소아신증후군 및 연소성 류마티스양 관절염 환자에서 Deflazacort(Calcort^(�))의 임상적 효과

마재숙,우영종,강경원,최기철 최신의학사 1994 最新醫學 Vol.37 No.8

장간막 지방종 1치험예

安永勳,馬泰烈,李哉昇,許銑 仁川基督病院 1977 仁川基督病院誌 Vol.1 No.2

皮膚科 外來 癩患者의 動態

宋浚榮,朴義守,徐舜鳳,徐基錫,河龍馬,孫在卿,金基洪,金蘭姬 大韓癩學會 1981 癩學 會誌 Vol.14 No.1

韓國人의 足紋에 關한 定量的 硏究

李金泳,吳永南,馬在濚,曺徵 全北大學校 基礎科學硏究所 1991 基礎科學 Vol.14 No.1

한국인의 정상 남자 112명, 여자 118명 총 230명의 460足蹠에 나타난 皮紋을 분석하여 다음과 같은 결과를 얻었다. 1) 족척의 중간부의 降線 方向은 橫行(76.5%), 輕度의 비골측 近位傾斜(11.5%), 輕度의 비골측 遠位傾斜(11.1%), 뚜렷한 비골측 遠位傾斜(0.9%)의 순으로 나타났으며 중간부의 융선 배열에 대한 대칭 빈도는 63.9%로 나타났다. 2) 무지구부 紋形은 원위측 제상문(64.8%), 와상문(20.2%), 개방문(5.9%)의 순으로 나타났으며 무지구에 나타난 대칭 빈도는 83.2%이었다. 3) 趾間部 紋形은 Ⅱ지간부에서는 개방문(73.7%), 원위측 제상문(22.2%), 근위측 제상문(3.3%), 와상문(0.9%)의 순으로, Ⅲ지간부에서는 개방문(54.8%), 원위측 제상문(41.7%), 와상문(2.4%), 근위측 제상문(1.1%)의 순으로, Ⅳ지간부에서는 개방문(81.7%), 원위측 제상문(17.4%), 와상문(0.9%)의 순으로 나타났다. 4) 趾間部 降線數는 a-b 57.76, b-c 70.74, c-d 75.09이며 남녀 사이, 또는 양족 사이에는 통계적으로 유의한 차이가 없었다(P>0.01). The dermatoglyphic patterns of the hands and feet form during early fetal life and thereafter remain essentially unchanged. These traits are useful to study genetics and environmental factors that influence prenatal life and used in practice for personal identification and diagnosis of some diseases. The students of 112 male and 118 female were tested for the patterns of plantar regions. The most common patterns were open fields in the four interdigital areas and the frequency of the mirror pattern on them was 57.2%. For a-b, b-c and c-d ridge counts of the plantar interdigital areas sampled from 105 male and 109 female students, the nonsignificances were found between both sexes and between both feet.

小兒의 Guillain-Barre 症候群에 對한 臨床的 觀察

閔惠蘭,禹永琮,馬在淅 全南大醫大 1986 전남의대학술지 Vol.23 No.3

Analysis of population structure and genetic diversity in Rubus species using SSR markers

Jae Young Song,Gi-An Lee,Sok-Young Lee,Kyung-Ho Ma,Do Yoon Hyun,Chang Young Kim,Yu-mi Choi,Yeon-Gyu Kim,Myung-Chul Lee 한국육종학회 2012 한국육종학회 심포지엄 Vol.2012 No.07

The genus Rubus belongs to the Rosaceae family and is comprised of 600-800 species distributed worldwide. Understanding the genetic relationships and genetic structure in Rubus species is important for enabling efficient management, conservation, characterization and utilization of the species. However, as a minor crop, genetic research foundation was limited to explore genetic diversity and relationships in Rubus species. The present study shows the results of application SSR markers that were developed from SSR-enriched libraries of the one Rubus species (Rubus coreanus Mique.) in our previous study. We used 34 polymorphic microsatellite markers to analysis of genetic diversity within the Rubus species, including redraspberry, blackraspberry, blackberry and mountainberry. All the 34 SSR primers pairs produced 483 polymorphic and reproducible amplification fragments. The largest number of alleles per primer pair was confirmed at GB-RC-167, GB-RC-100, GB-RC-076 and GB-RC-245, which contained 26, 25, 23 and 21, respectively. An average value of polymorphic information contents (PIC) were 0.74 with a range of 0.36 to 0.92. Population structure and phylogenetic analyses showed that all Rubus species formed three largely distinct clusters, which were confirmed by principal coordinate analysis (PCoA). We obtained the results that the developed SSR markers showed a substantial degree of genetic diversity in the various Rubus species distributed in Korea.

