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      • Foot Ulcers and Sleep Quality in Type 2 Diabetes Mellitus

        Suiçmez Eylem,Tural Egemen,Dayan Akın 대한수면학회 2024 sleep medicine research Vol.15 No.1

        Background and Objective The study aimed to investigate the sleep quality of type 2 diabetic patients with and without foot ulcers, to determine whether there was a difference in sleep quality between them, and to examine the effect of diabetic foot ulcers on sleep quality.Methods Our prospective cross-sectional study was conducted between April and September 2021 at the Family Medicine Diabetes Clinic and Diabetic Foot Clinic of the hospital. A total of 146 patients were included in the study, of whom 64 had foot ulcers and 82 did not, and met the inclusion criteria. The patients were administered a patient information questionnaire that included sociodemographic data, waist circumference, HbA1c, diabetes duration, diabetes complication information, as well as the Pittsburgh Sleep Quality Index.Results The mean age of the individuals participating in the study was 61.94 ± 10.34 years. According to the Pittsburgh Sleep Quality Index classification, 25.0% (n = 16) of individuals with diabetic foot ulcers had good sleep quality while 42.7% (n = 35) of individuals without diabetic foot ulcers had good sleep quality. A statistically significant relationship was found between diabetic foot ulcers and Pittsburgh Sleep Quality Index classification (p = 0.026). According to the multivariate logistic regression model, diabetic foot ulcers increased the risk of poor sleep quality by 2.64 times.Conclusions Our study showed that the presence of diabetic foot ulcers adversely affects sleep quality. Good sleep quality contributes to quality of life, wound healing, and diabetes control. Therefore, improving sleep quality in diabetic foot patients is important.

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      • KCI등재

        Investigation of the origin of abnormal grain growth in the sintering process of Sr0.5Ba0.5Nb2O6 ceramics without eutectic liquid-phase

        Sui Wanmei,Luan Shijun,Song Ranran,Wang Chunlong 한양대학교 세라믹연구소 2011 Journal of Ceramic Processing Research Vol.12 No.6

        Abnormal grain growth in the traditional sintering process of (SrxBax−1)Nb2O6 limites its application and the localized liquidphase exsisting is regarded the main reason for the presence of abnormal grain growth. To prevent the presence of a localized liquid-phase, the sol-gel method was employed to synthesize nano-sized powders of Sr0.5Ba0.5Nb2O6, which was followed by a pure solid-phase sintering process of nano-sized powders to observe the evolution of the grain morphology. SEM observation revealed that the abnormal and preferential rod-like grain growth along the c-axis existed in the pure state-phase sintering for the Sr0.5Ba0.5Nb2O6 material companied with some of the smaller grains being diminished or consumed. This behavior would exist in the traditional solid-phase sintering with or without the localized liquid-phase. This would be another important factor to aid the abnormal grain growth and should be prevented in the manufacturing process. The effects of grain sizes on the dielectric constant, Tc and diffuse phase transion (DPT) were observed in the Sr0.5Ba0.5Nb2O6 ceramics.

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        Der p2 Internalization by Epithelium Synergistically Augments Toll-like Receptor-Mediated Proinflammatory Signaling

        Sui-Chu Yin,En-Chih Liao,Chih-Liang Chiu,Ching-Yun Chang,Jaw-Ji Tsai 대한천식알레르기학회 2015 Allergy, Asthma & Immunology Research Vol.7 No.4

        Purpose: House-dust-mite (HDM) major allergen Der p2 shares homology and function with Toll-like receptor (TLR) signaling protein myeloid differentiation- 2 (MD2) and may lead to airway inflammation. Should Der p2 be internalized by human airway epithelium, it has the theoretical propensity to potentiate epithelium activation. This study aimed to demonstrate the internalization of Der p2 by airway epithelium and to investigate the effects of Der p2 on MD2 expression and epithelium activation. Methods: Internalization of recombinant, enhanced green fluorescent protein-labelled Der p2 (rDer p2-EGFP) into human airway epithelium (BEAS-2B) was tracked by laser confocal microscopy and confirmed by immunoblotting. Reverse-transcription polymerase chain reaction (RT-PCR), immunoblotting, and immunohistochemical staining were used to determine the effect of Der p2 on MD2 expression in vitro and ex vivo. Expression of messenger RNA (mRNA) encoding receptors/cytokines was measured by RT-PCR. Secretion of interleukin-6/interleukin-8 (IL-6/IL-8) was measured by enzyme-linked immunosorbent assay (ELISA). Results: Internalization of Der p2 by BEAS-2B was confirmed by confocal microscopy and immunoblotting using rDer p2-EGFP and rDer p2, respectively. Expression of MD2 protein was increased in BEAS-2B and human nasal polyp airway epithelium cultured with rDer p2. Recombinant Der p2-cultured BEAS-2B caused little spontaneous IL-6/IL-8 secretion but significantly augmented by TLR ligand LPS. IL-6 secretion was up-regulated after MD2 transfection. Internalization of Der p2 was reduced by TLR2 RNA knockdown. Dexamethasone, calcitriol, anti-MD2/anti-TLR2 antibodies, and signalling inhibitors significantly reduced LPS+Der p2-induced IL-6/IL-8 secretion. Conclusions: Human airway epithelium may internalize Der p2, which potentiates the response to environmental proinflammatory stimuli through MD2 and TLRs. This study highlights a novel mechanism and alleviates IL-6/IL-8 secretion in mite-induced airway inflammation

      • An Improved Modulation Scheme for Voltage Balancing in Modular Multilevel Converter

        Sui, Shunke,Yang, Rongfeng,Xu, Dianguo The Korean Institute of Electrical Engineers 2014 The Journal of International Council on Electrical Vol.4 No.2

        With the continuous development of power electronic technology toward the high voltage and high-power conversion, the Modular Multilevel Converter (MMC) has attracted research attention. Since a large number of capacitors, voltage balancing problem becomes one of the key technologies of the MMC. To resolve the voltage balancing problem, this paper presents a novel voltage balancing modulation scheme, which control the instantaneous power of each sub-module timely by adjusting carriers offset in PWM, and the respective capacitor voltage could be stabilized at a set value. Simulation results based on MATLAB / SIMULINK environment are provided to testify to the effectiveness of the proposed method.

