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( Sumin Oh ),( Hyun Hoon Chung ),( Jae Weon Kim ),( Yong Sang Song ),( Noh Hyun Park ),( Yoo Kyung Lee ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.99 No.-
Objective: Despite the good prognosis of borderline ovarian tumors (BOTs), a few BOT patients experience the relapse of disease. Among them, some reveal the cancerous disease, however, the risk of malignant transformation of BOT is usually thought to be unclear. We intended to find out the specific characteristics and prognosis of cancerous recurrence from BOTs. Methods: Between 1995 and 2012, 130 women were diagnosed with BOTs in our institution. Seven patients diagnosed and treated for cancerous recurrence of BOTs were included for analysis in this retrospective study. Clinicopathological characteristics and surgical procedure as well as follow-up data with overall survival were assessed. Statistical analyses included the χ2 test, t-test and Log-rank test with Cox regression. Result: One hundred and thirty patients with mean follow-up of 65.8 months (range, 1 to 241 months) were evaluated, of whom half were below 40 years-old at their first diagnosis of BOTs and 53.8% received conservative surgery. In our cohort, mucinous pathologic type was the most common one (66.9%). Among 11 patients who were diagnosed relapse of BOTs (8.5%), seven cancerous transformations were detected (5.4%) with median time of 9 months (range, 1 to 54 months). All cancerous relapses arose from premenopausal women of median age of 35 years old. Tumor size and tumor markers level (CA-125 and CA 19-9) did not show any predictive value for the malignant transformation of BOTs. Laparoscopic approach and conservative surgery were revealed that had no significant influence on relapse and overall survival (p=0.602, p=0.543). The median survival time of cancerous recurrent cases is 9 months (range, 3 to 31 months). Among them, four died of recurrent disease (ovarian cancer) and the other 3 has been reached complete remission. Conclusion: Minimal invasive conservative surgery for BOTs can be accepted under close follow-ups. However, survival rate of disease can be expected to be poor if malignant transformation of BOTs occurred.
Perioperative and postoperative morbidity after sacrocolpopexy according to age in Korean women
( Sumin Oh ),( So Hyun Shin ),( Ji Young Kim ),( Maria Lee ),( Myung Jae Jeon ) 대한산부인과학회 2015 Obstetrics & Gynecology Science Vol.58 No.1
Objective This study aimed to compare perioperative and postoperative morbidity of older and younger women undergoing sacrocolpopexy (SCP). Methods A retrospective study included 271 patients who underwent laparotomic SCP for symptomatic pelvic organ prolapse from November 2008 to June 2013 at our institution. By the review of medical records, perioperative and postoperative data including the length of the surgery, estimated blood loss, blood transfusion, the length of hospital stay, wound complications and febrile morbidity were collected. In addition, cardiovascular, pulmonary, gastrointestinal, genitourinary,or neurological adverse events were retrieved. The need for an indwelling urinary catheter or performance of clean intermittent self-catheterization, mesh erosion rate and the number of days required for each were included in the postoperative outcomes. For the outcome variable analyzed in this study, the patients was dichomotized into women aged 65 and older and those younger than 65. Results One hundred and thirty-five (49.8%) patients were younger than 65 and 136 (50.2%) were aged 65 and older. Older women had higher body mass index, vaginal parity and prior surgery for hysterectomy than younger women (P<0.05). And older women had higher baseline comorbidities, such as hypertension, diabetes, cardiac disease (P<0.05), and theirAmerican society of Anesthesiologist class was higher (P<0.001). In the perioperative and postoperative complication, older group showed no differences in most of the operation-related complication rates, but gastrointestinal complication rate. Also, mesh erosion rate was not found to be significantly different between the two groups at the last visit. Conclusion Older women undergoing laparotomic SCP have similar perioperative and postoperative morbidities as younger women, suggesting surgeons can counsel older and younger women similarly in terms of operative risks.
