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        ASEAN+3: C/community building in East Asia?

        Nick Thomas 서울대학교 국제학연구소 2001 Journal of International and Area Studies Vol.8 No.2

          This article analyses the impact ASEAN’s expansion to include the+3 countries of China, Japan and South Korea. By placing post-97 developments in a chronological and sectoral matrix, this article attempts to evaluate ASEAN’s recent efforts at region-building. It is argued that the expansion of ASEAN’s Informal membership coupled with a higher level of policy convergence by ASEAN member countries at the regional and sub-regional levels is leading towards the development of an East Asian bloc. The choice now confronting these countries is whether to institutionalize the current arrangements or to allow the present, looser formation to continue.

      • KCI등재

        ASEAN+3: C/community building in East Asia?

        Thomas, Nick 서울대학교 국제지역원 2001 Journal of International and Area Studies Vol.8 No.2

        This article analysed the impact ASEAN's expansion to include the +3 countries of China, Japan and South Korea. By placing post-97 developments in a chronological and sectoral matrix, this article attempts to evaluate ASEAN's recent efforts at region-building. It is argued that the expansion of ASEAN's Informal membership coupled with a higher level of policy convergence by ASEAN member countries at the regional and sub-regional levels is leading towards the development of an East Asian bloc. The choice now confronting these countries is whether to institutionalize the current arrangements or to allow the present, looser formation to continue.

      • KCI등재

        Pituitary apoplexy in an adolescent male with macroprolactinoma presenting as middle cerebral artery territory infarction

        Agrawal Pankaj,Newbold Sally,Busaidi Ayisha Al,Kapoor Ritika R,Thomas Nick,Aylwin Simon JB,Buchanan Charles R,Arya Ved Bhushan 대한소아내분비학회 2022 Apem Vol.27 No.4

        Pituitary apoplexy typically presents with acute headache, vomiting, visual disturbance, and confusion. Herein, we report a rare presentation of ischemic stroke due to pituitary apoplexy. A 16.5-year-old male presented with reduced Glasgow Coma Scale (GCS) score, slurred speech, right-sided hemiparesis, and bitemporal hemianopia. Magnetic resonance imaging of the brain showed a large hemorrhagic sellar/suprasellar mass and an area of cortical T2/FLAIR hyperintensity with corresponding diffusion restriction in the middle cerebral artery territory. Computed tomography (CT) intracranial angiogram showed luminal occlusion of the clinoid and ophthalmic segments of both internal carotid arteries (ICAs, left>right) due to mass pressure effect. Biochemical investigations confirmed hyperprolactinemia and multiple pituitary hormone deficiencies. Stress-dose hydrocortisone was commenced with cabergoline, followed by urgent endoscopic transsphenoidal debulking of the tumor (subsequent histology showing prolactinoma). Postoperative CT angiogram showed improved caliber of ICAs. Intensive neurorehabilitation was implemented and resulted in complete recovery of motor and cognitive deficits. At the last assessment (18.8 years), the patient remained on complete anterior pituitary hormone replacement without cabergoline. Pituitary apoplexy is a medical emergency requiring prompt recognition and treatment and should be suspected in patients presenting with sudden, severe headache; nausea; or visual disturbance and meningism. Ischemic stroke is a rare manifestation of pituitary apoplexy in the pediatric population.

      • KCI등재

        Structure-rheology elucidation of human blood via SPP framework and TEVP modeling

        Matthew Armstrong,Jeff Baker,Jesse Trump,Erin Milner,J. Kenneth Wickiser,Kenneth Cameron,Nick Clark,Kaitlyn Schwarting,Thomas Brown,Dorian Bailey,Corey James,Chi Nguyen,Trevor Corrigan 한국유변학회 2021 Korea-Australia rheology journal Vol.33 No.1

        Recent work modeling the rheological behavior of human blood indicates that it has all the hallmark features of a complex material, including shear-thinning, viscoelastic behavior, a yield stress, and thixotropy. After decades of modeling steady state blood data, and the development of simple steady state models, like the Casson and Herschel-Bulkley the advancement and evolution of blood modeling to incorporate more thixo-elasto-visco-plastic (TEVP) features to accurately capture transient flow has renewed interest. With recently collected steady state and oscillatory shear flow rheological data from a DHR-3 using human blood, we show modeling efforts with a contemporary thixo-elasto-visco-plastic (TEVP) model. Best fit rheological model parameters are used to determine values for normal, h ealthy blood and corroborate correlations from literature. Series of physical processes (SPP) analysis is incorporated to illustrate how mechanical properties are tied to the transient, evolving microstructure of human blood and physiological parameters. Using LAOS data predictions of the structure parameter,  is compared, and correlated with the transient elastic modulus, .

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