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      • KCI등재

        Facile synthesis of boron and nitrogen doped TiO2 as effective catalysts for photocatalytic degradation of emerging micro-pollutants

        Vandana Yadav,Himani Sharma,Amit Rana,Vipin K. Saini 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.107 No.-

        The development of photocatalysts for efficient photodegradation of emerging water pollutants is a subjectof global concern in recent years. In this study, the photophysical properties of TiO2 were modified bydoping with different concentrations of boron (B-TiO2) and nitrogen (N-TiO2) by following a sol–gel routeof synthesis. The type and concentration of dopants were optimized to achieve maximum degradation ofacetaminophen (ACT) and monocrotophos (MCP) in aqueous solutions. UV DRS analysis shows that thebandgap of TiO2 (3.2 eV) reduced up to 2.96 and 2.27 eV in B-TiO2 and N-TiO2 samples, respectively. The presence of dopants inside the crystal lattice of doped TiO2 was confirmed with X-ray diffraction(XRD), Micro Raman, Fourier Transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy(XPS). The XRD data confirmed that the presence of these dopants promotes the rutile phasetransformation in TiO2 to various extents. The doping of B decreased the surface area and pore volumeof TiO2, whereas N doping had increased these properties. The XPS spectra showed the formation ofTi-O-B and Ti-O-N type linkage, indicating the presence of interstitial B and substitutional N atoms inTiO2 crystal lattice. The B doped samples exhibit more enhancement in photodegradation efficiency ascompared to N doped samples. Under optimized conditions, 5% B-TiO2 showed 95% and 71% degradationof ACT and MCP, respectively. The degradation pathway for both ACT and MCP involving their intermediateswas discussed through Mass spectrometry analysis. The cost-effectiveness of the most efficientdoped catalysts and commercial catalysts were compared with the ACER tool and turnover frequency.

      • KCI등재

        Scientific exploration on physiological basis of Svedana Karma (Sudation): A clinical application of heat stress.

        Yadav, Saurabh,Verma, Vandana,Abhinav, Abhinav Cellmed Orthocellular Medicine and Pharmaceutical 2019 셀메드 (CellMed) Vol.9 No.3

        Now researchers have focused attention on exploring the mechanism of acute responses of heat stress given in heat therapy that ultimately promotes the long term health benefits. Heat therapy is not a new idea rather it was practiced since thousands years back in the form of hot bath, sauna bath, steam room. Similarly in Ayurveda there is very comprehensive description of heat therapy in the form of Svedan karma (Sudation therapy). Svedan is a process to induce sweating artificially in a patient who had already undergone Snehan. Svedan is applied for purification of body, as well as in management of various disorders originated due to vitiation of Vata, Kapha Dosha, Meda Dhatu and musculoskeletal disorders. It produces various beneficial effects by augmenting the Agni like clears the channels, liquefies the deposited Dosha, regulates Vata Dosha, helps in removal and pacification of Dosha, augments metabolism (Agni Deepan), increases appetite, flexibility in body parts, softness and shining of skin, removes coldness, stiffness, drowsiness, improves joint motility. However, Svedana karma is vastly used by Ayurveda Physicians in treatment of various disorders but the mechanisms of beneficial effects produced by Svedan Karma are yet not completely explored on scientific basis. In this article, we will discuss and try to establish a possible mechanism of action of Svedana karma in relation to heat stress, mitochondrial adaptation, heat shock protein (HSP) and glucocorticoids as these are secreted under stressful conditions.

      • KCI등재

        Peste des petits ruminants virus detected in tissues from an Asiatic lion (Panthera leo persica) belongs to Asian lineage IV

        Vinayagamurthy Balamurugan,Arnab Sen,Gnanavel Venkatesan,Vandana Bhanot,Vineeta Yadav,Veerakyathappa Bhanuprakash,Raj Kumar Singh 대한수의학회 2012 JOURNAL OF VETERINARY SCIENCE Vol.13 No.2

        In this study, peste des petits ruminants virus (PPRV) was detected in frozen pooled tissue samples from a dead Asiatic lion (Panthera leo persica). The samples were negative for canine distemper virus and positive for PPRV nucleic acids when tested with one-step RT-PCR using the appropriate virus-specific primers. Subsequent amplification, cloning, and sequencing of the partial nucleocapsid, matrix, and fusion genes confirmed the presence of PPRV nucleic acid. Comparative sequence and phylogenetic analyses of the structural genes of the isolated virus confirmed that the virus belonged to Asian lineage IV and was closely related to PPRV circulating in India.

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        Quantitative histology-based classification system for assessment of the intestinal mucosal histological changes in patients with celiac disease

        Prasenjit Das,Gaurav PS Gahlot,Alka Singh,Vandana Baloda,Ramakant Rawat,Anil K Verma,Gaurav Khanna,Maitrayee Roy,Archana George,Ashok Singh,Aasma Nalwa,Prashant Ramteke,Rajni Yadav,Vineet Ahuja,Vishnu 대한장연구학회 2019 Intestinal Research Vol.17 No.3

        Background/Aims: The existing histological classifications for the interpretation of small intestinal biopsies are based on qualitative parameters with high intraobserver and interobserver variations. We have developed and propose a quantitative histological classification system for the assessment of intestinal mucosal biopsies. Methods: We performed a computer-assisted quantitative histological assessment of digital images of duodenal biopsies from 137 controls and 124 patients with celiac disease (CeD) (derivation cohort). From the receiver-operating curve analysis, followed by multivariate and logistic regression analyses, we identified parameters for differentiating control biopsies from those of the patients with CeD. We repeated the quantitative histological analysis in a validation cohort (105 controls and 120 patients with CeD). On the basis of the results, we propose a quantitative histological classification system. The new classification was compared with the existing histological classifications for interobserver and intraobserver agreements by a group of qualified pathologists. Results: Among the histological parameters, intraepithelial lymphocyte count of ≥25/100 epithelial cells, adjusted villous height fold change of ≤0.7, and crypt depth-to-villous height ratio of ≥0.5 showed good discriminative power between the mucosal biopsies from the patients with CeD and those from the controls, with 90.3% sensitivity, 93.5% specificity, and 96.2% area under the curve. Among the existing histological classifications, our quantitative histological classification showed the highest intraobserver (69.7%–85.03%) and interobserver (24.6%–71.5%) agreements. Conclusions: Quantitative assessment increases the reliability of the histological assessment of mucosal biopsies in patients with CeD. Such a classification system may be used for clinical trials in patients with CeD.

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