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Ngoan Thi Nguyen,Dai Lam Tran,Duc Cuong Nguyen,Thai Loc Nguyen,Thi Cham Ba,Binh Hai Nguyen,Thi Duong Ba,Nam Hong Pham,Dzung Tuan Nguyen,Thai Hoa Tran,Gia Dien Pham 한국물리학회 2015 Current Applied Physics Vol.15 No.11
Nanocomposites containing two or more functional constituents are attractive candidates for advanced nanomaterials. In this study, multifunctional Ag/Fe3O4-CS nanocomposites were successfully prepared, using chitosan as a stabilizing and cross-linking agent. The as-synthesized nanocomposites were characterized by Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), X-ray diffraction (XRD), Energy-dispersive X-ray spectroscopy (EDS), UVevisible spectrophotometer (UVeVis) and vibrating sample magnetometer (VSM). The results demonstrated that Ag/Fe3O4-CS composite nanoparticles (NPs) were composed of parent components, Fe3O4 and Ag NPs, which were uniformly dispersed in the chitosan matrix. The hybrid NPs exhibited strong antibacterial property against Pseudomonas aeruginosa. With high magnetization value (67 emu/g), the synthesized Ag/Fe3O4-CS composite can be easily separated or recycled in potential biomedical applications. Furthermore, the results showed that the multicomponent hybrid nanostructures appeared to be the promising material for local hyperthermia, which can be used as thermoseeds for localized hyperthermia treatment of cancers.
Hong Thi Bich Truong,Hiep Nghia Bui,Hieu Trung Nguyen,Thanh-Luu Pham,Duy Ngoc Nguyen,Yuan-Shing Perng,Linh Thi My Lam,Thi-Dieu-Hien Vo,Van-Truc Nguyen,Ha Manh Bui 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.4
Electron-beam (EB) irradiation was employed to degrade enrofloxacin (ENR) in an aqueous solution. Thealgal growth inhibition test revealed that ENR exhibited low toxicity against the cyanobacterium Arthrospira sp., with anEC50-96 h value of 5.17mg/L. The Taguchi design also involved finding the best optimum for ENR treatment using EB. Results revealed that the high-efficiency removal of ENR in an aqueous solution was approximately 98.53% under theoptimum conditions of an absorbed dose of 5 kGy, a pH of 5.0, and an initial ENR concentration of 10 mg/L and anH2O2 concentration of 2mM. The ERR degradation under a couple of EB irradiation and H2O2 followed pseudo-firstorderkinetics, with an R2 of ~0.970. The major degradation pathways of ENR were suggested by density functional theory,natural bond orbital calculations, and liquid chromatography-tandem mass spectrometry (LC/MS/MS) analysis. Lifecycle assessment (LCA) was also performed to evaluate the impact of the EB on removing ENR; the industrial processwas designed based on laboratory tests aimed with the ReCiPe tool. The obtained results indicated that energy consumptionand H2O2 affect environmental impacts with order human health, ecology systems, and natural resource. The LCAalso proved that EB could be a green and efficient method for eliminating pharmaceutical contaminants in water.
New Dibenzocyclooctadiene Lignan from Kadsura induta and Their Cytotoxic Activities
Pham, Thi Hong Minh,Do, Tien Lam,Nguyen, Quyet Tien,Nguyen, Ngoc Tuan,Vu, Phuong Nhung,Nong, Van Hai,Phan, Van Kiem,Nguyen, Xuan Nhiem,Chau, Van Minh,Park, SeonJu,Kim, Seung Hyun Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.6
Tung Nguyen-Thach,Nguyen Canh-Hung,Nguyen Van-Duong,Nguyen Thi-Hong-Thuy,Nguyen Van-Lam,Tran Cao-Son,Pham Thi-Minh-Hue 한국약제학회 2020 Journal of Pharmaceutical Investigation Vol.50 No.4
Purpose The study aimed firstly to determine the release behavior of the model drug (berberine chloride) from the dry coated tablets. The second objective of this study was to evaluate the exact location of the dry coated tablets in in vivo. Methods The colon targeting tablets were developed by dry powder coating technique on pan coater. The drug release behavior was determined in the three continuous mediums: pH 1.2; 7.4 and 6.8 plus pectinase. The location of the dry coated tablets in the gastrointestinal tract of human volunteers was observed through the X-ray imaging of the dry coated tablets containing the optimized radiocontrast agents. Results The release kinetics of berberine chloride from the dry coated tablets was mainly controlled by erosion and enzyme sensitive mechanism. The optimum dry coated tablets having the coating powders of pectin 102:HPMC K4 M (2:1) with the coating level of 200%, and the tablet core with BaSO4 10% and iobitridol 30% as radiocontrast agents were observed in the caecum and ascending colon of human volunteers after 5–6 h of oral administration. Conclusion The successful development of these dosage forms is believed to have a high potential in precisely monitoring the release of highly potent drugs such as anti-inflammatory drugs in bowel diseases.
Duc Hieu PHAM,Thi Huyen CHU,Thi Minh Giang NGUYEN,Thi Hong Lam NGUYEN,Thi Nhinh NGUYEN 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.7
This paper aims to analyze whether company characteristics are potential determinants of human resource accounting (HRA) disclosure practices by Vietnamese listed companies. It examines the human resource disclosure level of 204 companies by content analysis of these companies’ annual reports. The study has relied on a multiple linear regression to test the association between a number of corporate attributes and the extent of human resource disclosure in companies’ annual reports. The extent of human resource disclosure was measured using unweighted human resource disclosure index. The explanatory variables considered in this study were firm size, firm age, profitability, leverage, industry profile, and auditor type. The results revealed that the most influential variable for explaining firms’ variation in human resource disclosure is firm size followed by firm age and profitability. Thus, it can be concluded that firm size, firm age and profitability are major predictors that may affect the variety of HRA disclosure practices on firms listed in the Vietnam Stock Exchange. However, neither industry profile nor auditor type seems to explain differences in human resource disclosure practices between Vietnamese listed firms, indicating that company’s industry profile and auditor type are not a matter for the company to disclose HRA information.