCR analysis showed that PU.1 exhibited a high binding capacity with miR-615-5p promoter sequence. Overexpression of PU.1 caused a dramatic increase of pri-, pre- and mature miR-615-5p, as well as a marked decrease of miR-615-5p target gene IGF2. These data indicate that PU.1 inhibits invasion of human HCC through promoting miR-615-5p and suppressing IGF2. These findings improve our understanding of PU.1 regulatory roles and provided a potential target for metastatic HCC diagnosis and therapy.

Anomalous Ferromagnetism and Electron Microscopy Characterization of High-Quality Neodymium Oxychlorides Nanocrystals

Xinliang Zheng,Juan Feng,Jiarui Zhang,Hongna Xing,Jiming Zheng,Mingzi Wang,Yan Zong,Jintao Bai,Xinghua Li 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2016 NANO Vol.11 No.3

High-quality neodymium oxychlorides nanocrystals with cubic shape were synthesized by a nonhydrolytic thermolysis route. The morphology and crystal structure of the neodymium oxychlorides nanocubes were characterized by transmission electron microscopy at the nanoscale. Transmission electron microscope (TEM) image shows that the neodymium oxychlorides nanocrystals are nearly monodispersed with cube-like shape. X-ray diffraction (XRD) and selected area electron diffraction (SAED) patterns of numerous neodymium oxychlorides nanocubes suggest a pure crystal phase with tetragonal PbFCl matlockite structure. HRTEM image of individual neodymium oxychlorides nanocubes indicate that each nanocubes have a singlecrystalline nature with high quality. Unlike the anti-ferromagnetism of the bulk, the neodymium oxychlorides nanocubes show clearly anomalous ferromagnetic characteristic at room temperature. This finding provides a new platform for the exploration of diluted magnetic semiconductors, rare earth-based nanomaterials and so on.

Degradation Model and Evaluation Criteria for the Seismic Behavior of Corrosion H-section Steel Column

Guang-chong Qin,Tao Lan,Qing Qin,Shan-hua Xu,Zong-xing Zhang 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.8

The cross section would be reduced and the material properties of the steel structure would be deteriorated under the corrosion environment, which will have different effects on the earthquake resistant behavior. This paper takes corroded H-steel column as the research object. Firstly, the influence on the failure mode, bearing capacity, hysteretic properties, ductility and hysteretic energy is analyzed from specific factors which consist of different width-to-thickness on flange, different height-to-thickness on web and different axial compression ratios by FEA. The results show that, the area of the hysteresis loop diminishes gradually, the bearing capacity decrease clearly, the accumulative energy dissipation and ductility coefficient decreased continuously, and the degradation laws of buckling load, peak load, hysteretic energy and ductility coefficient of corroded H-steel columns are thereby established. When the thickness of flange decreased by 30%, the peak load decreased by 32% and hysteretic energy decreased by 77%. However, the peak load decreased by 14% and hysteretic energy decreased by 40% when the thickness of web decreased by 30%. When the axial compression ratio is 0.6, and the mass loss ratio of corroded H-steel columns reached 22%, the peak load and hysteretic energy decreased by 28% and 51% respectively. Secondly, the hysteretic model of load-displacement of corroded H-steel members under cyclic loading is proposed based on the simulation results and the degradation model of characteristic point of skeleton line was given. Finally, the evaluation criteria are proposed based on the seismic performance objectives, and the classification of failure types as well as the overall performance evaluation of corroded steel members are carried out.

