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RISS 인기검색어
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- 저자 : Xingchen Zhou (검색결과 4 건)
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Xingchen Zhou,Husheng Wang,Xipeng Wang 대한부인종양학회 2017 Journal of Gynecologic Oncology Vol.28 No.2
Objective: The aim of this study was to build a model to predict the risk of lymphovascular space invasion (LVSI) in women with endometrial cancer (EC). Methods: From December 2010 to June 2013, 211 patients with EC undergoing surgery at Shanghai First Maternity and Infant Hospital were enrolled in this retrospective study. Those patients were divided into a positive LVSI group and a negative LVSI group. The clinical and pathological characteristics were compared between the two groups; logistic regression was used to explore risk factors associated with LVSI occurrence. The threshold values of significant factors were calculated to build a risk model and predict LVSI. Results: There were 190 patients who were negative for LVSI and 21 patients were positive for LVSI out of 211 patients with EC. It was found that tumor grade, depth of myometrial invasion, number of pelvic lymph nodes, and International Federation of Gynecology and Obstetrics (FIGO) stage (p<0.05) were associated with LVSI occurrence. However, cervical involvement and age (p>0.05) were not associated with LVSI. Receiver operating characteristic (ROC) curves revealed that the threshold values of the following factors were correlated with positive LVSI: 28.1 U/mL of CA19-9, 21.2 U/mL of CA125, 2.58 mg/dL of fibrinogen (Fn), 1.84 U/mL of carcinoembryonic antigen (CEA) and (6.35×109)/L of white blood cell (WBC). Logistic regression analysis indicated that CA125 ≥21.2 (p=0.032) and Fn ≥2.58 mg/dL (p=0.014) were significantly associated with LVSI. Conclusion: Positive LVSI could be predicted by CA125 ≥21.2 U/mL and Fn ≥2.58 mg/dL in women with EC. It could help gynecologists better adapt surgical staging and adjuvant therapies.
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Xingchen Li,Yiqin Wang,Jiaqi Wang,Jingyi Zhou,Jianliu Wang 대한부인종양학회 2024 Journal of Gynecologic Oncology Vol.35 No.4
Objective: This study aims to assess the impact of the metabolic risk score (MRS) on timeto achieve complete remission (CR) of fertility-sparing treatments for atypical endometrialhyperplasia (AEH) and early endometrial cancer (EC) patients. Methods: Univariate and multivariate cox analyses were employed to identif y independentrisk factors affecting the time to CR with patients at our center. These factors weresubsequently incorporated into receiver operator characteristic cur ve analysis and decisioncur ve analysis to assess the predictive accuracy of time to CR. Additionally, Kaplan–Meieranalysis was utilized to determine the cumulative CR rate for patients. Results: The 173 patients who achieved CR following fertility preser vation treatment (FPT)were categorized into three subgroups based on their time to CR (<6, 6–9, >9 months). Bodymass index (hazard ratio [HR]=0.20; 95% confidence inter val [CI]=0.03, 0.38; p=0.026),MRS (HR=0.31; 95% CI=0.09, 0.52; p=0.005), insulin resistance (HR=1.83; 95% CI=0.05,3.60; p=0.045), menstruation regularity (HR=3.77; 95% CI=1.91, 5.64; p=0.001), polycysticovar y syndrome (HR=−2.16; 95% CI=−4.03, −0.28; p=0.025), and histological type (HR=0.36;95% CI=0.10, 0.62; p=0.005) were identified as risk factors for time to CR, with MRSbeing the independent risk factor (HR=0.29; 95% CI=0.02, 0.56; p=0.021). The inclusionof MRS significantly enhanced the predictive accuracy of time to CR (area under the cur ve[AUC]=0.789 for Model 1, AUC=0.862 for Model 2, p=0.032). Kaplan–Meier sur vival cur vesrevealed significant differences in the cumulative CR rate among different risk groups. Conclusion: MRS emerges as a novel evaluation system that substantially enhances thepredictive accuracy for the time to achieve CR in AEH and early EC patients seeking fertilitypreser vation.
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Experimental and numerical investigation on exposed RCFST column-base Joint
Ben Mou,Xingchen Yan,Qiyun Qiao,Wanqiu Zhou 국제구조공학회 2022 Steel and Composite Structures, An International J Vol.45 No.5
This paper investigates the seismic performance of exposed RCFST column-base joints, in which the high-strength steel bars (USD 685) are set through the column and reinforced concrete foundation without any base plate and anchor bolts. Three specimens with different axial force ratios (n = 0, 0.25, and 0.5) were tested under cyclic loadings. Finite element analysis (FEA) models were validated in the basic indexes and failure mode. The hysteresis behavior of the exposed RCFST columnbase joints was studied by the parametrical analysis including six parameters: width of column (D), width-thickness ratio (D/t), axial force ratio (n), shear-span ratio (L/D), steel tube strength (fy) and concrete strength (fc). The bending moment of the exposed RCFST column-base joint increased with D, fy and fc. But the D/t and L/D play a little effect on the bending capacity of the new column-base joint. Finally, the calculation formula is proposed to assess the bending moment capacities, and the accuracy and stability of the formula are verified.
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Ce3+ triggers fenton-like processes in neutral solutions for effective catechol degradation
Xing Chen,Xu Liu,Hai-Bo Wang,Kang-Ping Cui,Rohan Weerasooriya,Shi-Long He,Guang-Hong Li,Jun Pan,Kai Zhou 대한환경공학회 2022 Environmental Engineering Research Vol.27 No.1
Classical Fenton and Fenton-like processes destruct organic pollutants in water non-selectively to complete mineralization. However, the usage of classical Fenton or Fenton-like processes is often limited due to the narrow operational pH window, sludge accumulation, inefficient H₂O₂ and efficiency decline. To overcome these constraints, in this study, we used a homogeneous Fe<SUP>3+</SUP>-Ce<SUP>3+</SUP>-H₂O₂ Fenton-like process to degrade catechol at different experimental conditions. At pH 7, almost 97% of 10 mM catechol can be destructed within 60 min while the degradation by Classical Fenton or Fe<SUP>3+</SUP>-H₂O₂ Fenton-like process only 36.2% and 23.7%. The resultant solution after the degradation contains only traces of cerium ions. The sludge created by the process was extensively characterized by FTIR and XPS spectroscopy to elucidate the fate of cerium ions. Electron spin resonance (ESR) data confirmed •OH as the major free radical in Fe<SUP>3+</SUP>-Ce<SUP>3+</SUP>-H₂O₂ process. Our Fenton-like process widens the optimal pH values to neutral condition.
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