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Sukwon Kim,Yoonsun Nam,Eungkyo Suh 한국차세대컴퓨팅학회 2023 한국차세대컴퓨팅학회 학술대회 Vol.2023 No.12
This research proposes the development of an online psychological counseling platform utilizing an Artificial Intelligence (AI)-based emotion analysis system. The platform, leveraging facial video, voice, and text data, aims to real-time identify and analyze the emotional states of counselees in a non-face-to-face counseling environment, providing counselors with the necessary information to facilitate appropriate counseling. The outcomes of this research are expected to enhance communication effectiveness between counselors and counselees and contribute to the psychological well-being of counselees in online counseling scenarios.
( Hye Young Kim ),( Kwang Woong Lee ),( Sukwon Suh ),( Min Su Park ),( Youngrok Choi ),( Geun Hong ),( Hae Won Lee ),( Nam Joon Yi ),( Kyung Suk Suh ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1
Background/Aim: Hepatitis C virus (HCV) recurrence after liver transplantation (LT) is universal and progressive. To date, there is no general consensus about modality, timing and dosing of anti-HCV treatment in recipients. Serial liver biopsies remain the best way of monitoring disease progression, and recently, there is a trend of that protocol biopsy based HCV treatment is recommended than biochemical abnormality based treatment. However, little is known about the results of protocol biopsy in patient with normal graft function after LT regardless of clinical significance, especially in Korea. The aim of this study was to evaluate the usefulness of early protocol biopsy after LT in patients of HCV related liver disease. Methods: We have performed a protocol biopsy at specific time points (3 months, 6 months and 12 months after LT) in patient who underwent LT due to HCV related liver disease at Seoul National University Hospital since 2010. In this study, we retrospectively reviewed the results of protocol biopsy in HCV related liver recipients between January 2010 and December 2011. In case of presence of fibrosis or inflammation more than moderate degree in histology irrespective of liver function test (LFT) results, we started HCV treatment. Additionally, in case of significant LFT abnormality with histologic mild hepatitis, we started HCV treatment also. Results: Total 30 patients (8.9%) underwent LT due to HCV related liver disease among 337 recipients for 2 years at our center. Among them, 19 patients (63.3%, 19/30) underwent protocol biopsy within a year after LT. Twelve patients underwent living donor LT and 7 patients deceased donor LT. Eight patients (42.1%) had a coexisting hepatocellular carcinoma. The genotype I and II were 42.1% and 31.6%, respectively. Main immunosuppressant was tacrolimus (78.9%, 15/19). No significant complication after the sono-guided needle biopsy was reported. With the specific time points of biopsy, 11 patients underwent protocol biopsy at 3 months, 11 patients at 6 months and 6 patients at 12 months after LT, respectively. Treatment for HCV infection was started in 3 patients (27.3%, 3/11; due to 2 fibrosis, 1 significant LFT abnormality with histologic mild hepatitis) after the protocol biopsy at 3 month, 6 patients (54.5%, 6/11; due to 3 fibrosis, 2 moderate inflammation, 1 significant LFT abnormality with histologic mild hepatitis) at 6 month, 2 patient (33.3%, 2/6; due to 2 fibrosis) at 12 months following LT. As the results, 57.9% (n = 11) underwent HCV treatment within a year after LT based on protocol biopsy. Furthermore, among the 11 patients, 81.8% (n = 9) showed norma \l LFT. Conclusions: In HCV related recipients, more than a half went into HCV treatment after protocol biopsy within a year after LT. Based on our study, at 3 months, 6 months, 12 months and then annually after LT, protocol biopsy is needed in HCV related liver transplant recipients.