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- 검색키워드
- 저자 : Tomic, Ivan Z. (검색결과 6 건)
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Seborrheic Dermatitis Is Related to Motor Symptoms in Parkinson’s Disease
Svetlana Tomic,Igor Kuric,Tihana Gilman Kuric,Zvonimir Popovic,Jagoda Kragujevic,Tea Mirosevic Zubonja,Ines Rajkovaca,Sara Matosa 대한신경과학회 2022 Journal of Clinical Neurology Vol.18 No.6
Background and Purpose Parkinson’s disease (PD) patients present with numerous motor and nonmotor symptoms. Seborrheic dermatitis (SD) is reported in 18.6%–59% of PD patients. However, the etiology of SD in PD patients remains unknown. The aim of this study was to determine how motor and nonmotor symptoms, age, sex, and levodopa-equivalent daily dose (LEDD) influence the appearance and severity of SD in PD patients, and then discuss about SD possible etiology based on the obtained results. Methods Motor symptoms were evaluated using the Unified Parkinson’s Disease Rating Scale part III and nonmotor symptoms were evaluated using the Parkinson’s Disease Sleep Scale, Scales for Outcomes in Parkinson’s Disease–Autonomic Dysfunction, and Non-Motor Symptoms Questionnaire. LEDD was calculated and demographic data on age, sex, disease duration, and symptoms of SD prior to a PD diagnosis were collected. A dermatologist evaluated the skin for SD using the Seborrhea Area and Severity Index. Results SD was present in 36.1% of the PD patients. There were positive correlations between age, motor-symptoms severity, and SD. After adjusting for age, disease duration, and sex, there remained a positive correlation between the severity of motor symptoms and SD. Patients with moderate-to-severe motor symptoms had more-severe SD symptoms, and their risk of developing SD was 1.8-fold higher. There was no correlation between SD and autonomic dysfunction, sleep disturbances, or other nonmotor symptoms, and no sex difference. Conclusions In PD, SD is related to motor symptoms.
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Eversion Carotid Endarterectomy : A Short Review
Davidovic, Lazar B.,Tomic, Ivan Z. The Korean Neurosurgical Society 2020 Journal of Korean neurosurgical society Vol.63 No.3
Carotid endarterectomy (CEA) is the main procedure in carotid surgery, as well as the most frequent vascular procedure. Two techniques of CEA are available : eversion and conventional plus patch angioplasty. Eversion CEA is anatomic procedure that reduces ischemic and total operative time. Simultaneous correction of the joined carotid kinking and coiling is possible, easy and safe, while the usage of patch is excluded. Thanks to oblique shape of anastomosis, eversion CEA is associated with low risk of long-term restenosis. The false anastomotic aneurysms occurrence is very rare, almost impossible after eversion CEA. However, the usage of carotid shunt during eversion CEA is not always simple, while proximal or distal extension of the carotid plaque can make eversion CEA more difficult and risky. Eversion CEA should be the first choice in carotid surgery. Conventional CEA is indicated in cases when carotid plaque is extended more than usual, as well as, if the usage of carotid shunt is necessary.
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Global hydroelastic analysis of ultra large container ships by improved beam structural model
Senjanovic, Ivo,Vladimir, Nikola,Tomic, Marko,Hadzic, Neven,Malenica, Sime The Society of Naval Architects of Korea 2014 International Journal of Naval Architecture and Oc Vol.6 No.4
Some results on the hydroelasticity of ultra large container ships related to the beam structural model and restoring stiffness achieved within EU FP7 Project TULCS are summarized. An advanced thin-walled girder theory based on the modified Timoshenko beam theory for flexural vibrations with analogical extension to the torsional problem, is used for formulation of the beam finite element for analysis of coupled horizontal and torsional ship hull vibrations. Special attention is paid to the contribution of transverse bulkheads to the open hull stiffness, as well as to the reduced stiffness of the relatively short engine room structure. In addition two definitions of the restoring stiffness are considered: consistent one, which includes hydrostatic and gravity properties, and unified one with geometric stiffness as structural contribution via calm water stress field. Both formulations are worked out by employing the finite element concept. Complete hydroelastic response of a ULCS is performed by coupling 1D structural model and 3D hydrodynamic model as well as for 3D structural and 3D hydrodynamic model. Also, fatigue of structural elements exposed to high stress concentration is considered.
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Investigation of torsion, warping and distortion of large container ships
Senjanovic, Ivo,Vladimir, Nikola,Tomic, Marko Techno-Press 2011 Ocean systems engineering Vol.1 No.1
Large deck openings of ultra large container ships reduce their torsional stiffness considerably and hydroelastic analysis for reliable structural design becomes an imperative. In the early design stage the beam model coupled with 3D hydrodynamic model is a rational choice. The modal superposition method is ordinary used for solving this complex problem. The advanced thin-walled girder theory, with shear influence on both bending and torsion, is applied for calculation of dry natural modes. It is shown that relatively short engine room structure of large container ships behaves as the open hold structure with increased torsional stiffness due to deck effect. Warping discontinuity at the joint of the closed and open segments is compensated by induced distortion. The effective torsional stiffness parameters based on an energy balance approach are determined. Estimation of distortion of transverse bulkheads, as a result of torsion and warping, is given. The procedure is illustrated in the case of a ship-like pontoon and checked by 3D FEM analysis. The obtained results encourage incorporation of the modified beam model of the short engine room structure in general beam model of ship hull for the need of hydroelastic analysis, where only the first few natural modes are of interest.
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Nikola Kresojević,Ivana Perović,Iva Stankovic,Aleksandra Tomic,Milica Jecmenica Lukic,Vladana Markovic,Tanja Stojkovic,Gorana Mandic,Milena Jankovic,Ana Marjanovic,Marija Brankovic,Ivana Novakovic,Igo 대한파킨슨병및이상운동질환학회 2023 Journal Of Movement Disorders Vol.16 No.3
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease caused by an expansion of CAG trinucleotide repeats in the HTT gene, which encodes the huntingtin protein
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Ana Krkobabić,Darka Marković,Aleksandar Kovačević,Vanja Tadić,Marija Radoičić,Tatjana Barudžija,Tatjana Ilic-Tomic,Maja Radetić 한국섬유공학회 2022 Fibers and polymers Vol.23 No.4
The aim of this study was to develop antimicrobial nanocomposite textile material comprising of Cu-basednanostructures synthesized on oxidized cotton fabric using Arctostaphylos uva-ursi (L.) Spreng., Ericaceae (bearberry leaves)as a green reducing agent for adsorbed Cu2+-ions. In order to provide sufficient number of carboxyl groups for complexationwith Cu2+-ions a two-step oxidation process with NaIO4 and NaClO2 was carried out. The influence of NaIO4 concentrationon content of carboxyl groups and Cu-based nanoparticles was studied by FTIR and AAS. HPLC analysis identified thegallic acid known as a reducing agent in bearberry leaves extract. FESEM and XRD analyses revealed that using bearberryleaves extract and gallic acid solution as reducing agents led to a formation of spherical Cu2O/CuO nanoparticles and CuOnanosheets, respectively. These nanoparticles and nanosheets provided excellent antibacterial activity against Gram-negativebacteria Escherichia coli and Gram-positive bacteria Staphylococcus aureus. Cytotoxicity on human keratinocyte cells wasshown to depend on their copper content.
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