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      • KCI등재후보

        Effects of Oxidation and Nitridation Temperatures on Electrical Properties of Sputtered Zr Thin Film Based on Si in N2O Ambient

        Yew Hoong Wong,Kuan Yew Cheong 대한금속·재료학회 2012 ELECTRONIC MATERIALS LETTERS Vol.8 No.1

        The effects of oxidation and nitridation temperatures (500-1100°C) on metal-oxide-semiconductor charac-teristics of sputtered Zr thin film on Si in N2O ambient have been systematically investigated. The sample being oxidized and nitrided at 700°C has demonstrated the highest effective dielectric constant of 21.82 and electrical breakdown field of 13.6 MV cm−1at a current density of 10−6A cm−2. This is attributed to the lowest effective oxide charge, interface-trap density, and total interface-trap density of the oxide and the highest barrier height of conduction band offset between the oxide and semiconductor when compared with others.

      • KCI등재후보

        Residual Contrast Media in the Azygos Vein: An Uncommon Pseudolesion in Computed Tomography Coronary Angiography

        Yew Min Sen,Kaur Rajinderdeep,Lee Wan Ling,Omar Hider Bin,Lee Yeong Shyan 아시아심장혈관영상의학회 2022 Cardiovascular Imaging Asia Vol.6 No.3

        Contrast reflux from superior vena cava into azygos system may be mistaken for pathology. We report a case occurring during CT coronary angiography (CTCA) causing diagnostic uncertainty. A linear hyperdensity anterior and left of the upper thoracic vertebrae was seen during CTCA and mistaken for abnormal calcification. However, this was not seen on non-contrasted coronary calcium images. The hyperdensity correlated to the location of the unenhanced azygos vein seen on test bolus images. Although reported in CT pulmonary angiography, contrast in the azygos system is less common in CTCAs as the longer scan delay allows contrast washout. However, right arm contrast injection, the default for CTCA, is an association. Moreover, right heart and pericardial diseases are also potential causes. Cardiac imagers should be aware of this potential pitfall.

      • KCI등재후보

        Recurrent Paroxysmal Atrial Tachycardia Triggered by Deep Inspiration During Contrast Enhanced Computed Tomography Coronary Angiography

        Yew Min Sen,Tan Kenny Wee Kian 아시아심장혈관영상의학회 2022 Cardiovascular Imaging Asia Vol.6 No.1

        A 64-year-old lady underwent CT coronary angiography. Rhythm tracing showed initial sinus bradycardia with sudden onset of atrial tachycardia (AT) during contrast administration and breath-holding, which resolved almost immediately after the scan. Motion artifacts were seen. This recurred during a repeat attempt, but self-terminated before the images were acquired. We hypothesize that the AT may be contributed by both respiratory cycle-dependent AT and use of iodinated contrast. Although rare and not previously reported in the setting of cardiac CT, we demonstrated that respiratory cycle-dependent AT can be triggered by conditions universally present during coronary CT, namely the need for deep inspiration, breath holding and intravenous iodinated contrast. This poses a unique challenge for coronary CT imaging and greater awareness of this entity is needed amongst CT technologists and physicians.

      • SCIESCOPUS

        Hazardless Biomedical Sensing Data Transmission Using VLC

        Yew-Kiat Cheong,Xiao-Wei Ng,Wan-Young Chung IEEE 2013 IEEE SENSORS JOURNAL Vol.13 No.9

        <P>The implementation of radio-frequency communication technologies in biomedical or healthcare applications involves multiple issues such as interference with precision medical instruments and human health hazard because of electromagnetic waves. A novel visible light communication technology for transmitting and monitoring biomedical data is presented. White beam light emitting diodes are used as optical information emitters for efficiently transmitting biomedical data such as patient information text and wavelike body sensor signals. ON/OFF keying modulation is used to modulate the data onto the visible light beam, and a high-speed p-i-n photo-detector is employed at the receiver. Experimental analysis of the data collected using this system demonstrates the effectiveness of the proposed method.</P>

      • SMC Reliable Design for T-S Model-Based Systems

        Yew-Wen Liang,Sheng-Dong Xu,Der-Cherng Liaw,Cheng-Chang Chen,Li-Wei Ting 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8

        This paper studies the robust reliable control issues based on the Takagi-Sugeno (T-S) fuzzy system modeling method and the sliding mode control (SMC) technique. The combined scheme is shown to have the merits of both approaches. It not only alleviates the on-line computational burden by using the T-S fuzzy system model to approximate the original nonlinear one (since most of the system parameters of the T-S model can be computed off-line) but it also preserves the advantages of rapid response and robustness of the SMC schemes. Moreover, the combined scheme does not require on-line computation of any nonlinear term of the original dynamics and the increase in the partition number of the region of premise variables does not create extra on-line computational burdens for the scheme. Under the design, the control mission can continue safely without prompt external support even when the susceptible actuators fail to operate. The proposed analytical results are also applied to the attitude control of a spacecraft. Simulation results demonstrate the benefits of the proposed scheme.

