http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Yin, Ming Zhe,Park, Seok-Woo,Kang, Tae Wook,Kim, Kyung Soo,Yoo, Hae Young,Lee, Junho,Hah, J. Hun,Sung, Myung Hun,Kim, Sung Joon The Korean Society of Pharmacology 2016 The Korean Journal of Physiology & Pharmacology Vol.20 No.1
Ion channels in carcinoma and their roles in cell proliferation are drawing attention. Intracellular $Ca^{2+}$ ($[Ca^{2+}]_i$)-dependent signaling affects the fate of cancer cells. Here we investigate the role of $Ca^{2+}$-activated $K^+$ channel (SK4) in head and neck squamous cell carcinoma cells (HNSCCs) of dif-ferent cell lines; SNU-1076, OSC-19 and HN5. Treatment with $1{\mu}M$ ionomycin induced cell death in all the three cell lines. Whole-cell patch clamp study suggested common expressions of $Ca^{2+}$-activated $Cl^-$ channels (Ano-1) and $Ca^{2+}$-activated nonselective cation channels (CAN). 1-EBIO, an activator of SK4, induced outward $K^+$ current (ISK4) in SNU-1076 and OSC-19. In HN5, ISK4 was not observed or negligible. The 1-EBIO-induced current was abolished by TRAM-34, a selective SK4 blocker. Interestingly, the ionomycin-induced cell death was effectively prevented by 1-EBIO in SNU-1076 and OSC-19, and the rescue effect was annihilated by combined TRAM-34. Con-sistent with the lower level of ISK4, the rescue by 1-EBIO was least effective in HN5. The results newly demonstrate the role of SK4 in the fate of HNSCCs under the $Ca^{2+}$ overloaded condition. Pharmacological modulation of SK4 might provide an intriguing novel tool for the anti-cancer strategy in HNSCC.
Feasibility study of equal type, experienced and compound robots based on reliability theory
Zhe YIN,Yun-fei GUO,Mao-sheng LAI 제어로봇시스템학회 2011 제어로봇시스템학회 국제학술대회 논문집 Vol.2011 No.10
Through the introduction of the concept of reliability, events encountered by the robot are divided into three cases: the first is the one that the robot to can be sure to judge and finish the event, the second is that the robot can certainly not be able to determine if the events should be done. In both cases above the robot will be able to make a positive assessment; however, there is a fuzzy event, namely: the robot can not make sure, that this is the need to issue a request to the controller to get the new instruction, and then give a specific judge.
Ming Zhe Yin,Seok-Woo Park,Tae Wook Kang,Kyung Soo Kim,Hae Young Yoo,Junho Lee,J. Hun Hah,Myung Hun Sung,Sung Joon Kim 대한생리학회-대한약리학회 2016 The Korean Journal of Physiology & Pharmacology Vol.20 No.1
Ion channels in carcinoma and their roles in cell proliferation are drawing attention. Intracellular Ca<sup>2+</sup> ([Ca<sup>2+</sup>]<sub>i</sub>)-dependent signaling affects the fate of cancer cells. Here we investigate the role of Ca<sup>2+</sup>-activated K<sup>+</sup> channel (SK4) in head and neck squamous cell carcinoma cells (HNSCCs) of dif-ferent cell lines; SNU-1076, OSC-19 and HN5. Treatment with 1 μM ionomycin induced cell death in all the three cell lines. Whole-cell patch clamp study suggested common expressions of Ca<sup>2+</sup>-activated Cl<sup>−</sup> channels (Ano-1) and Ca<sup>2+</sup>-activated nonselective cation channels (CAN). 1-EBIO, an activator of SK4, induced outward K<sup>+</sup> current (ISK4) in SNU-1076 and OSC-19. In HN5, ISK4 was not observed or negligible. The 1-EBIO-induced current was abolished by TRAM-34, a selective SK4 blocker. Interestingly, the ionomycin-induced cell death was effectively prevented by 1-EBIO in SNU-1076 and OSC-19, and the rescue effect was annihilated by combined TRAM-34. Con-sistent with the lower level of ISK4, the rescue by 1-EBIO was least effective in HN5. The results newly demonstrate the role of SK4 in the fate of HNSCCs under the Ca<sup>2+</sup> overloaded condition. Pharmacological modulation of SK4 might provide an intriguing novel tool for the anti-cancer strategy in HNSCC.
Validity Analysis of Spray Model by Comparing Simulated with Measured Spray Liquid and Vapor Phase
( Zhe Sun ),( Xue Dong ),( Peng Yin ),( Tianyun Li ),( David L. S. Hung ),( Min Xu ) 한국액체미립화학회 2017 한국액체미립화학회 학술강연회 논문집 Vol.2017 No.-
Gasoline direct injection (GDI) Engine is proved to be a key technology to save energy and reduce emissions, which improves the overall engine performance. Spray injection affect the fuel-air mixing directly and computational fluid dynamics(CFD)software is utilized to model the macroscopic shape of the spray and the vapor mass. In this paper, the liquid and vapor phase of the spray of a one-hole injector was studied both experimentally and numerically. The structure and concentration distribution of the vapor phase of the spray, vapor mass and spray penetration were measured using laser induced exciplex fluorescence (LIEF) technique in a constant volume chamber. The simulations were performed by the CONVERGE software. Both the spray penetration and Sauter Mean Diameter (SMD) employed in the simulation were calibrated with the in-chamber measurements. The comparison of vapor concentration between the simulated results and the measured results acquired from the chamber suggest that the evaporation model of the single component fuel has significant influence on the simulated results. In addition, an analysis based on the present evaporation model has been made in this study. The results show that the 2-D plane and local line distributions of vapor concentration in simulation do not best match those from the experiments. It is found to get higher vapor concentration in the simulation model, suggesting that the relationship between vapor concentration and evaporation rate should be considered and further verified.
An Eye Location based Head Posture Recognition Method and Its Application in Mouse Operation
( Zhe Chen ),( Bingbing Yang ),( Fuliang Yin ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.3
An eye location based head posture recognition method is proposed in this paper. First, face is detected using skin color method, and eyebrow and eye areas are located based on gray gradient in face. Next, pupil circles are determined using edge detection circle method. Finally, head postures are recognized based on eye location information. The proposed method has high recognition precision and is robust for facial expressions and different head postures, and can be used in mouse operation. The experimental results reveal the validity of proposed method.
Characteristic of SiC Slurry in Ultra Precision Lapping of Sapphire Substrates
Tao Yin,ZhiDa Wang,Toshiro Doi,Syuhei Kurokawa,Zhe Tan,XiaoKang Ding,Huan Lin 한국정밀공학회 2021 International Journal of Precision Engineering and Vol.22 No.6
A method is proposed in this paper to prepare a SiC slurry with SiC particles selected by an ultrasonic-assisted elutriation method to reduce substrate surface damage caused by abrasive particles during lapping. Sapphire substrate lapping experiments were carried out using the prepared SiC slurry, and the lapping performance of the slurry was analyzed. The experimental results show that the SiC particle size is a factor that directly affects the material removal rate and surface roughness Ra, of sapphire substrates. When a SiC slurry with a particle size of 630 nm was used, the material removal rate was 508 nm/h, and the surface roughness Ra was 1.9 nm; increasing the slurry concentration and the platen rotating speed can improve the material removal rate. In addition, the agglomeration of SiC particles in the slurry depends on the pH of the slurry. Efficient precision lapping of sapphire substrates can be achieved by selecting appropriately sized SiC particles and by adjusting the slurry pH to control the agglomeration and dispersion of SiC particlesto further reduce the scratches on the substrate surface during the lapping process.