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      • KCI등재

        Vibration suppression of a dual-rotorbearing coupled system by using a nonlinear energy sink

        Yang Yang,Yuanyuan Li,Shuo Zhang 대한기계학회 2021 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.35 No.6

        The aim of this paper is to gain insight into dynamic characteristics of a dualrotor system in the absence and presence of a nonlinear energy sink. Firstly, the governing equations of motion of the dual-rotor system are derived by the Lagrange’s equation. Then the dynamic characteristics of the system in the different conditions of rotational speed ratio are investigated. On this basis, a nonlinear energy sink is introduced in the LP rotor, where the effects of rotational speed ratio on the optimization of control parameters are taken into account. At last, the vibration suppression of the dual-rotor system is carried out. Moreover, the parameters analysis of the system is accomplished as well.

      • SCIESCOPUSKCI등재

        Ginsenosides Rc, as a novel SIRT6 activator, protects mice against high fat diet induced NAFLD

        Zehong Yang,Yuanyuan Yu,Nannan Sun,Limian Zhou,Dong Zhang,HaiXin Chen,Wei Miao,Weihang Gao,Canyang Zhang,Changhui Liu,Xiaoying Yang,Xiaojie Wu,Yong Gao The Korean Society of Ginseng 2023 Journal of Ginseng Research Vol.47 No.3

        Background: Hepatic lipid disorder impaired mitochondrial homeostasis and intracellular redox balance, triggering development of non-alcohol fatty liver disease (NAFLD), while effective therapeutic approach remains inadequate. Ginsenosides Rc has been reported to maintain glucose balance in adipose tissue, while its role in regulating lipid metabolism remain vacant. Thus, we investigated the function and mechanism of ginsenosides Rc in defending high fat diet (HFD)-induced NAFLD. Methods: Mice primary hepatocytes (MPHs) challenged with oleic acid & palmitic acid were used to test the effects of ginsenosides Rc on intracellular lipid metabolism. RNAseq and molecular docking study were performed to explore potential targets of ginsenosides Rc in defending lipid deposition. Wild type and liver specific sirtuin 6 (SIRT6, 50721) deficient mice on HFD for 12 weeks were subjected to different dose of ginsenosides Rc to determine the function and detailed mechanism in vivo. Results: We identified ginsenosides Rc as a novel SIRT6 activator via increasing its expression and deacetylase activity. Ginsenosides Rc defends OA&PA-induced lipid deposition in MPHs and protects mice against HFD-induced metabolic disorder in dosage dependent manner. Ginsenosides Rc (20mg/kg) injection improved glucose intolerance, insulin resistance, oxidative stress and inflammation response in HFD mice. Ginsenosides Rc treatment accelerates peroxisome proliferator activated receptor alpha (PPAR-α, 19013)-mediated fatty acid oxidation in vivo and in vitro. Hepatic specific SIRT6 deletion abolished ginsenoside Rc-derived protective effects against HFD-induced NAFLD. Conclusion: Ginsenosides Rc protects mice against HFD-induced hepatosteatosis by improving PPAR-α-mediated fatty acid oxidation and antioxidant capacity in a SIRT6 dependent manner, and providing a promising strategy for NAFLD.

      • KCI등재

        One-step synthesis of hierarchical AuNPs/Cd0.5Zn0.5S nanoarchitectures and their application as an efficient photocatalyst for hydrogen production

        Yuanyuan Liu,Cui Du,Chen Zhou,Shengyang Yang 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.72 No.-

        The hierarchical AuNPs/Cd0.5Zn0.5S hybrids are directly fabricated via a facile one-step in-situhydrothermal method. The as-prepared AuNPs/Cd0.5Zn0.5S hybrids demonstrate superior photocatalyticperformance toward hydrogen production under visible light irradiation. The hydrogen evolution rate ofthe 5 wt% AuNPs/Cd0.5Zn0.5S synthesized with in-situ hydrothermal method can be 7.1 times greater thanthat of pure Cd0.5Zn0.5S and as much as 2.5 times of 5 wt% AuNPs loaded Cd0.5Zn0.5S synthesized withphotodeposition method. Systematical investigations reveal that the enhanced photocatalyticperformance of the one-step in-situ prepared AuNPs/Zn0.5Cd0.5S can be attributed to the inherentSPR effect and favorable electron transfer properties of AuNPs, as well as the rational hierarchicalnanoarchitectures that allow AuNPs to be uniformly incorporated into Zn0.5Cd0.5S matrix. This one-stepin-situ fabrication method provides a simple and efficient route to synthesize well-definedheterocatalysts.