      • KCI등재

        A Review of Sirtuin Inhibitors in Therapeutics, Pharmaceutics, and Plant Research

        Yew Lee(이유) 한국생명과학회 2020 생명과학회지 Vol.30 No.1

        서투인 억제제는 유형 III 히스톤 데아세틸라제(HDAC)인 서투인을 억제하는 화합물이며, 약제학적 및 치료학적 가치를 갖는다. 합성 서투인 억제제는 효모 S. cerevisiae 에서 세포-기반 스크린을 사용하여 발견되었고 특성화 되었으며 서투인의 기능과 관련된 노화, 발암 및 당뇨병을 연구하는데 사용되었다. 의학 분야에서 합성 서투인 억제제는 보다 강력한 효능과 특이성을 얻기 위해 개발되어 왔다. 니코틴아미드 및 티오아세틸리신 함유 화합물, β-나프톨 함유화합물, 인돌 유도체. 수마린, 테노빈 및 그 유사체가 개발 되었다. 서투인 억제제는 식물 발달에 영향을 미치는 것으로 밝혀졌으며 식물의 화학적 유전학에 사용되었다. 그러나, 시르티놀-내성 돌연변이 체는 알데히드 옥시다제에 대한 몰리브돕테린 보조인자의 생합성 유전자에 돌연변이가 있었다. 일부 천연 플라보노이드, 카테킨 유도체 및 퀴르세틴 유도체는 서투인 억제제로서 작용하며 치료 목적을 위한 보다 강력한 억제제를 찾기위해 연구 되고 있다. 이 리뷰에서, 서투인을 소개하면서 치료제에서 개발된 서투인 억제제를 소개한다. 서투인 억제제인 서티놀은 식물에서 화학적 유전학에 예기치 않게 사용되었습니다. 보다 강력하고 선택적인 서투인 억제제가 치료제에서 개발되어야 하고, 약학에서 개발된 다른 서투인 억제제는 식물에서 보다 진정한 서투인을 찾기위해 사용되어야 한다. Sirtuin inhibitors are pharmaceutically and therapeutically valuable compounds that inhibit sirtuin, a type III histone deacetylase. Synthetic sirtuin inhibitors were discovered and characterized using cell-based screens in yeast (Saccharomyces cerevisiae) and have been used in the study of aging, carcinogenesis, and diabetes, all of which are related to sirtuin function. For medical applications, synthetic inhibitors have been further developed for increased potency and specificity, including compounds containing nicotinamide, thioacetyl lysine, β-naphthol, and indole derivatives. Suramin, tenovin, and their analogues were developed as a result. Sirtuin inhibitors were found to affect organic development and have been used to genetically modify plants, although a sirtinol-resistant mutation in the biosynthesis of a molybdopterin cofactor for an aldehyde oxidase has been identified. Some natural flavonoids, and catechin and quercetin derivatives also act as sirtuin inhibitors have been studied to identify a more potent inhibitor for therapeutic purposes. In this review, sirtuin is introduced and the therapeutic inhibitors that have been developed are presented, particularly sirtinol which has been used for genetic modification in plants though it was not designed to be so. Sirtuin inhibitors with greater potency and selectivity are required and those developed in pharmaceutics should be used in plant research to identify more authentic sirtuins in plants.

      • Fast Drone Detection using SSD and YoloV3

        Yew Ji Hao,Lee Koon Teck,Chua Ying Xiang,Enoch Jeevanraj,Sutthiphong Srigrarom 제어로봇시스템학회 2021 제어로봇시스템학회 국제학술대회 논문집 Vol.2021 No.10

        This paper aims to introduce the method of detection of high-speed drones using both Single Shot Detector (SSD) and YOLOv3 (You Only Look Once)v3. After conducting experiments and obtaining footage of the fast-flying drones, the software and algorithms are being put to the test. In a motion detector, there are 3 main fundamentals - unmanned aerial vehicle (UAV) detection, UAV identification and tracking of the UAV, which will be introduced as a preliminary UAV detection system to spark of the use of other more advanced image recognition based detector. The alternative of using SSD and YOLOv3 will be the main discussion to target high-speed drones.

      • KCI등재

        of Midcourse Guidance Laws via a Combination of Fuzzy and SMC Approaches

        Yew-Wen Liang,Chun-Hone Chen,Der-Cherng Liaw,Shih-Tse Chang,Sheng-Dong Xu 제어·로봇·시스템학회 2010 International Journal of Control, Automation, and Vol.8 No.2

        Issues regarding the design of midcourse guidance laws for antimissiles are addressed. The antimissile is expected to be guided to a place with a desired direction, where a ballistic missile is predicted to pass in the reverse direction, so that the target can be easily found and locked for terminal interception. The predicted location and direction of a ballistic missile may vary with time, due to information update using a trajectory prediction algorithm. To fulfill the guidance performance, the guidance laws are designed by combining the Takagi-Sugeno (T-S) fuzzy approach and the Sliding Mode Control (SMC) technique. Under the designed guidance law, it is shown that the antimissile is able to be efficiently guided to a specified location and direction, even when the existence of uncertainties and disturbances.

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