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- 저자 : Yiling Zheng (검색결과 3 건)
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Yiling Zheng,Liming Wang,Fan Wu,Weiqi Rong,Yunhe Liu,Kai Zhang,Jianxiong Wu 대한외과학회 2020 Annals of Surgical Treatment and Research(ASRT) Vol.98 No.5
Purpose: To evaluate the safety and effectiveness of an enhanced recovery after surgery (ERAS) programme after curative liver resection in cirrhotic hepatocellular carcinoma (HCC) patients. Methods: One hundred sixty-two patients were enrolled in the study; 80 patients whose data were collected prospectively were assigned to the ERAS group, and 82 patients whose data were collected retrospectively were assigned to the control group. Preoperative clinicopathologic factors, surgical factors, and postoperative outcomes of the 2 groups were compared. Logistic regression was applied to explore potential predictors of hospital stay and morbidity. Results: The postoperative hospital stay, postoperative complication rate, and recovery of liver function on postoperative day 5 seemed to be better in the ERAS group. The composition of complications was different in the 2 groups; pleural effusion and postoperative ascites were more common in the control group, and indocyanine green retention at 15 minutes, operation time, preoperative alanine aminotransferase, and number of liver segmentectomies were associated with postoperative complications rather than ERAS intervention. Conclusion: The ERAS programme is safe and effective for HCC patients with chronic liver disease undergoing hepatectomy, but it seems that surgical factors, such as operation type, have a greater impact on morbidity than other factors. Operative characteristics such as the method of blood loss control and the volume of liver resection should be augmented into ERAS protocol of hepatectomy.
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Expression Profile of Neuro-Endocrine-Immune Network in Rats with Vascular Endothelial Dysfunction
Lujin Li,Yiling Wu,Qingshan Zheng,Zhenghua Jia,Ling Xu 대한약리학회 2014 The Korean Journal of Physiology & Pharmacology Vol.18 No.2
This study was to determine the correlation between endothelial function and neuro-endocrineimmune(NEI) network through observing the changes of NEI network under the different endothelialdysfunction models. Three endothelial dysfunction models were established in male Wistar rats afterexposure to homocysteine (Hcy), high fat diet (HFD) and Hcy+HFD. The results showed that therewas endothelial dysfunction in all three models with varying degrees. However, the expression of NEInetwork was totally different. Interestingly, treatment with simvastatin was able to improve vascularendothelial function and restored the imbalance of the NEI network, observed in the Hcy+HFD group. The results indicated that NEI network may have a strong association with endothelial function, andthis relationship can be used to distinguish different risk factors and evaluate drug effects.
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Expression Profile of Neuro-Endocrine-Immune Network in Rats with Vascular Endothelial Dysfunction
Li, Lujin,Jia, Zhenghua,Xu, Ling,Wu, Yiling,Zheng, Qingshan The Korean Society of Pharmacology 2014 The Korean Journal of Physiology & Pharmacology Vol.18 No.2
This study was to determine the correlation between endothelial function and neuro-endocrine-immune (NEI) network through observing the changes of NEI network under the different endothelial dysfunction models. Three endothelial dysfunction models were established in male Wistar rats after exposure to homocysteine (Hcy), high fat diet (HFD) and Hcy+HFD. The results showed that there was endothelial dysfunction in all three models with varying degrees. However, the expression of NEI network was totally different. Interestingly, treatment with simvastatin was able to improve vascular endothelial function and restored the imbalance of the NEI network, observed in the Hcy+HFD group. The results indicated that NEI network may have a strong association with endothelial function, and this relationship can be used to distinguish different risk factors and evaluate drug effects.
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