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      • KCI등재

        Nonlinear Cascade Control for a New Coaxial Tilt-rotor UAV

        Shengming Li,Lin Feng,Zongyang Lv,Yuhu Wu,Yingshun Li 제어·로봇·시스템학회 2022 International Journal of Control, Automation, and Vol.20 No.9

        This paper proposes a nonlinear control strategy for a newly-designed coaxial tilt-rotor (CTR) unmanned aerial vehicle (UAV), which is a special class of tilt-rotor (TR) UAVs with two pairs of coaxial rotors, two servos, and a rear rotor. The CTRUAV is an underactuated system, and the controller is designed in cascade form. The proposed controller includes two sub-controllers: an inner-loop attitude controller and an outer-loop velocity controller. Each sub-controller is proposed by using a backstepping-like feedback linearization method to control and stabilize the CTRUAV. The developed control strategy can realize the motion control for the CTRUAV. The asymptotic stability of the resulting closed-loop system is analyzed by the Lyapunov method. Finally, simulations and real flight tests are performed to validate the effectiveness of the proposed control system.

      • KCI등재

        Early IL-17A Prevention Rather Than Late IL-17A Neutralization Attenuates Toluene Diisocyanate-Induced Mixed Granulocytic Asthma

        Chen Shuyu,Yu Li,Deng Yao,Liu Yuanyuan,Wang Lingwei,Li Difei,Yang Kai,Liu Shengming,Tao Ailin,Chen Rongchang 대한천식알레르기학회 2022 Allergy, Asthma & Immunology Research Vol.14 No.5

        Purpose: Interleukin (IL)-17A plays a critical role in the pathogenesis of allergic airway inflammation. Yet, the exact roles of IL-17A in asthma are still controversial. Thus, the aim of this study was to dissect the roles of IL-17A in toluene diisocyanate (TDI)-induced mixed granulocytic asthma and to assess the effects of neutralizing antibody in different effector phases on TDI-induced asthma. Methods: IL-17A functions in allergic airway inflammation were evaluated using mice deficient in IL-17A (Il17a−/−) or IL-17A monoclonal antibody (IL-17A mab, intraperitoneally, 50 μg per mouse, 100 μg per mouse). Moreover, the effects of exogenous recombinant IL (rIL)-17A in vivo (murine rIL-17A, intranasally, 1 μg per mouse) and in vitro (human rIL-17A, 100 ng/mL) were investigated. Results: TDI-induced mixed granulocytic airway inflammation was IL-17A-dependent because airway hyperreactivity, neutrophil and eosinophil infiltration, airway smooth muscle thickness, epithelium injury, dysfunctional T helper (Th) 2 and Th17 responses, granulocytic chemokine production and mucus overproduction were more markedly reduced in the Il17a−/− mice or by IL-17A neutralization during the sensitization phase of wild-type (WT) mice. By contrast, IL-17A neutralization during the antigen-challenge phase aggravated TDI-induced eosinophils recruitment, with markedly elevated Th2 response. In line with this, instillation of rIL-17 during antigen sensitization exacerbated airway inflammation by promoting neutrophils aggregation, while rIL-17A during the antigen-challenge phase protected the mice from TDI-induced airway eosinophilia. Moreover, rIL-17A exerted distinct effects on eosinophil- or neutrophil-related signatures in vitro. Conclusions: Our data demonstrated that IL-17A was required for the initiation of TDI-induced asthma, but functioned as a negative regulator of established allergic inflammation, suggesting that early abrogation of IL-17A signaling, but not late IL-17A neutralization, may prevent the progression of TDI-induced asthma and could be used as a therapeutic strategy for severe asthmatics in clinical settings.

