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Impact of Liver Fibrosis on Long-Term Outcome in Ischemic Stroke Patients
( Seung Up Kim ),( Minyoul Baik ),( Sungwoo Kang ),( Hyung Jong Park ),( Hyo Suk Nam ),( Ji Hoe Heo ),( Beom Kyung Kim ),( Jun Yong Park ),( Do Young Kim ),( Sang Hoon Ahn ),( Kwang-hyub Han ),( Young 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: To investigate whether there are differences in long-term all-cause and cardiovascular mortality by the burden of liver fibrosis or steatosis in patients with ischemic stroke or transient ischemic attack (TIA). Methods: Consecutive patients with acute ischemic stroke or TIA, who underwent transient elastography (TE) from January 2014 to December 2014, were considered eligible. The influence of liver fibrosis or steatosis, assessed using TE, on long-term outcomes was investigated using Cox proportional hazard models. Results: Among 395 patients included in this study, there were 37 (9%) patients with significant fibrosis (>8.0 kPa) and 164 (41.5%) patients with fatty liver (>250 dB/m). During the follow-up (median 2.7 years), all-cause and cardiovascular mortality occurred in 28 (7.1%) and 20 (5.1%) patients. On multivariate analyses, significant liver fibrosis was independently associated with increased risk of all-cause (HR 8.14, 95% CI 3.03-21.90, P< 0.001) and cardiovascular (HR 4.04, 95% CI 1.17-13.98, P=0.028) mortality, whereas fatty liver was not (all > p 0.05) Conclusions: This study demonstrated that the burden of liver fibrosis, not steatosis assessed on TE was an independent predictor of all-cause and cardiovascular mortality during long-term follow-up in patient with ischemic stroke.
金成完,姜信業,趙成燮,成瓚鏞 충남대학교 농업과학연구소 1983 農業技術硏究報告 Vol.10 No.2
To study the effect of foaming agent on the production and property of light weight concrete, the tests of compressive, tensile, bending strengths and absorption rates of mortar were done under the different mixing ratio with J, A and D foaming agents. The results obtained were summarized as follows : 1. The strengths were decreased in richer mixing ratio and more addition of foaming agent. The decrease of strengths was the greatest at the level of 0.75% of foaming agent. The decreasing rate of strengths was in order of J, A and D foaming agent. 2. At the mixing ratio of 1 : 1, σ_28 and 0.75% of foaming agent, the compressive strength was decreased up to 34.9% by D, 47.8% by A and 86,8% by J foaming agent, respectively, the tensile strength was decreased up to 14.8% by D, 20.2% by A and 77.9% by J foaming agent, respectively, bending strength was decreased up to 19.9% by D, 35.0% by A and 79.1% by J foaming agent, respectively. The decrease of compressive strength was more severe than that of tensile and bending strengths. 3. The absorption rates were increased in poorer mixing ratio and more addition of foaming agent. The absorption rate was significantly higher at the early stage of immersed water. The absorption rate was in order of J, A and D foaming agent. 4. The decrease of strengths was inevitable in cement-mortar with foaming agent, but the cement mortar with foaming agent has such the properties of the light-weight, lnsulation, Keeping-warmth, sound proof and fire-proof that if could be utilized to the constructions which need low strengths.
A Low Complexity Multi-Packet Reception Technique for Wireless Ad Hoc Networks
Bang Chul Jung,Yong-Up Jang,Min Suk Kang,Tae-Won Ban 보안공학연구지원센터 2014 International Journal of Control and Automation Vol.7 No.10
In this paper, a practical multi-packet reception technique is proposed for wireless ad hoc networks in which concurrent transmissions generally occur. In practical systems, these transmissions are performed without pre-compensation of time and frequency offsets before transmission due to decentralized nature of ad hoc networks. We first derive an optimal asynchronous joint detection (OAJD) technique for concurrent transmissions by considering time and frequency offsets among the multiple received packets. Furthermore, we propose a suboptimal asynchronous joint detection (SAJD) technique with log-likelihood ratio by utilizing the fact that practical pulse-shaping filters including raised cosine filter fall down beyond the number of symbol times. The proposed SAJD yields better performance than that of the successive interference cancellation (SIC) technique which successively decodes a packet with the strongest signal and cancels a decoded packet from multiple received packets.
