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      • A Sense Embedding of Deep Convolutional Neural Networks for Sentiment Classification

        Zhijian Cui,Xiaodong Shi,Yidong Chen,Yinmei Guo 보안공학연구지원센터 2016 International Journal of Grid and Distributed Comp Vol.9 No.11

        Sentiment classification task has attracted considerable interest as sentiment information is crucial for many natural language processing (NLP) applications. The goal of sentiment classification is to predict the overall emotional polarity of a given text. Previous work has demonstrate the remarkable performance of Convolutional Neural Network (CNN). However, nearly all this work assumes a single word embedding for each word type, ignoring polysemy and thus inevitably casting negative impact on the downstream tasks. We extend the Skip-gram model to learn multiple sense embeddings for the word types, catering to introduce sense-based embeddings for CNN during sentiment classification. Instead of using the pipeline method to learn multiple sense embeddings of a word type, the sense discrimination and sense embedding learning for each word type are performed jointly based upon the semantics of its contextual words. We validate the effectiveness of the method on the commonly used datasets. Experiment results show that our method are able to improve the quality of sentiment classification when comparing with several competitive baselines.

      • KCI등재

        Protective Effect of Astragaloside IV against Matrix Metalloproteinase- 1 Expression in Ultraviolet-Irradiated Human Dermal Fibroblasts

        Bo Yang,Chao Ji,Xiaodong Chen,Lunbiao Cui,Zhigang Bi,Yinsheng Wan,Jinhua Xu 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.9

        Ultraviolet (UV) irradiation induces skin photoaging associated with up-regulated matrix metalloproteinase (MMP) expression. Inhibition of MMP expression is suggested to alleviate photoaging induced by UV irradiation. Astragaloside IV (As-IV), one of the main active ingredients of Astragalus membranaceus (Fisch) Bge, has been reported to have various biological activities. However, its anti-photoaging effect has not been examined to date. In the present study, we observed the effect of As-IV on matrix metalloproteinase-1 (MMP-1) expression in UV-irradiated human dermal fibroblasts (HDFs). We found that treatment with As-IV significantly decreased UV-induced MMP-1 expression at the messenger RNA and protein levels. In addition, western blotting analysis revealed that As-IV concentration-dependently suppressed UV-induced phosphorylation of extracellular-regulated protein kinase, Jun-N-terminal kinase and p38 mitogen-activated protein kinase (MAPK). Furthermore, treatment with As-IV markedly inhibited UV-induced nuclear factor kappaB (NF-κB) activity. These results suggest that As-IV down-regulates UV-induced MMP-1 expression, perhaps through suppression of MAPK and NF-κB activation in HDFs. As-IV is thus a potential agent for the management of skin photoaging.

      • KCI등재

        Sparstolonin B suppresses lipopolysaccharide-induced inflammation in human umbilical vein endothelial cells

        Qiaoli Liang,Fang Yu,Xiaodong Cui,Jin-ao Duan,Qinan Wu,Prakash Nagarkatti,Daping Fan 대한약학회 2013 Archives of Pharmacal Research Vol.36 No.7

        Sparstolonin B (SsnB) is an isocoumarin compoundisolated from the tubers of both Sparganium stoloniferumand Scirpus yagara. We previously demonstratedthat SsnB blocked the Toll-like receptor (TLR) 2- andTLR4-triggered inflammatory signaling in macrophages byinhibiting the recruitment of MyD88 to the TIR domains ofTLR2 and TLR4. The present study was designed toexamine the effects of SsnB on vascular inflammatoryresponses in human umbilical vein endothelial cells (HUVECs)challenged by lipopolysaccharide (LPS, a TLR4ligand). We found that SsnB dose-dependently attenuatedthe LPS-induced expression of interleukin (IL)-1b andmonocyte chemoattractant protein 1 both at the transcriptionand translation levels in HUVEC. LPS-inducedendothelial cell adhesion molecules, intercellular adhesionmolecular-1 and vascular cell adhesion molecule-1expressions were also reduced by treatment with SsnB. Inaddition, co-incubation with SsnB attenuated THP-1monocyte adhesion to LPS-activated HUVECs. Furthermore,SsnB efficiently suppressed LPS-induced phosphorylationof extracellular -signal-regulated kinase (Erk1/2)and Akt in HUVECs. These findings show that SsnB cansuppress endothelial cell inflammation, suggesting thatSsnB might be suitable for development as a therapeuticagent for inflammatory cardiovascular disease.

