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Efficient Query Processing Platform for Uncertain Big Data
Zhenhua Huang,Jiawen Zhang,Qiang Fang 보안공학연구지원센터 2015 International Journal of Database Theory and Appli Vol.8 No.5
Query processing technology has recently received a lot of attention in the business intelligence and information service communities. However, the existing approaches can not efficiently optimize the query performance in the uncertain big data environment. In this paper, we propose QPPUBG, a novel and efficient query processing platform for uncertain big data. QPPUBG mainly includes four modules: (i) query equivalence reconstructing for uncertain big data; (ii) multiple query optimization over probability relation components; (iii) query execution plan constructing over probability relation components, and (iv) physical implementation solution of query for uncertain big data. Specially, QPPUBG can support the possible world instance semantics and efficiently handle arbitrary decision spaces. Moreover, QPPUBG can seamlessly integrate the above four modules into the modern parallel computation frameworks. We present the extensive experiments that demonstrate QPPUBG is both efficient and effective.
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magnetostratigraphy, 26Al-10Be, Yx02 borehole, tectonic evolution, Daxing Uplift, Beijing Sub-plain
Fubing He,Xiwei Xu,Fang Tian,Zhenhua Liu,Yueze Zhang,Lingyan Bai,Yubin Cui,Kai Wang,Wenzhi Niu,Jingbo Ni,Xiaoyong Liu,Mengmeng Cao 한국지질과학협의회 2024 Geosciences Journal Vol.28 No.2
The buried Daxing Uplift connects the Beijing Sag and Dachang Sag, which is the critical tectonic unit for understanding the structural evolution of the Beijing Sub-plain and its linkages to regional tectonics. This study combines paleomagnetic, 26Al-10Be isochron dates and sedimentary analyses from a new borehole (Yx02) in the northeastern Beijing Sub-plain to shed fresh light on regional tectonic processes and the sedimentary history since the Pliocene. The main findings are as follows: (1) the Daxing Uplift had formed three depositional episodes: alluvial-fan, lacustrine-delta, and alluvial-fan sedimentation since the Cenozoic; (2) The borehole records the Brunhes, Gauss normal chron, and the Matuyama, Gilbert reversed chron in the Daxing Uplift, the corresponding depths are 0–148.9 m, 148.9–315.0 m, 315.0–520.5 m and 520.5–650 m; (3) An important tectonic event started in ~4.3 Ma, disintegrated NE-trending basin and range terrain, reactivated the NW-trending Nankou-Sunhe fault, and formed Shunyi fault in Beijing Sub-plain. Sedimentation occurs exclusively in the Beijing Sag and the northeastern Daxing Uplift during ~4.3–1.77 Ma; (4) During ~1.77–1.07 Ma, a transition from an extension to a strike-slip occurred, and is described not only in a progressively higher increase of the overall deposition rate, but also in a decrease of the relative deposition disparity between sags and uplifts. Since then, the Beijing Sub-plain has been shaped, associated with an overall subsidence depression in the Bohai Bay Basin. This work enhances our understanding of the formation and evolution of the Beijing Sub-plain, the division of tectonic episodes, and the initiation time of the latest tectonic movement in the break-up region, North China Craton, since the Neogene.
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Zhibo Sun,Jing Jiao,Feng Liu,Yue Yang,Shanfeng Zhang,Zhenhua Fang,Zhipeng Dai,Zhibo Sun 생화학분자생물학회 2019 Experimental and molecular medicine Vol.51 No.-
The Wnt/β-catenin signaling pathway is associated with the pathogenesis of steroid-induced osteonecrosis. Our investigation studied whether aberrant CpG island hypermethylation of the FZD1 gene was present in patients with osteonecrosis of the femoral head (ONFH), which results in Wnt/β-catenin signaling inactivation and subsequent cell dysfunction. Bone marrow was collected from the proximal femurs of patients with steroid-associated ONFH (n = 21) and patients with new femoral neck fractures (n = 22), and then mesenchymal stem cells (MSCs) were isolated. We investigated cell viability, the transcription and translation levels of Wnt/β-catenin signaling-related genes, the extent of methylation at CpG islands of the FZD1 promoter, and the osteogenic and adipogenic differentiation abilities of MSCs from the control group and from the ONFH group treated with or without 5′-Aza-dC. According to the results, MSCs from the ONFH group showed a reduced proliferation ability, low transcription and translation levels of FZD1, inhibition of the Wnt/β-catenin signaling pathway, weakened osteogenesis and enhanced adipogenesis ability. Aberrant CpG island hypermethylation of FZD1 was observed in the ONFH group. Treatment with 5’-Aza-dC resulted in de novo FZD1 expression, reactivation of the Wnt/β-catenin signaling pathway and promotion of osteogenesis. Taken together, our study not only provides novel insights into the regulation of the Wnt/β-catenin signaling pathway in this disease but also reveals potential for the use of demethylating agents for the treatment of GC-associated ONFH.
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