QTL mapping and identification of candidate genes for cold tolerance at the germination stage in wild rice

Pan Ying-Hua,Nong Bao-Xuan,Chen Lei,Yang Xing-Hai,Xia Xiu-Zhong,Zhang Zong-Qiong,Qing Dong-Jin,Gao Ju,Huang Cheng-Cui,Li Dan-Ting,Deng Guo-Fu 한국유전학회 2023 Genes & Genomics Vol.45 No.7

Background Cold damage stress significantly affects rice growth (germination and seedling) and causes serious losses in yield in temperate and high-altitude areas around the globe. Objective This study aimed to explore the cold tolerance (CT) locus of rice and create new cold-tolerant germplasm. We constructed a chromosome segment substitution line (CSSL) with strong CT and fine mapped quantitative trait loci (QTLs) associated with CT by performing the whole-genome resequencing of CSSL with phenotypes under cold treatment. Methods A chromosome CSSL, including 271 lines from a cross between the cold-tolerant wild rice Y11 (Oryza rufipogon Griff.) and the cold-sensitive rice variety GH998, was developed to map QTLs conferring CT at the germination stage. The whole-genome resequencing was performed on CSSL for mapping QTLs of associated with CT at the germination stage. Results A high-density linkage map of the CSSLs was developed using the whole-genome resequencing of 1484 bins. The QTL analysis using 615,466 single-nucleotide polymorphisms (SNPs) led to the identification of 2 QTLs related to germination rate at low-temperature on chromosome 8 (qCTG-8) and chromosome 11 (qCTG-11). The qCTG-8 and qCTG-11 explained 14.55% and 14.31% of the total phenotypic variation, respectively. We narrowed down qCTG-8 and qCTG-11 to 195.5 and 78.83-kb regions, respectively. The expression patterns of important candidate genes in different tissues, and of RNA-sequencing (RNA-seq) in CSSLs, were identified based on gene sequences in qCTG-8 and qCTG-11 cold-induced expression analysis. LOC_Os08g01120 and LOC_Os08g01390 were identified as candidate genes in qCTG-8, and LOC_Os11g32880 was identified as a candidate gene in qCTG-11. Conclusions This study demonstrated a general method that could be used to identify useful loci and genes in wild rice and aid in the future cloning of candidate genes of qCTG-8 and qCTG-11. The CSSLs with strong CT were supported for breeding cold-tolerant rice varieties.

A multipath peroxymonosulfate activation process over supported by magnetic CuO-Fe3O4 nanoparticles for efficient degradation of 4-chlorophenol

Wei Peng,Jie Liu,Wei Peng,Chenxu Li,Fuxing Zong,Wensi Xu,Xing Zhang 한국화학공학회 2018 Korean Journal of Chemical Engineering Vol.35 No.8

Heterogeneous catalysts with low cost, environmentally friendly, highly effective and ready separation from aqueous solution are highly desirable. Magnetic CuO-Fe3O4 nanoparticles, a type of non-toxic bimetallic transition metal oxide, is a promising heterogeneous catalyst for activation of peroxymonosulfate (PMS) to generate reactive oxygen species (ROS) that has not been previously investigated. In this study, the activation of PMS by CuO-Fe3O4 nanoparticles was evaluated using the degradation of 4-chlorophenol as a model reaction. Several critical factors such as pH, catalyst dosage and PMS concentration were investigated. CuO-Fe3O4/PMS system demonstrated a wide effective pH range to degrade 4-chlorophenol, namely 5.5 to 9.5. With the increase of the catalyst dosage, the degradation efficiency of 4-chlorophenol appeared to increase first and then decrease, that the inflection point was 0.5 g/L. Elevated PMS concentration obviously improved the decomposition of 4-chlorophenol; however, the plateau was reached when the PMS concentration was 8mM. Further increase in PMS concentration would not significantly improve the removal efficiency. Through examining the effects of scavengers and electron spin resonance (ESR) analyses, CuO-Fe3O4 nanoparticles were proven to activate PMS through a non-radical and radical pathway to generate singlet oxygen, sulfate radicals and hydroxyl radicals. Based on results, CuO-Fe3O4 nanoparticles were effective, environmentally friendly and low cost catalysts for efficient activation of PMS. These features make CuO-Fe3O4 nanoparticles a readily available heterogeneous catalyst to activate PMS for refractory organic pollutants degradation in advanced oxidation processes (AOPs).