차나무의 품종, 부위, 채취시기에 따른 향기생성 효소의 활성과 향기배당체의 함량

정재천(Jae-Cheon Jeong),최정연(Jeong-Youn Choi),최문희(Moon-Hui Choi),손영란(Young-Lan Son),조정용(Jeong-Yong Cho),김선재(Seon-Jae Kim),문제학(Jae-Hak Moon),박근형(Keun-Hyung Park),마승진(Seung-Jin Ma) 한국차학회 2012 한국차학회지 Vol.18 No.4

Enzymatic activities and amounts of aromatic precursors, which are related with aroma formation in fermanted tea, were indirectly measured in vanious cultivars (Korean native cultivar, Taicha No.12, Yabukita), harvest time (May, July, September), and parts (aged leaves, young leaves, stem) by means of crude enzyme assay. Enzyme activities related to aroma formation in stems and young leaves were higher than those in aged leaves. Activities in parts harvested in September and July were higher than in those harvested in May. Total amounts of aromatic precursors were higher in young leaves than those in aged leaves from each cultivar. Amounts of precursors of geraniol and methyl salicylate were much higher in each part of Taicha No.12 than those of Yabukita, although much greater amounts of benzyl alcohol and 2-phenylethanol were liberated from Yabukita.

Down-regulation of xenobiotics metabolic enzymes in hepatocellular carcinogenesis

Ma Rie Yeo,Young Mi Na,Dong Kyu Kim,Jae Youn Cheong,Jung A Lee,Hee Jeong Wang,Young Bae Kim,Young Ki Paik,Sung Won Cho 대한간학회 2009 Clinical and Molecular Hepatology(대한간학회지) Vol.15 No.3(S)

Diversity Capturing Comparison by Combinations among Clustering Methods, Allocation Strategies, and Sampling Strategies in Establishment Core-Sets of Mungbean (Vigna radiata) Germplasm Preserved in NAC Genebank

Jae-Gyun Gwag,Se-Jong Oh,Ho-Cheol Ko,Kyung-Ho Ma,Gyu-Taek Cho,Gi-An Lee,Sok-Young Lee,Young-Jin Park 한국국제농업개발학회 2012 韓國國際農業開發學會誌 Vol.24 No.4

