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Potential strategies for prevention of tumor spillage in minimally invasive radical hysterectomy
Vicente Bebia,Sonia Monreal-Clua,Assumpció Pérez-Benavente,Silvia Franco-Camps,Berta Díaz-Feijoo,Antonio Gil-Moreno 대한부인종양학회 2020 Journal of Gynecologic Oncology Vol.31 No.5
Objective: The publication of a prospective [1] and several retrospective [2,3] studiesdescribing a worse prognosis in patients affected with early-stage cervical cancer whounderwent a minimally invasive radical hysterectomy has raised a high concern in whatmeasures should be undertaken in order to revert these results. Potential strategies [4] toprevent tumor spillage have been previously proposed. Methods: In this video, we describe nine strategies that should be addressed in future trialsregarding this procedure. Results: These strategies are:1. Fallopian tubes should be coagulated prior to start the surgery. 2. All sentinel lymph nodes and lymphadenectomy specimens should be obtained withoutlymph nodes fragmentation. 3. All surgical specimens should be extracted within a containment bag. 4. Uterine manipulators must never be used. 5. Prior to vaginal section, a closed knotted ligature should be placed around the vagina,proximal to the section line, and the remaining vaginal cavity profusely washed. 6. Once the vagina is opened, the surgical specimen should be extracted vaginally within aspecimen retrieval bag. 7. After surgery, the pelvic cavity is profusely washed with physiological serum, and the vaginashould be washed with iodopovidone diluted to 10% [5]. 8. Port-site metastasis prevention measures should be performed. 9. Every action made to prevent tumor spillage should be recorded in the surgical report. Conclusion: As there is a biological rationale in these measures that would prevent tumorspillage and seeding, there is a need of prospectively exploring them within appropriatestudies in order to determine their own oncological outcome.
Sideslip angle estimator based on ANFIS for vehicle handling and stability
Beatriz L. Boada,María Jesús L. Boada,Antonio Gauchía,Ester Olmeda,Vicente Díaz 대한기계학회 2015 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.29 No.4
Most of the existing ESC (Electronic stability control) systems rely on the measurement of both yaw rate and sideslip angle. However,one of the main issues is that the sideslip angle cannot be measured directly because the sensors are too expensive. For this reason, sideslipangle estimation has been widely discussed in literature. The modeling of sideslip angle is complex due to the non-linear dynamics ofthe vehicle. This work proposes a new methodology based on ANFIS to estimate the vehicle sideslip angle. The estimator has been validatedby comparing the proposed ANFIS prediction model with the values provided by CARSIM model, which is an experimentallyvalidated software. The advantage of this estimation is the modeling of the non-linear dynamics of the vehicle by means of signals whichare directly measured from vehicle sensors. The results show the effectiveness of the proposed ANFIS-based sideslip angle estimator.