Kang, Se Hun,Kim, Do Young,Jeon, Soung Min,Ahn, Sang Hoon,Park, Jun Yong,Kim, Seung Up,Kim, Ja Kyung,Lee, Kwan Sik,Chon, Chae Yoon,Han, Kwang-Hyub Lippincott Williams Wilkins, Inc. 2012 European journal of gastroenterology & hepatology Vol.24 No.7
OBJECTIVE: α-Fetoprotein (AFP) and prothrombin induced by the absence of vitamin K or antagonist-II (PIVKA-II) are useful tumor markers for hepatocellular carcinoma (HCC). However, little is known about the clinical characteristics and prognosis of HCC with different levels of AFP and PIVKA-II. METHODS: Consecutive 1447 HCC patients were assigned to four groups according to the cutoff values of AFP (400 ng/ml) and PIVKA-II (100 mAU/ml): both values high (AP), one of the values high (Ap and aP), and both values low (ap). The clinical characteristics and the prognosis of group ap were compared with those of the other groups. RESULTS: HCC patients in group ap were more asymptomatic at diagnosis, and had smaller size, fewer numbers, and earlier stages of HCC, and more preserved liver functions (all, P<0.001). The survival rate of group ap was significantly higher than those of the other groups (P<0.001). In multivariate analysis, the combined status of AFP and PIVKA-II values were independent predictors for survival (P<0.001), together with tumor size, number, portal vein thrombosis, Child–Pugh class, and treatment modality. CONCLUSION: HCC patients with low values of both AFP and PIVKA-II had more favorable clinical characteristics and showed a better prognosis than those with elevated levels of AFP or PIVKA-II.
姜信業,金成完,成瓚鏞 충남대학교 농업과학연구소 1986 農業技術硏究報告 Vol.13 No.1
This study was performed to obtain the basic data which can be applied to the use of concretes. The data was based on the properties of concrectes depending upon water-cement ratios and addings to compare those of plain concrete. The results obtained were summarized as follows; 1. In case the proper quantity of water reducing agent was added, unit weight of water is decreased to 12.9% with WR-LG of water reducing set standarding agent and to 8.6% with HF-SP of high fluid agent and to 17.2% with AH-WR of water reducing set accelerating agent, respectively, as compared with plain concrete. With the increase of water reducing agent content unit weight of water was greatly decreased. 2. The adding rate of water reducing agent which produce maximum strength was 0.2% with WR-LG and 0.4% with HF-SP and AH-WR, respectively. The increasing rates of strengths were showed that WR-LG is 24.1% and that HF-SP is 41.8% and that AH-WR is 43.3%, respectively, as compared with plain concrete. 3. The correlations between compressive and tensile strength were highly significant as a straight line. the multiple regression equations of compressive and tensile strength were computed with the variables of curing age and addition of water reducing agent. They were highly significant. 4. In case the proper quantity of water reducing agent was added, the correlations between water-cement ratio and compressive strength were highly significant as a straight line. The increasing rates of strength were showed higher than the decreasing rates of water cement-ratio.