Oh, Sumin,Oh, Sejong Korea Genome Organization 2014 Genomics & informatics Vol.12 No.3
Gastritis is a major disease that has the potential to grow as gastric cancer. Gastric cancer is a very common cancer, and it is related to a very high mortality rate in Korea. This disease is known to have various reasons, including infection with Helicobacter pylori, dietary habits, tobacco, and alcohol. The incidence rate of gastritis has reported to differ between age, population, and gender. However, unlike other factors, there has been no analysis based on gender. So, we examined the high risk factors of gastritis in each gender in the Korean population by focusing on sex. We performed an analysis of 120 clinical characteristics and genome-wide association studies (GWAS) using 349,184 single-nucleotide polymorphisms from the results of Anseong and Ansan cohort study in the Korea Association Resource (KARE) project. As the result, we could not prove a strong relation with these factors and gastritis or gastric ulcer in the GWAS. However, we confirmed several already-known risk factors and also found some differences of clinical characteristics in each gender using logistic regression. As a result of the logistic regression, a relation with hyperlipidemia, coronary artery disease, myocardial infarction, hyperlipidemia therapy, hypotensive or antihypotensive drug, diastolic blood pressure, and gastritis was seen in males; the results of this study suggest that vascular disease has a potential association with gastritis in males.
( Sumin Oh ),( Hye Ryun Namkung ),( Hee Yeon Yoon ),( So Yeon Lee ),( Myung Jae Jeon ) 대한산부인과학회 2022 Obstetrics & Gynecology Science Vol.65 No.1
Objective To identify the factors associated with unsuccessful pessary fitting and reasons for pessary discontinuation in Korean women with pelvic organ prolapse (POP). Methods The medical records of 234 patients who underwent pessary fitting for the management of symptomatic POP were retrospectively reviewed. A ring pessary with or without support was used. Successful pessary fitting was defined as the ability to wear a pessary for 2 weeks without any discomfort. Factors associated with unsuccessful pessary fitting were determined using a multivariable logistic regression analysis. A Kaplan-Meier survival curve was obtained to examine the probability of continuing pessary use over the follow-up period. The reasons for the discontinuation of pessary were identified. Results Two-hundred-and-twenty-five women were included in the analysis. The rate of unsuccessful pessary fitting was 40%. Prior hysterectomy (odds ratio [OR], 4.13; 95% confidence interval [CI], 1.81-9.42) and POP quantification stage III-IV (OR, 2.49; 95% CI, 1.28-4.85) were independent risk factors for unsuccessful pessary fitting. Among the patients with successful pessary fitting, the median time to discontinuation of pessary use was 4 years. The most common causes of discontinued use were vaginal erosion (45.3%) and urinary incontinence (26.5%). Conclusion Patients with a history of hysterectomy and advanced-stage POP are at risk for an unsuccessful fitting of the ring pessary. Vaginal erosion is the main reason for discontinued use among patients with successful pessary fitting.
Sumin Oh,Sunghoon Jung 한국응용곤충학회 2017 한국응용곤충학회 학술대회논문집 Vol.2017 No.04
The leafhopper subfamily, Typhlocybinae (Hemiptera: Auchenorrhyncha: Cicadellidae), caused direct damage by sap-sucking or indirect damage by transmission of viruses or diseases to the host plants, so Typhlocybinae is one of the most important insect pests in agriculture, urban ecology, forest, etc. in the world. However, their identifications are very difficult due to small size and morphological similarities, and their exact biological information such as host plants and life cycle are not reported yet for most species. So, we construct an integrated biological database that presents accurate diagnostic methods (illustrated key characters, DNA barcoding data), patterns and seasons of occurrences, and some ecological photographs such as dorsal habitus of specimens and plant damages
Sumin Oh,Sunghoon Jung 한국응용곤충학회 2016 한국응용곤충학회 학술대회논문집 Vol.2016 No.04
Leafhopper subfamily, Typhlocybinae (Hemiptera: Auchenorrhyncha: Cicadellidae), caused direct damage by sap-sucking or indirect damage by transmission of viruses or diseases on the host plants, so typhlocybinae is one of the important pest groups in the world. Typhlocybinae distribute worldwide and a total of 471 genera and more than 4,300 species have been described. so far, 38 genera and 102 species were recorded in the Korean Peninsula. In this talk, we provide several taxonomic studies for the Korean typhlocybene fauna based on the genus-level reviews of the subfamily from the Korean Peninsula.