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- 저자 : YuHong Fu (검색결과 4 건)
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Yuhong Liang,Yan Chen,Binbin Chen,Baopeng Fan,Chaoren Yan,Yucan Fu 한국정밀공학회 2019 International Journal of Precision Engineering and Vol.20 No.7
Ultrasonic vibration assisted grinding (UVAG) is an effective method for edge trimming to improve the mechanical integrity of carbon fiber reinforced polymer (CFRP). However, due to the high heat resistance, abrasiveness and powdery chip of CFRP, serious tool clogging, rapid tool wear and poor surface are still considerable problems to the industry. In this paper, monolayer brazed diamond grinding tools with defined grain distribution are designed in order to solve the above problems. The maximum undeformed chip thickness based on UVAG was analyzed. A mathematical grinding force model was established based on monolayer brazed diamond tools. The UVAG experiments using different grain inter-row spacing diamond tools were carried out. The grinding force and surface morphology were investigated and compared. It was found that the predicted grinding force values were consistent with the experimental results. Additionally, the force was strongly related to the grain inter-row spacing. When employing the tool with the grain inter-row spacing of 1.2 mm, the grinding force was highest and the roughness of the surface was better due to more active grits and interaction-overlap areas.
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Adult Neurogenesis and Gliogenesis: Possible Mechanisms for Neurorestoration
Zoltán Rusznák,YuHong Fu,Willem Henskens,Emma Schofield,Woojin S. Kim 한국뇌신경과학회 2016 Experimental Neurobiology Vol.25 No.3
The subgranular zone (SGZ) and subventricular zone (SVZ) are developmental remnants of the germinal regions of the brain, hence they retain the ability to generate neuronal progenitor cells in adult life. Neurogenesis in adult brain has an adaptive function because newly produced neurons can integrate into and modify existing neuronal circuits. In contrast to the SGZ and SVZ, other brain regions have a lower capacity to produce new neurons, and this usually occurs via parenchymal and periventricular cell genesis. Compared to neurogenesis, gliogenesis occurs more prevalently in the adult mammalian brain. Under certain circumstances, interaction occurs between neurogenesis and gliogenesis, facilitating glial cells to transform into neuronal lineage. Therefore, modulating the balance between neurogenesis and gliogenesis may present a new perspective for neurorestoration, especially in diseases associated with altered neurogenesis and/or gliogenesis, cell loss, or disturbed homeostasis of cellular constitution. The present review discusses important neuroanatomical features of adult neurogenesis and gliogenesis, aiming to explore how these processes could be modulated toward functional repair of the adult brain.
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Yuzhi Yao,Tianzhu Long,Yuhong Pan,Yin Li,Ling Wu,Benjie Fu,Hongmin Ma 한국간호과학회 2021 Asian Nursing Research Vol.15 No.3
Purpose: This study aimed to describe the clinical response to five-step systematic therapy (FSST) in the management of plugged ducts and mastitis. FSST was a comprehensive milk stasis dredging treatment, which contained five steps to make the milk out of the plugged duct. Methods: This retrospective study included 922 breastfeeding women, 714 with plugged ducts, and 208 with mastitis who received FSST from June to September 2017. The breast pain score, swelling degree, and range of breast induration were recorded pre-FSST and post-FSST. Results: After a single FSST, pain score and swelling degree were significantly improved (both p < .001) in all cases. After FSST, the mean breast pain relief score was 1.69 ± 0.70, whereas the mean swelling fade away degree was 1.61 ± 0.62. In the subgroup analysis, pain score and swelling degree were significantly improved (both p < .001) in the plugged ducts group and the mastitis group. The score of pain relief in the plugged ducts group was less than that in the mastitis group (1.63 ± 0.68 vs. 1.91 ± 0.70, t = 5.30; p < .001), whereas improvement of swelling fade away was greater in the plugged ducts group than the mastitis group (1.65 ± 0.64 vs. 1.48 ± 0.56, t = 3.49; p = .001). The composition ratio of changes in induration range between the two groups was statistically different (Pearson c2 = 137.87, p < .001), of which more obvious improvement in the plugged ducts group than the mastitis group (c2 = 25.65, p < .001). Conclusion: FSST can relieve pain, reduce breast swelling and range of induration, and for plugged ducts or mastitis varied degree differently
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Odor Enrichment Increases Hippocampal Neuron Numbers in Mouse
Zoltán Rusznák,Gulgun Sengul,George Paxinos,김우진,YuHong Fu 한국뇌신경과학회 2018 Experimental Neurobiology Vol.27 No.2
The hippocampus and olfactory bulb incorporate new neurons migrating from neurogenic regions in the brain. Hippocampal atrophy is evident in numerous neurodegenerative disorders, and altered hippocampal neurogenesis is an early pathological event in Alzheimer’s disease. We hypothesized that hippocampal neurogenesis is affected by olfactory stimuli through the neural pathway of olfaction-related memory. In this study, we exposed mice to novel pleasant odors for three weeks and then assessed the number of neurons, non-neuronal cells (mainly glia) and proliferating cells in the hippocampus and olfactory bulb, using the isotropic fractionator method. We found that the odor enrichment significantly increased the neuronal cell numbers in the hippocampus, and promoted cell proliferation and neurogenesis in the olfactory bulb. In contrast, the glial cell numbers remained unchanged in both of the regions. Our results suggest that exposure to novel odor stimuli promotes hippocampal neurogenesis and support the idea that enriched environments may delay the onset or slow down the progression of neurodegenerative disorders.
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