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Kuijing Song,Xinquan Liu,Yukai Ji,Yong Wei,Junrui Luo,Fei Liu,Dashuang Liu,Zhihong Zhong 대한금속·재료학회 2023 METALS AND MATERIALS International Vol.29 No.4
Aluminum/magnesium (Al/Mg) alloys have good metallurgical compatibility as well as similar melting and recrystallizationtemperatures. Therefore, the formation of deleterious IMCs is considered as a major problem in dissimilar Al/Mgalloys joining. In this paper, the metallurgical reaction behavior and atomic diffusion in Al/Mg solid state joining interfaceare studied. Based on the thermodynamic, kinetic and crystallographic characteristics of ordered phase transformation andatomic diffusion database, a phase field calculation framework of the polycrystalline β–Al3Mg2 and γ–Al12Mg17 evolutionis developed. Diffusivity, D and interface mobility, M, which significant kinetic parameters are defined as alloy compositionsand joining conditions dependent. By a series of simulation, it is proved the simulated interdiffusion microstructuralcharacteristics and element distribution across the joining interface are in coincidence with the corresponding experimentaldata. The thermally activated IMC evolution in diffusion bonding is in thermodynamic equilibrium, while accelerated IMCevolution in friction stir welding results from thermomechanically activated D and M. The present study contributes to theunderstanding of interfacial microstructures evolution in solid state joining of dissimilar alloys.
Yuan Zihan,Zhao Haizhou,Zhi Qiaoming,Wang Sentai,Liu Chao,Han Ye,Xu Zhihua,Liu Fei,Liu Xingyi,Zan Xinquan,Wang Qiang,Wan Daiwei 한국유전학회 2022 Genes & Genomics Vol.44 No.12
Background: It has been well established that the long non-coding RNAs (lncRNAs) plays a critical role in tumor progression. However, the function of these transcripts and mechanisms responsible for their deregulation in colorectal cancer (CRC) remain to be investigated. Objective: To explore the potential effect and regulation mechanism of lncRNA H19X in colorectal cancer. Methods: We predicted and validated long non-coding RNA H19X from microarray data of colorectal cancer tissues. In addition, the biological behaviors of H19X and miR-503-5p on CRC were examined in vitro and in vivo, including MTT, colony formation assay, Hoechst33342 and transwell assay. The mRNA and protein levels of KN Motif and Ankyrin Repeat Domains 1 (KANK1) were analyzed by Quantitative real-time PCR (qRT-PCR), western blotting (WB) assay. Moreover, bioinformatics tools and dual-luciferase reporter assay were applied to demonstrate the relationship between KANK1 and miR-503-5p. Results: H19X was remarkably up-regulated in CRC tissues. Its expression related to tumor size (p = 0.041), lymph node metastasis (p = 0.037), distal metastasis (p = 0.028), advanced TNM stage (p = 0.034) and poor survival in CRC. H19X acted as an oncogenic lncRNA that induced CRC cell proliferation, invasion and metastasis. Through a number of functional studies, we found that H19X silencing inhibited the malignance phenotype of cancer cells through loss of miR-503-5p. Further studies demonstrated that miR-503-5p was involved in the progression of CRC by directly regulating the downstream target KANK1. Conclusion: Collectively, the findings of the present study indicate H19X/miR-503-5p/KANK1 axis has critical role in the progression of colorectal cancer, providing an effective prognostic indicator and promising target in treatment of colorectal cancer.
Rui Huang,Xinquan Zhang,Boon Ping Ng,A. Senthil Kumar,Kui Liu 한국정밀공학회 2021 International Journal of Precision Engineering and Vol.8 No.1
Fresnel-based concentrated photovoltaic (CPV) solar power systems have been proven effective to significantly enhance the photoelectric conversion efficiency, but a standard-size solar plant will require an extremely large amount of polymer radial Fresnel lenses. Roll-to-roll (R2R) manufacturing is a high-throughput technology to mass produce high-quality functional optical polymer fi lm. In this paper, we have firstly studied a complete manufacturing cycle for R2R embossing of radial Fresnel lens polymer fi lm for CPV systems, in terms of polymer lens design, roller mold machining, R2R embossing and optical performance test. Instead of wrapping an electroplated metal sheet onto the roller in conventional R2R process, the lens pattern array is directly machined using a 5-axis ultra-precision machining system to guarantee its surface quality and accuracy. Optical performance evaluation for the manufactured polymer fi lm using a reference solar cell is conducted, and results have shown that radial Fresnel lens on the polymer fi lm can achieve a sunlight concentration ratio 3.9 × times that of linear lenses with a much smaller receiving area. This study has explored the feasibility for R2R embossing of optical polymer fi lm, an industry-applicable and cost-effective technology for mass production of high-quality Fresnel lenses to be used in high-efficiency CPV systems.
An Overview of Whipgrass Breeding Efforts in Sichuan Agricultural University
Yang Chunhua,Zhang Xinquan,Cheng Lingzhi,Liu Lin,Tang Zhisong 한국초지조사료학회 2009 한국초지조사료학회 학술대회논문집 Vol.2009 No.08
Whipgrass [Hemarthriacompressa(Linn.f.)R.Br.] has several outstanding characteristics that make it attractive in livestock production systems. These include superior cool-season growth compared to other C₄ grasses, persistence under grazing on poorly drained soils, and relatively high herbage digestibility that declines at a slower rate with increasing maturity than for most C₄ grasses. More than 50 years hard work, a whipgrass breeding group in Sichuan Agricultural University (SAU) collected 84 accessions from south china. Through germplasm evaluation and breeding, 3 varieties, Chong gao, Guang yi and Ya an, were released by the end of 2009. All of them are very popular in south china from 1986. In the future, the team approach emphasizes plant improvement in seedling vigor and establishment, seed production, cold tolerance, photoperiod response, seasonal distribution of forage production, forage quality, insect and disease resistance.