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- 저자 : Weilun Wang (검색결과 4 건)
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Weilun Wang,Junting Li,Wenjun Peng 한양대학교 세라믹연구소 2019 Journal of Ceramic Processing Research Vol.20 No.S1
This study used a temperature stress test machine (TSTM) to study the effects of the water-to-cement (w/c) ratio, curingmethod and the content of polyvinyl alcohol (PVA) fiber on the autogenous shrinkage of high-performance concrete (HPC). The experimental values were compared with theoretical values obtained from four sets of autogenous shrinkage models tocompare model accuracy. The study results indicated the followings: (1) the autogenous shrinkage value of concrete increasedwith decreases in the w/c ratio. (2) The natural and semi-adiabatic curing conditions caused the specimens to form a low- anda high-temperature rise, respectively. The higher the temperature rise, the larger the stable value of the autogenous shrinkage. (3) Among the CEB-FIP, EN-1992, RILEM and Tazawa models, the Tazawa model demonstrated the highest degree ofaccuracy. (4) PVA fiber contents of 0.75% and 0.25% had the most significant and minimal autogenous shrinkages,respectively.
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Effect of lead sulfate on chloride ion transport properties in cementitious material
Xianfeng Wang,Yabin Yuan,Yingxin Huang,Tielin Han,Weilun Wang,Jian Liu,Feng Xing 한양대학교 세라믹연구소 2019 Journal of Ceramic Processing Research Vol.20 No.S1
A novel microcapsule-based self-healing system was developed in Guangdong Key Laboratory of Durability in Coastal CivilEngineering to prolong the concrete service life, in which lead sulfate is used as the shell material of the microcapsules. Theself-healing system is triggered by the reaction of lead sulfate with chloride ion. In this study, the effect of lead sulfate onchloride ion transport in cement-based materials was investigated. The bulk diffusion and rapid chloride migration tests werecarried out. The time dependence of chloride diffusion was analysed based on the results of the Bulk diffusion test. The changein the microstructure of cement-based materials upon incorporation of lead sulfate was observed and analysed via mercuryintrusion porosimetry and scanning electron microscopy. Results showed that chloride-binding was prevalent at an immersionperiod of less than 90 days, while sulfate attack superseded after 90 days. Therefore, the impact of both factors needs to beconsidered when utilizing lead sulfate as a shell material in cementitious materials.
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Zhou Weilun,Wu Cuiping,Wang Jiao 대한독성 유전단백체 학회 2023 Molecular & cellular toxicology Vol.19 No.3
Background Emerging evidence has revealed that circular RNAs (circRNAs) are critical regulators for the development of various tumors, containing diff use large B-cell lymphoma (DLBCL). CircRNA microarray analysis suggested that circ_0000877 was freakishly increased in DLBCL tissues. Objective This study is designed to explore the role and mechanism of circ_0000877 on DLBCL development. Results Circ_0000877 and HK2 were increased, and miR-671-5p was reduced in DLBCL tissues and cell lines. Also, circ_0000877 silencing hindered DLBCL cell proliferation and glycolysis, and induced apoptosis in vitro. Mechanically, circ_0000877 functioned as a sponge of miR-671-5p, and circ_0000877 knockdown-mediated DLBCL cell development inhibition was relieved by miR-671-5p downregulation. Moreover, HK2 acted as a direct target gene of miR-671-5p, and enhanced HK2 might abolish the impact of miR-671-5p on DLBCL cell progression. Conclusion Circ_0000877 silencing mitigated DLBCL cell malignant biological behavior partly via miR-671-5p/HK2 axis, referring to circ_0000877 as an underlying prognostic biomarker. These data provided a promising strategy for treating DLBCL malignancies.
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Long Yan,Ying Yu,Kaijiang Kang,Zhikai Hou,Min Wan,Weilun Fu,Rongrong Cui,Yongjun Wang,Zhongrong Miao,Xin Lou,Ning Ma 대한신경과학회 2022 Journal of Clinical Neurology Vol.18 No.5
Background and Purpose Intracranial vertebrobasilar atherosclerotic stenosis (IVBAS) is a major cause of posterior circulation stroke. Some patients suffer from stroke recurrence despite receiving medical treatment. This study aimed to determine the prognostic value of a new score for the posterior communicating artery and the P1 segment of the posterior cerebral artery (PCoA-P1) for predicting stroke recurrence in IVBAS. Methods We retrospectively enrolled patients with severe IVBAS (70%–99%). According to the number of stroke recurrences, patients were divided into no-recurrence, single-recurrence, and multiple-recurrences groups. We developed a new 5-point grading scale, with the PCoA-P1 score ranging from 0 to 4 based on magnetic resonance angiography, in which primary collaterals were dichotomized into good (2–4 points) and poor (0 or 1 point). Stroke recurrences after the index stroke were recorded. Patients who did not experience stroke recurrence were compared with those who experienced single or multiple stroke recurrences. Results From January 2012 to December 2019, 176 patients were enrolled, of which 116 (65.9%) had no stroke recurrence, 35 (19.9%) had a single stroke recurrence, and 25 (14.2%) had multiple stroke recurrences. Patients with single stroke recurrence (odds ratio [OR]= 4.134, 95% confidence interval [CI]=1.822–9.380, p=0.001) and multiple stroke recurrences (OR=6.894, 95% CI=2.489–19.092, p<0.001) were more likely to have poor primary collaterals than those with no stroke recurrence. Conclusions The new PCoA-P1 score appears to provide improve predictions of stroke recurrence in patients with IVBAS
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