      • SCOPUSSCIEKCI등재

        Association between Histone Deacetylase 9 Gene Polymorphism and Stroke in Chinese Han Population

        Yang, Xitong,Xu, Hongyang,Liu, Dan,Ma, Rong,Zhang, Yuanyuan,Wang, Guangming The Korean Neurosurgical Society 2021 Journal of Korean neurosurgical society Vol.64 No.2

        Objective : To explore the correlation between the polymorphism of histone deacetylase 9 gene (rs1060499865, rs723296, rs957960) and ischemic stroke (IS) in Chinese Han population in Dali region. Methods : This study included 155 IS patients and 128 healthy physical examinees. TaqMan-polymerase chain reaction technology and multivariate logistic regression were performed. Results : In the case group, there was no polymorphism of rs1060499865 observed in the two groups; whereas on the rs723296 locus the frequencies of C allele and TC genotype were significantly higher than that in the control group, alleles C and T were associated with a 2.158-fold increase in IS risk, and genotypes TC and TT were associated with a 2.269-fold increase in IS risk. The locus rs957960 exhibited no significant difference between the two groups. Conclusion : An association between rs723296 and the risk of IS was found in the Chinese Han population in Dali region. No significant association was found between rs1060499865, rs957960 and IS in the Chinese Han population in Dali region.

      • SCOPUSSCIEKCI등재

        The Correlation between E-Selectin S128R Gene Polymorphism and Ischemic Stroke in Chinese Population : A Meta-Analysis

        Yang, Xitong,Ma, Rong,Zhang, Yuanyuan,Wang, Guangming The Korean Neurosurgical Society 2020 Journal of Korean neurosurgical society Vol.63 No.5

        To perform a systematic review of the data collected from case-control studies conducted earlier to investigate the correlation between E-selectin S128R polymorphism and ischemic stroke (IS) risk among the Chinese population. The PubMed, Web of Science, Chinese biomedical literature database (CBM), Chinese databases China National Knowledge Infrastructure (CNKI), WanfangData knowledge service platform (Wanfang Data), and information resource integration service platform (VIP) Databases were searched to retrieve case-control studies on the correlation between E-selectin gene S128R polymorphism and IS from the inception of the database till June 2019. The literature was screened, data were extracted, the risk of bias was reviewed, and the studies included were assessed independently by two reviewers. Stata ver. 12.0 software (Stata Corp LLC, College Station, TX, USA) was used to perform the meta-analysis. A total of 2907 cases from eight case-control studies involving 1478 IS patients and 1429 controls were included in this study. The R allele and RS genotype in E-selectin were found to be associated with the risk of IS as per the results of the meta-analysis (R vs. S : odds ratio [OR], 2.75; 95% confidence interval [CI], 2.15-3.51; p<0.00001; RS vs. SS : OR, 2.50; 95% CI, 1.95-3.19; p<0.00001; RR+RS vs. SS : OR, 2.85, 95% CI, 2.21-3.67; p<0.00001). The E-selectin gene S128R polymorphism is likely related to IS based on the results of a meta-analysis in the Chinese population, and the R allele and RS genotype of E-selectin may be IS risk factors.

      • A 32nm EGPU Parallel Multiprocessor Based on Co-issue and Multi-Dimensional Parallelism Architecture

        Yang Wang,Li Zhou,Tao Sun,Yanhu Chen,Jia Wang,Yuanzhi Zhang,Yuanyuan Gao 보안공학연구지원센터 2015 International Journal of Multimedia and Ubiquitous Vol.10 No.5

        In this paper, a Parallel Multiprocessor (PM) based on SIMT (Single Instruction and Multiple Threads) architecture is proposed. With co-issue architecture and multi-dimensional parallelism implemented in high-effective PM, Embedded Graphics Processing Unit (EGPU) provides great performance for various situations, such as general purpose computing, 3D scene rendering, and graphics processing. Application programs are departed into separated threads. Allocated by Thread Processing Unit (TPU), separated threads can be executed in parallel. Parallelism in different hierarchy and dimension are implemented by Multi-Dimensional Parallelism Processor (MD-PP), which has made a proper trade-off between performance and cost. Additionally, PM improves the hardware occupancy with its co-issue architecture and internal bus accessing mechanism to meet the demand of processing capability. Its unified shading architecture also helps to hide processing latency. PM can execute 4 basic operations in the best case and 2 in the worst case within each clock cycle. With 32nm process technology and 200MHz clock frequency, PM’s area is about 5104494um2, power consumption is about 101.838mW, and it can process nearly 28M vertices or fragments in average. Experimental results show that the MD-PP based PM can process data with high performance and get a balance between efficiency and hardware consumption simultaneously.