      • Mini droplets to super droplets: evolution of self-assembled Au droplets on GaAs(111)B and (110)

        Sui, Mao,Li, Ming-Yu,Kim, Eun-Soo,Lee, Jihoon International Union of Crystallography 2014 Journal of applied crystallography Vol.47 No.2

        <P>In this article, the effect of deposition amount on self-assembled Au droplets fabricated on GaAs(111)B and (110) is presented. The investigation is systematically performed by the variation of the Au deposition amount from 2 to 20 nm while fixing the other growth parameters such as annealing temperature and duration to clearly observe the effect. Under identical growth conditions, the self-assembled Au droplets show significantly different size and density depending on the amount of Au deposition:<I>i.e.</I>the average height varies by 436% from 21.8 to 95.5 nm and the average diameter swings by 827% from 52 to 430 nm, showing that the size increase is dominated by the lateral expansion. Meanwhile the average density varies by over two orders of magnitude from 1.24 × 10<SUP>8</SUP>to 4.48 × 10<SUP>10</SUP> cm<SUP>−2</SUP>on GaAs(111)B. With relatively low Au deposition amounts, below 3 nm, round dome-shaped mini Au droplets with high packing density can be fabricated, while super large Au droplets result with higher deposition amounts, above 10 nm, with a density two orders of magnitude lower. It is also found that the surface index has a minor effect on the fabrication of self-assembled Au droplets with the variation of deposition amount. The results are systematically analyzed and discussed in terms of atomic force microscopy and scanning electron microscopy images, line profiles, power spectrums, r.m.s. surface roughness, and size and density plots.</P>

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        Fabrication and determination of growth regimes of various Pd NPs based on the control of deposition amount and temperature on <i>c</i>-plane GaN

        Sui, Mao,Kunwar, Sundar,Pandey, Puran,Zhang, Quanzhen,Li, Ming-Yu,Lee, Jihoon Published for the Materials Research Society by th 2017 Journal of materials research Vol.32 No.18

        <▼1><B>Abstract</B><P/></▼1><▼2><P>Palladium (Pd) nanostructures have been actively adapted for various applications and their properties and applicability closely depend on their shape, size, and density. In this paper, the evolution of self-assembled Pd nanostructures on the hexagonal <I>c</I>-plane GaN is presented by the systematical control of Pd deposition amount (DA) at distinctive temperatures. Pd nanostructures of various configurations, sizes, and densities are demonstrated based on the solid-state dewetting of Pd thin films and a clear distinction in the growth regimes is observed. Three growth regimes are clearly observed depending on the variation of DA, i.e., (i) the agglomeration of Pd nanoparticles, (ii) the coalescence of wiggly Pd nanostructures, and finally (iii) the growth of nanovoids and layers. Owing to the temperature-dependent dewetting process, the growth regimes are markedly shifted, resulting in the distinctive Pd nanostructures within the identical DA range. The results are discussed in conjunction with the surface diffusion, Volmer-Weber and coalescence growth model, and surface/interface energy minimization mechanism. In addition, the evolution of optical properties, emission band, and lattice properties are probed by reflectance, photoluminescence, and Raman spectroscopy, which exhibit varying spectral intensity and peak positions according to the surface morphology of Pd nanostructures.</P></▼2>

      • Fabrication of self-assembled Au droplets by the systematic variation of the deposition amount on various type-B GaAs surfaces

        Sui, Mao,Li, Ming-Yu,Kim, Eun-Soo,Lee, Jihoon Springer 2014 NANOSCALE RESEARCH LETTERS Vol.9 No.1

        <P>The fabrication of self-assembled Au droplets is successfully demonstrated on various GaAs (<I>n</I>11)B, where <I>n</I> is 2, 4, 5, 7, 8, and 9, by the systematic variation of the Au deposition amount (DA) from 2 to 12 nm with subsequent annealing at 550°C. Under an identical growth condition, the self-assembled Au droplets of mini to supersizes are successfully synthesized via the Volmer-Weber growth mode. Depending on the DA, an apparent evolution is clearly observed in terms of the average height (AH), lateral diameter (LD), and average density (AD). For example, compared with the mini Au droplets with a DA of 2 nm, AH of 22.5 nm, and LD of 86.5 nm, the super Au droplets with 12-nm DA show significantly increased AH of 316% and LD of 320%, reaching an AH of 71.1 nm and LD of 276.8 nm on GaAs (211)B. In addition, accompanied with the dimensional expansion, the AD of Au droplets drastically swings on 2 orders of magnitudes from 3.2 × 10<SUP>10</SUP> to 4.2 × 10<SUP>8</SUP> cm<SUP>-2</SUP>. The results are systematically analyzed with respect to the atomic force microscopy (AFM) and scanning electron microscopy (SEM) images, energy-dispersive X-ray spectrometry (EDS) spectra, cross-sectional line profiles, Fourier filter transform (FFT) power spectra, and root-mean-square (RMS) roughness as well as the droplet dimension and density summary, respectively.</P>

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