( Kang Pyo Kim ),( Nam Woo Kwon ),( Beom Kyung Kim ),( Seung Up Kim ),( Do Young Kim ),( Sang Hoon Ahn ),( Kwang Hyub Han ),( Chae Yoon Chon ),( Jun Yong Park ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1
Background: With wide use of vaccination and antiviral agents against hepatitis B virus (HBV) infection, epidemiologic characteristics of HBV-infected patients have changed substantially for several decades in South Korea, however, recent data are lacking. Hence, we reviewed the recent clinical characteristics of patients with chronic hepatitis B (CHB). Methods: From January 2010 to December 2010, we studied 5,262 consecutive HBV-infected patients who visited in Severance Hospital. Data concerning demographic profiles, laboratory findings about viral activity, and antiviral therapy were gathered. Results: Among the whole population, the median age was 51.0 and 66.0% were male. 1,788 (34.0%) had positive HBeAg and the median ALT level was 31.0 (2, 4700) IU/ml and 1,560 (29.6%) patients had family history of HBV-related liver disease. Regarding viral replication status, 297 (5%) patients were in immune tolerance phase, 2,195 (42%) in inactive phase, and the remaining 2,770 (53%) patients were in active CHB (eiher immune clearance or reactivation phase). Liver cirrhosis was diagnosed in 2,065 patients, among them, 611 (29.6%) patients had positive HBeAg, and 576 patients had experienced decompensation events including ascites, variceal bleeding, and hepatic encephalopathy. Hepatocellular carcinoma was diagnosed in 1,268 patients. Patients with HCC increased as they get older, especially after age of forty for male and after fifty for female. The male patients had a significantly higher ratio of the HCC than female patients did (78.7% vs. 21.3%, respectively, p<0.001). Conclusions: The study result shows that epidemiologic characteristics of CHB are male, elder, HBeAg negative dominant. The further studies are required to investigate the overall epidemiology of HBV infection in Korea.
( Kang Pyo Kim ),( Nam Woo Kwon ),( Beom Kyung Kim ),( Seung Up Kim ),( Do Young Kim ),( Sang Hoon Ahn ),( Kwang Hyub Han ),( Chae Yoon Chon ),( Jun Yong Park ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.-
Background: With wide use of vaccination and antiviral agents against hepatitis B virus (HBV) infection, epidemiologic characteristics of HBV-infected patients have changed substantially for several decades in South Korea, however, recent data are lacking. Hence, we reviewed the recent clinical characteristics of patients with chronic hepatitis B (CHB). Methods: From January 2010 to December 2010, we studied 5,262 consecutive HBV-infected patients who visited in Severance Hospital. Data concerning demographic profiles, laboratory findings about viral activity, and antiviral therapy were gathered. Results: Among the whole population, the median age was 51.0 and 66.0% were male. 1,788 (34.0%) had positive HBeAg and the median ALT level was 31.0 (2, 4700) IU/ml and 1,560 (29.6%) patients had family history of HBV-related liver disease. Regarding viral replication status, 297 (5%) patients were in immune tolerance phase, 2,195 (42%) in inactive phase, and the remaining 2,770 (53%) patients were in active CHB (either immune clearance or reactivation phase). Liver cirrhosis was diagnosed in 2,065 patients, among them, 611 (29.6%) patients had positive HBeAg, and 576 patients had experienced decompensation events including ascites, variceal bleeding, and hepatic encephalopathy. Hepatocellular carcinoma was diagnosed in 1,268 patients. Patients with HCC increased as they get older, especially after age of forty for male and after fifty for female. The male patients had a significantly higher ratio of the HCC than female patients did (78.7% vs. 21.3%, respectively, p<0.001). Conclusions: The study result shows that epidemiologic characteristics of CHB are male, elder, HBeAg negative dominant. The further studies are required to investigate the overall epidemiology of HBV infection in Korea.
박용업(Yong-Up Park),강문호(Moon-Ho Kang),윤기갑(Gi-Gap Yoon) 대한전기학회 2006 대한전기학회 학술대회 논문집 Vol.2006 No.7
The dispersed generation is recently increased introduction for the energy supply rationalization and effective management of power system. But the dispersed generation causes to the various trouble that isn't occurred in the past, for example, the two way systems have an effect on the mistake action of protection equipment and the power quality. In this paper, we research the influence on the harmonic when the dispersed generation is interconnected with distribution system. To achievement, we construct the interconnecting dispersed generation and distribution system which is applied to the permission of harmonic emission. After that, we simulate about the harmonic of distribution system interconnection dispersed generation by the PSCAD/EMTDC analyzing transient state of the power system.