      • Numerical analysis of stress wave of projectile impact composite laminate

        Zhangxin Guo,Weijing Niu,Junjie Cui,Gin Boay Chai,Yongcun Li,Xiaodong Wu 국제구조공학회 2023 Structural Engineering and Mechanics, An Int'l Jou Vol.87 No.2

        The three-dimensional Hashin criterion and user subroutine VUMAT were used to simulate the damage in the composite layer, and the secondary stress criterion was used to simulate the interlayer failure of the cohesive element of the bonding layer and the propagation characteristics under the layer. The results showed that when the shear stress wave (shear wave) propagates on the surface of the laminate, the stress wave attenuation along the fiber strength direction is small, and thus producing a large stress profile. When the compressive stress wave (longitudinal wave) is transmitted between the layers, it is reflected immediately instead of being transmitted immediately. This phenomenon occurs only when the energy has accumulated to a certain degree between the layers. The transmission of longitudinal waves is related to the thickness and the layer orientation. Along the symmetry across the thickness direction, the greater is the stress amplitude along the layer direction. Based on the detailed investigation on the impact on various laminated composites carried out in this paper, the propagation characteristics of stress waves, the damage and the destruction of laminates can be explained from the perspective of stress waves and a reasonable layering sequence of the composite can be designed against damage and failure from low velocity impact.

      • KCI등재

        Raman scattering investigations on Co-doped ZnO epitaxial films: Local vibration modes and defect associated ferromagnetism

        Qiang Cao,Shumin He,Yuanyuan Deng,Dapeng Zhu,Xiaodong Cui,Guolei Liu,Huai-Jin Zhang,Shishen Yan,Yanxue Chen,Liangmo Mei 한국물리학회 2014 Current Applied Physics Vol.14 No.5

        Raman scattering spectroscopy has been performed on high quality Co-doped ZnO epitaxial films, which were grown on Al2O3 (0001) by oxygen-plasma assisted molecular beam epitaxy. Raman measurements revealed two local vibration modes (LVMs) at 723 and 699 cm1 due to the substitution of Co2þ in wurtzite ZnO lattice. The LVM at 723 cm1 is found to be an elemental sensitive vibration mode for Co substitution. The LVM at 699 cm1 can be attributed to enrichment of Co2þ bound with oxygen vacancy, the cobalteoxygen vacancyecobalt complexes, in Zn1xCoxO films associated with ferromagnetism. The intensity of LVM at 699 cm1, as well as saturated magnetization, enhanced after the vacuum annealing and depressed after oxygen annealing.

      • Stabilization of Hexaaminobenzene in a 2D Conductive Metal-Organic Framework for High Power Sodium Storage

        Park, Jihye,Lee, Minah,Feng, Dawei,Huang, Zhehao,Hinckley, Allison C.,Yakovenko, Andrey,Zou, Xiaodong,Cui, Yi,Bao, Zhenan American Chemical Society 2018 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.140 No.32

        <P>Redox-active organic materials have gained growing attention as electrodes of rechargeable batteries. However, their key limitations are the low electronic conductivity and limited chemical and structural stability under redox conditions. Herein, we report a new cobalt-based 2D conductive metal-organic framework (MOF), Co-HAB, having stable, accessible, dense active sites for high-power energy storage device through conjugative coordination between a redox-active linker, hexaaminobenzene (HAB), and a Co(II) center. Given the exceptional capability of Co-HAB for stabilizing reactive HAB, a reversible three-electron redox reaction per HAB was successfully demonstrated for the first time, thereby presenting a promising new electrode material for sodium-ion storage. Specifically, through synthetic tunability of Co-HAB, the bulk electrical conductivity of 1.57 S cm<SUP>-1</SUP> was achieved, enabling an extremely high rate capability, delivering 214 mAh g<SUP>-1</SUP> within 7 min or 152 mAh g<SUP>-1</SUP> in 45 s. Meanwhile, an almost linear increase of the areal capacity upon increasing active mass loading up to 9.6 mg cm<SUP>-2</SUP> was obtained, demonstrating 2.6 mAh cm<SUP>-2</SUP> with a trace amount of conducting agent.</P> [FIG OMISSION]</BR>

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