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Structure-rheology elucidation of human blood via SPP framework and TEVP modeling
Matthew Armstrong,Jeff Baker,Jesse Trump,Erin Milner,J. Kenneth Wickiser,Kenneth Cameron,Nick Clark,Kaitlyn Schwarting,Thomas Brown,Dorian Bailey,Corey James,Chi Nguyen,Trevor Corrigan 한국유변학회 2021 Korea-Australia rheology journal Vol.33 No.1
Recent work modeling the rheological behavior of human blood indicates that it has all the hallmark features of a complex material, including shear-thinning, viscoelastic behavior, a yield stress, and thixotropy. After decades of modeling steady state blood data, and the development of simple steady state models, like the Casson and Herschel-Bulkley the advancement and evolution of blood modeling to incorporate more thixo-elasto-visco-plastic (TEVP) features to accurately capture transient flow has renewed interest. With recently collected steady state and oscillatory shear flow rheological data from a DHR-3 using human blood, we show modeling efforts with a contemporary thixo-elasto-visco-plastic (TEVP) model. Best fit rheological model parameters are used to determine values for normal, h ealthy blood and corroborate correlations from literature. Series of physical processes (SPP) analysis is incorporated to illustrate how mechanical properties are tied to the transient, evolving microstructure of human blood and physiological parameters. Using LAOS data predictions of the structure parameter, is compared, and correlated with the transient elastic modulus, .