      • KCI등재

        Dynamic changes in carbohydrate metabolism and endogenous hormones during Tulipa edulis stolon development into a new bulb

        Yuanyuan Miao,Zaibiao Zhu,Qiaosheng Guo,Xiaohua Yang,Li Liu,Yuan Sun,Changlin Wang 한국식물학회 2016 Journal of Plant Biology Vol.59 No.2

        The stolon is the main asexual reproductive organ of Tulipa edulis (Miq.) Baker. It has a special morphology and can develop into a new bulb for propagation. In the current greenhouse experiment, the dynamic changes in carbohydrates and related enzymes, protein and endogenous hormones during T. edulis stolon development were investigated. The results showed that soluble sugar levels were basically declining, whereas starch and protein content rose continuously during stolon development. The adenosine diphosphoglucose pyrophosphorylase (AGPase) activity peaked in the initial swelling stage and stayed a relative high level in the middle swelling stage; sucrose synthase (SS), soluble starch synthase (SSS) and granule-bound starch synthase (GBSS) activities followed the same law that showed rising trends during stolon development. SS activity was significantly inversely related to sucrose content but had significantly positive relations with starch content, SSS and GBSS activities. Gibberellin (GA), indole-3-acetic acid (IAA) and zeatin riboside (ZR) peaked in the initial swelling stage and maintained high levels in the middle swelling stage; they then decreased significantly in the later swelling stage. A substantial increase was observed in abscisic acid (ABA) content until the middle swelling stage, followed by a significant reduction in the later swelling stage. The ratios of ABA to IAA, GA and ZR reached their lowest levels in the initial swelling stage. In conclusion, T. edulis stolon development is a process of new bulb morphogenesis along with the starch accumulation catalyzed by AGPase, SSS and GBSS, using the product of sucrose cleavage caused by SS. Initial low ABA content and low ratios of ABA to IAA, GA and ZR, together with the GA, IAA and ZR of high-content, soluble sugars worked more efficiently to induce new bulb formation.

      • Service life prediction of chloride-corrosive concrete under fatigue load

        Yang, Tao,Guan, Bowen,Liu, Guoqiang,Li, Jing,Pan, Yuanyuan,Jia, Yanshun,Zhao, Yongli Techno-Press 2019 Advances in concrete construction Vol.8 No.1

        Chloride corrosion has become the main factor of reducing the service life of reinforced concrete structures. The object of this paper is to propose a theoretical model that predicts the service life of chloride-corrosive concrete under fatigue load. In the process of modeling, the concrete is divided into two parts, microcrack and matrix. Taking the variation of mcirocrack area caused by fatigue load into account, an equation of chloride diffusion coefficient under fatigue load is established, and then the predictive model is developed based on Fick's second law. This model has an analytic solution and is reasonable in comparison to previous studies. Finally, some factors (chloride diffusion coefficient, surface chloride concentration and fatigue parameter) are analyzed to further investigate this model. The results indicate: the time to pit-to-crack transition and time to crack growth should not be neglected when predicting service life of concrete in strong corrosive condition; the type of fatigue loads also has a great impact on lifetime of concrete. In generally, this model is convenient to predict service life of chloride-corrosive concrete with different water to cement ratio, under different corrosive condition and under different types of fatigue load.

      • KCI등재

        Analysis of the Bacterial Community in a Full-scale Printing and Dyeing Wastewater Treatment System Based on T-RFLP and 454 Pyrosequencing

        Qingxiang Yang,Jia Wang,Xinkuan Han,Yuanyuan Xu,Dong Liu,Hongxin Hao,Xuemei L,Yuhui Guo,Tianqi Niu,Shiyue Qi 한국생물공학회 2014 Biotechnology and Bioprocess Engineering Vol.19 No.1

        In this study, the bacterial dynamics andstructure compositions in the two-stage biological processof a full-scale printing and dyeing wastewater (PDW)treatment system were traced and analyzed by terminalrestriction fragment length polymorphism (T-RFLP) and454 pyrosequencing techniques. T-RFLP analysis showedthat the microbial communities experienced significantvariation in the process of seed sludge adaptation to thePDW environments and were in constant evolution duringthe whole running period of the system, despite theconstant COD and color removal effects. Pyrosequencingresults indicated that the two-stage biological systemharbored rather diverse bacteria, with Proteobacteria beingthe predominant phylum during the steady running period,although its microbial compositions differed. The firststageaerobic tank was dominated by α-Proteobacteria(89.05% of Proteobacteria), whereas in the second-stageaerobic tank, β- and γ-Proteobacteria, besides α-Proteobacteria,were the dominant bacterial populations.

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