1. 세계 26개국에서 도입된 녹두 유전자원 705점에 대하여16개의 형태적 형질 특성을 이용하여 각각 두 가지의 군집방법, 핵심집단 자원수 결정방법 및 표본추출 방법을 조합하여 총8개의 핵심집단(SUNPR, SUNPPr, UNPR, UNPPr, SUNLR, SUNLPr, UNLR, UNLPr)을 작성하여 원수집단과 비교한바 8개핵심집단 모두 원수집단과는 분산과 평균치에서 차이가 없었다. 2. Nei의 다양성지수는 8개 핵심집단 모두 원수집단 보다높았고, 특히 UNLPr이 가장 높았으며, UNPR은 다른 핵심집단에 비하여 상대적으로 낮은 지수를 보였다. 3. 원수집단과 핵심집단간 자원분포의 동질성을 파악하기 위하여 카이자승 검증을 한 결과 12개 양적형질과 1개의 질적형질(종피색)은 모든 핵심집단이 동질분포를 보였으나 3개의질적 형질 (배축색, 종피광택, 생육습성)은 핵심집단에 따라서동질분포를 하는 것과 그렇지 않은 것이 있었으며, 8개 핵심집단 중 UNPPr은 동질성이 가장 높았다. 평균차율(MD%)과일치율(CR%)은 8개 핵심집단 모두 유의한 수준을 보였다. 4. 8개의 모든 핵심집단이 원수집단과 평균치에서 차이가 없고, 높은 다양성을 과 동질한 분포를 보이며, 평균차율(MD%)과 일치율(CR%)이 유의한 수준을 보여 원수집단의 다양성을잘 나타내는 것으로 해석되었다. 5. 핵심수집단 크기(10%와 15%)에 따른 다양성은 유의한차이가 없었으며, 8개의 핵심집단 중 평균치, 동질분포, 일치율 및 도복내성을 고려할 때 UNPPr이 가장 좋은 핵심집단으로 사료되었다. A core collection is a subset chosen to represent the diversity of a collection with a minimum of redundancies and is established to improve the conservation and use of genetic resources. In this study, eight core subsets were established by combinations among two clustering methods (SUN, UN), two allocation strategies (P, L), and two sampling strategies (R, Pr) using morphological traits and were compared with entire collection by variance, means, Nei's diversity index, goodness of fit, the mean difference percentage (MD%), the variance difference percentage (VD%), coincidence rate (CR%), and the variable rate (VR%) of traits. The variances between entire and eight core subsets was homogeneous for all the traits of all core subsets by Levene's test both 10% and 15% sample sizes and the means between entire and 8 core subsets were found to be non-significant by Newman-Keuls test for all traits of all core subsets both 10% and 15% sample sizes. The average Nei's diversity index of the eight core subsets showed higher than the entire collection. UPGMA NTSYS Logarithmic Pragmatic (UNLPr) showed the highest average Nei's diversity index, and Logarithmic (L) allocation strategy showed higher average diversity index than Proportional (P) strategy in both 10% and 15% sample size. Frequency distribution between the entire collection and the eight core subsets using chi square test showed homogeneous distribution for 13 traits of 16 traits. The proportional allocation strategy showed relatively more homogeneous distribution than the logarithmic allocation strategy for the three qualitative traits; hypocotyl color (HC), luster on seed surface (LS), and growth habit (GH). All the core subsets had significant values of MD% and CR%. Although decrease of VD% and increase of CR% according to sample size increase from 10% to 15%, there was no significant difference between 10% and 15% sample size. Considering all parameters such as means, homogeneous distribution, VD%, CR%, average lodging tolerance, and bruchid resistance, UNPPr is the best among eight core subsets. Present result suggested that with regardless of clustering methods, if group size can be adjusted according to group diversity and utility, better core subset will be established so that original purposes of effective utilization and enhancement of the genetic diversity will be increased.

Analysis of Genetic Diversity and Population Structure of Buckwheat (Fagopyrum esculentum Moench) Landraces of Korea Using SSR Markers

Song, Jae-Young,Lee, Gi-An,Yoon, Mun-Sup,Ma, Kyung-Ho,Choi, Yu-Mi,Lee, Jung-Ro,Jung, Yeon-Ju,Park, Hong-Jae,Kim, Chung-Kon,Lee, Myung-Chul The Plant Resources Society of Korea 2011 한국자원식물학회지 Vol.24 No.6

Buckwheat (Fagopyrum esculentum Moench), one of the minor crops grown in Korea belonging to the Polygonaceae family, is an annual crop widely cultivated in Asia, Europe, and America and has a character of outcrossing and self-incompatibility. The objective of this study was to analyze the genetic variability, phylogenetic relationships and population structure of buckwheat landraces of Korea using SSR markers. Ten microsatellite markers have been detected from a total of 79 alleles among the 179 buckwheat accessions were collected from Korea. The number of allele per marker locus ($N_A$) ranged from 2 (GB-FE-001, GB-FE-043 and GB-FE-055) to 31 (GB-FE-035) with an average of 7.9 alleles. GB-FE-035 was the most polymorphic with the highest PIC value 0.93. Major allele frequencies ($M_{AF}$) for the 10 polymorphic loci varied from 0.12 to 0.97 with a mean allele frequency of 0.57. The expected heterozygosity ($H_E$) values ranged from 0.05 to 0.94 with an average of 0.53. The observed heterozygosity ($H_O$) ranged from 0.06 to 0.92 with an average of 0.42. The overall polymorphic information contents (PIC) values ranged from 0.05 to 0.93 with an average of 0.48. The landrace accessions of buckwheat used in the present study were not distinctly grouped according to geographic distribution. The study concludes that the results revealed genetic differentiation was low according to the geographic region because of outcrossing and self-incompatibility. We reported that our analyses on the genetic diversity of common buckwheat cultivars of Korea were performed by using of microsatellite markers.