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대장암에서 림프절 침범과 암의 침윤도가 예후에 미치는 영향
최윤미 ( Yun Mee Choi ),김해성 ( Hae Sung Kim ),최선근 ( Sun Keun Choi ),허윤석 ( Yun Seok Hur ),이건영 ( Kun Yong Lee ),김세중 ( Sei Joong Kim ),안승익 ( Seung Ick Ahn ),홍기천 ( Kee Cheun Hong ),신석환 ( Seok Hwan Shin ),우제홍 대한소화기학회 2002 대한소화기학회지 Vol.40 No.6
Background/Aims: This study was carried out to evaluate prognostic significance of the clinicopathological features in colorectal cancer. Methods: The records of 413 patients who underwent a curative resection of colorectal cancer from June of 1996 to December of 2000 were examined focusing on the clinicopathological factors and difference of survival rates. Results: The numbers of lymph node metastasis were significantly related to age, depth of invasion, histologic differentiation, tumor size, lymphovascular invasion, perineural invasion, and preoperative serum CEA level. In the univariate analysis for 366 patients, the depth of invasion (p=0.0017), histologic differentiation (p=0.0069), lymph node metastasis (p=0.0000), lymphovascular invasion (p=0.0001), perineural invasion (p=0.0008), and preoperative serum CEA level (p=0.0005) turned out to be significant prognostic factors. The histologic differentiation between the primary lesion and the metastatic lymph node was the same in 90.7% of the studied cases. Capsular invasion was found in 92 cases (53.5%), but there was no significant difference in survival rates between the capsular invasion group and non-capsular invasion group (p=0.0510). Conclusions: In this study, the depth of invasion, lymph node metastasis, and the number of lymph node metastasis could be recognized as important prognostic factors for colorectal cancer. However, further follow-up studies are needed to determine the role of the various clinical and pathological factors in colorectal cancer prognosis. (Korean J Gastroenterol 2002;40:371-378)
강보영,한승정,이지은,최선근,김준미,홍영진,손병관,Kang, Bo-Young,Han, Seung-Jeong,Lee, Ji-Eun,Choi, Sun-Kun,Kim, Jun-Mi,Hong, Young-Jin,Son, Byong-Kwan 대한소아소화기영양학회 2003 Pediatric gastroenterology, hepatology & nutrition Vol.6 No.2
저자들은 전신부종과 심한 저알부민혈증으로 내원한 환아에서 테그네슘표지 인혈청알부민 스캔을 이용하여 결장에서 단백이 소실되는 것을 확인하고, 바륨 관장 대장 조영술 검사, 상부 위장관 촬영, 소장 조영술, 대장과 십이지장 내시경 검사를 통해 단백 소실 장증으로 발현한 연소성 용종증을 진단하여, 전대장 절제술 후 단백 소실 장증이 호전된 증례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Juvenile polyposis is an uncommon condition characterized by the development of multiple juvenile polyps predominantly in the colon but also in the rest of the gastrointestinal tract. Patients with juvenile polyposis commonly present with rectal bleeding, diarrhea, abdominal pain, anemia, prolapse of the polyp. We experienced a juvenile polyposis in a 7 year-old male patient with protein losing enteropathy who was diagnosed by $^{99M}Tc$-human serum albumin abdominal scintigraphy, colonoscopy, and small bowel series. Proctocolectomy with ileostomy was performed and then protein losing enteropathy was resolved.