      • KCI등재

        Zn-MOF loading Cu2O cube to construct hierarchical solid cage to improve photocatalytic hydrogen evolution

        Jing Xu,Zezhong Li,Zhenlu Liu,Shengming Xu,Xinyu Liu 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.126 No.-

        A novel composite is constructed by loading ZIF-8 on Cu2O by in situ growth. By visible light driven semiconductorand p-p* conjugation effect of the metal–organic framework, the migration ability of photogeneratedcarriers is improved, and electrons are accumulated to participate in hydrogen ionreduction. The superior hydrogen evolution performance (981.8 lmolg1h1) and stability test indicatethat the coupling of ZIF-8 and semiconductor Cu2O successfully improves the catalytic capacity of thematerial. Cu2O provides a place to stimulate activity for ZIF-8 with high specific surface area. The electrontransfer mechanism in composites is studied by electrochemical and spectroscopy methods. This workalso provides a new opportunity for the in-situ growth of metal–organic frame materials onto singlemetaloxides.

      • KCI등재

        Catalytic combustion of volatile aromatic compounds over CuO-CeO2 catalyst

        Hongmei Xie,Qinxiang Du,Hui Li,Guilin Zhou,Shengming Chen,Zhaojie Jiao,Jianmin Ren 한국화학공학회 2017 Korean Journal of Chemical Engineering Vol.34 No.7

        Ce1−xCuxO2 oxide solid solution catalysts with different Ce/Cu mole ratios were synthesized by the one-pot complex method. The prepared Ce1−xCuxO2 catalysts were characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and H2 temperature-programmed reduction (H2-TPR). Their catalytic properties were also investigated by catalytic combustion of phenyl volatile organic compounds (PVOCs: benzene, toluene, xylene, and ethylbenzene) in air. XRD analysis confirmed that the CuO species can fully dissolve into the CeO2 lattice to form CeCu oxide solid solutions. XPS and H2-TPR results indicated that the prepared Ce1−xCuxO2 catalysts contain abundant reactive oxygen species and superior reducibility. Furthermore, the physicochemical properties of the prepared Ce1−xCuxO2 catalysts are affected by the Ce/Cu mole ratio. The CeCu3 catalyst with Ce/Cu mole ratio of 3.0 contains abundant reactive oxygen species and exhibits superior catalytic combustion activity of PVOCs. Moreover, the ignitability of PVOCs is also affected by the respective physicochemical properties. The catalytic combustion conversions of ethylbenzene, xylene, toluene, and benzene are 99%, 98.9%, 94.3%, and 62.8% at 205, 220, 225, and 225 oC, respectively.

      • KCI등재

        Genetic localization of the SPC gene controlling pod coiling direction in Medicago truncatula

        Xiaocheng Yu,Qiulin Qin,Xia Wu,Dandan Li,Shengming Yang 한국유전학회 2020 Genes & Genomics Vol.42 No.7

        Background Handedness in plants introduced by helical growth of organs is frequently observed, and it has fascinated plant scientists for decades. However, the genetic control of natural handedness has not been revealed. In the model legume Medicago truncatula, pods can be coiled in a clockwise or anti-clockwise manner, providing a model for genetic analysis of plant handedness. Objective We aimed to localize the Sense of Pod Coiling (SPC) gene controlling pod coiling direction in M. truncatula. Methods Linkage analysis was used with a biparental population for fine mapping of the SPC gene. The genome sequence of M. truncatula Mt4.0 was used for marker identification and physical mapping. Single nucleotide polymorphisms (SNPs) between the parental lines were converted to CAPS (cleaved amplified polymorphic sequences) markers. Genetic map was constructed using the software JoinMap version 3.0. Gene predication and annotation provided by the M. truncatula genome database (http://www.medic agoge nome.org) was confirmed with the programs of FGENESH and Pfam 32.0, respectively. Quantitative reverse transcription PCR (qRT-PCR) was used to analyze the relative expression levels of candidate genes. Results The genetic analysis indicated that the anti-clockwise coiling is dominant to clockwise and is controlled by the single gene, SPC. The SPC gene was delimited to a 250 kb-region on Chromosome 7. Total of 15 protein-coding genes were identified in the SPC locus through gene annotation and sequence analysis. Of those, two genes, potentially encoding a receptor-like kinase and a vacuolar cation/proton exchanger respectively, were selected as candidates for the SPC gene. Conclusions The result presented here lay a foundation for gene cloning of SPC, which will help us to understand the molecular mechanisms underlying helical growth in plant organs.

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