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( Yasunari Sakamoto ),( Shingo Kato ),( Yusuke Sekino ),( Eiji Sakai ),( Takashi Uchiyama ),( Hiroshi Iida ),( Kunihiro Hosono ),( Hiroki Endo ),( Koji Fujita ),( Tomoko Koide ),( Hirokazu Takahashi ) 대한소화기기능성질환·운동학회 2011 Journal of Neurogastroenterology and Motility (JNM Vol.17 No.2
Background/Aims There are few reports on the correlation between chewing gum and the gastrointestinal functions. But previous report showed use of chewing gum to be an effective method for controlling gastrointestinal symptoms. The aim of this study was to determine the correlation between chewing gum and gastric emptying using the continuous real time 13C breath test (BreathID system). Methods Ten healthy male volunteers participated in this randomized, 2-way crossover study. The subjects fasted overnight and were randomly assigned to chewing gum (Xylish, 2-3/1 tablet) for an hour following intake of a test meal (200 kcal/200 mL) or intake of the test meal alone. Gastric emptying was monitored for 4 hours after administration of the test meal by the 13C-acetic acid breath test performed continually using the BreathID system. Results No significant differences in the calculated parameters, namely, T1/2 (median, 111.82 vs 109.26 minutes; P = 0.575), Tlag (median, 53.28 vs 56.53 minutes; P = 0.333), gastric emptying coefficient (median, 3.58 vs 3.65; P = 0.285), regression-estimated constant β (median, 1.85 vs 1.80; P = 0.575) and regression-estimated constant κ (median, 0.61 vs 0.62; P = 0.959) were observed between the test meal alone group and the test meal and chewing gum group. Conclusions This study showed that chewing gum had no effect on the rate of gastric emptying. Therefore, since chewing gum did not enhance the speed of gastric emptying, it may ameliorate gastrointestinal symptoms through other mechanisms, such as saliva and autonomic nervous system. (J Neurogastroenterol Motil 2011;17:174-179)
Lim, Jong-hwan,Shingo Sakamoto,Jang, Beom-su,Lee, Rae-kyung,Park, Seung-chun,Cho, Joon-hyoung,Jeong, Sang-hee,Yun, Hyo-in 충남대학교 수의과대학 동물의과학연구소 1999 動物醫科學硏究誌 Vol.7 No.-
A highly sensitive and specific method for the determination of furaltadone in the poultry muscle by LC/MS was developed and validated. A dichloromethane extract of the sample was cleaned up with SPE, separated on a C_18 reversed-phase column with the mobile phase of 10 mM ammonium acetate and methanol and acetonitrile (1:3:6, V/V/V) and analyzed by LC/MS with atmospheric pressure ionization/electrospray ionization interface. The limit of detection and limit of quantitation were 1 ng/g and 5 ng/g, respectively. The precision was expressed by coefficients of variation and was ranged from 3.0% to 11.8%. The method has been successfully applied to determine furaltadone concentration in the poultry muscle for the depletion study of furaltadone.
Shuhei Sawayama,Nurjannah Nurdin,Muhammad Akbar AS,Shingo X Sakamoto,Teruhisa Komatsu 한국해양과학기술원 2015 Ocean science journal Vol.50 No.2
Coral reef ecosystems worldwide are now being harmed by various stresses accompanying the degradation of fish habitats and thus knowledge of fish-habitat relationships is urgently required. Because conventional research methods were not practical for this purpose due to the lack of a geospatial perspective, we attempted to develop a research method integrating visual fish observation with a seabed habitat map and to expand knowledge to a two-dimensional scale. WorldView-2 satellite imagery of Spermonde Archipelago, Indonesia obtained in September 2012 was analyzed and classified into four typical substrates: live coral, dead coral, seagrass and sand. Overall classification accuracy of this map was 81.3% and considered precise enough for subsequent analyses. Three sub-areas (CC: continuous coral reef, BC: boundary of coral reef and FC: few live coral zone) around reef slopes were extracted from the map. Visual transect surveys for several fish species were conducted within each sub-area in June 2013. As a result, Mean density (Ind. / 300 m2) of Chaetodon octofasciatus, known as an obligate feeder of corals, was significantly higher at BC than at the others (p < 0.05), implying that this species’ density is strongly influenced by spatial configuration of its habitat, like the “edge effect.” This indicates that future conservation procedures for coral reef fishes should consider not only coral cover but also its spatial configuration. The present study also indicates that the introduction of a geospatial perspective derived from remote sensing has great potential to progress conventional ecological studies on coral reef fishes.