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      • KCI등재

        A review of the preparation and applications of MnO2 composites in formaldehyde oxidation

        Shengnan Guan,Wenzhi Li,Jianru Ma,Yanyan Lei,Yuanshuai Zhu,Qifu Huang,Xiaomeng Dou 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.66 No.-

        This paper reviews several important preparation methods, and several kinds of MnO2 composites, which is efficient in formaldehyde catalytic oxidation. The preparation of MnO2 composites discussed in this article refer to sol–gel method, rheological phase reaction method, micro-emulsion method, chemical coprecipitation method, solid-phase synthesis and template method. After a presentation of methods for the preparation of MnO2, a review of the performance on formaldehyde catalytic oxidation over (I) manganese oxides; (II) metal–MnO2 oxide composites; (III) graphene–MnO2 composites is provided. The mechanisms for catalytic oxidation of HCHO over MnO2 composites, future directions and potential hotspots are also discussed to facilitate understanding.

      • KCI등재

        Numerically Study of the Flow Field and Spatter Particles in Laser-based Powder Bed Fusion Manufacturing

        Jiayue Wang,Yuwen Zhu,Hui Li,Sheng Liu,Shengnan Shen,Lei Wang,Shifeng Wen 한국정밀공학회 2022 International Journal of Precision Engineering and Vol.9 No.4

        Laser-based powder bed fusion (L-PBF) is an additive manufacturing (AM) technology that uses a high-energy–density laser to scan through a powder bed and completely melts the metal powder. The environment inside the printer chamber, including the flow field of the shielding gas and the spatter particles induced by laser–powder interactions, is essential for product quality. For the first time, this work built a full-size model of printer chamber, and numerically investigated the interaction between the shielding argon flow and the laser induced spatter particles with considering laser temperature. A full-size geometric model of a commercial L-PBF printer with a Gaussian heat source was constructed, as well as a movable particle-release source model for particle injection. The distribution of the argon flow field, the temperature field, and the trajectory and deposition of spatter particles, particularly above the workbench during the L-PBF process were quantitatively analyzed. The results show that the gas flow within 30 mm above the workbench is uniform, and in the upper region of the printer chamber, the flow field is disorderly. The laser can only induce high temperature and upward gas flow in a small region close to the workbench (the height less than 1.6 mm), and the laser induced velocity disturbance in rest regions of the L-PBF printer is negligible. Particles injected towards the outlet (ID4) are mostly blown into the outlet, and in the other four injection directions, more than 90% of spatter particles are deposited inside the printer chamber, especially more than 50% deposited on the workbench. Increasing the laser power (from 100 to 200 W) has little effect on particle deposition on the workbench. Results will be helpful for improving the L-PBF product quality.

      • KCI등재

        Sox12 Is a Cancer Stem-Like Cell Marker in Hepatocellular Carcinoma

        Zou, Song,Wang, Chen,Liu, Jiansheng,Wang, Qun,Zhang, Dongdong,Zhu, Shengnan,Xu, Shengyuan,Kang, Mafei,He, Shaozhong Korean Society for Molecular and Cellular Biology 2017 Molecules and cells Vol.40 No.11

        Recent studies on molecular carcinogenesis suggest that the chemo-resistance of some cancers is largely due to presence of cancer stem cells (CSCs), which affect the chemotherapy outcome for hepatocellular carcinoma (HCC). However, currently no consensus on a CSC phenotype in HCC has been obtained. Here, we examined Sox12 as a novel CSC marker in HCC. Sox12+ versus Sox12- cells were purified from HCC cell lines. The Sox12+ cells were compared with Sox12- HCC cells for tumor sphere formation, chemo-resistance, tumor formation after serial adoptive transplantations in nude mice, and the frequency of developing distal metastasis. We found that compared to Sox12- HCC cells, Sox12+ HCC cells generated significantly more tumor spheres in culture, were more chemo-resistant to cisplatin, were detected in circulation more frequently, and formed distal tumor more frequently. Moreover, Sox12 appeared to functionally contribute to the stemness of HCC cells. Thus, we conclude that Sox12 may be a novel marker for enriching CSCs in HCC.

      • KCI등재

        Sox12 Is a Cancer Stem-Like Cell Marker in Hepatocellular Carcinoma

        Song Zou,Chen Wang,Jiansheng Liu,Qun Wang,Dongdong Zhang,Shengnan Zhu,Shengyuan Xu,Mafei Kang,Shaozhong He 한국분자세포생물학회 2017 Molecules and cells Vol.40 No.11

        Recent studies on molecular carcinogenesis suggest that the chemo-resistance of some cancers is largely due to presence of cancer stem cells (CSCs), which affect the chemotherapy outcome for hepatocellular carcinoma (HCC). However, currently no consensus on a CSC phenotype in HCC has been obtained. Here, we examined Sox12 as a novel CSC marker in HCC. Sox12+ versus Sox12- cells were purified from HCC cell lines. The Sox12+ cells were compared with Sox12- HCC cells for tumor sphere formation, chemo-resistance, tumor formation after serial adoptive transplantations in nude mice, and the frequency of developing distal metastasis. We found that compared to Sox12- HCC cells, Sox12+ HCC cells generated significantly more tumor spheres in culture, were more chemo-resistant to cisplatin, were detected in circulation more frequently, and formed distal tumor more frequently. Moreover, Sox12 ap-peared to functionally contribute to the stemness of HCC cells. Thus, we conclude that Sox12 may be a novel marker for enriching CSCs in HCC.

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